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Neuroscience

D-Index
54
Citations
11047
World Ranking
4906
National Ranking
2205

Overview

Yukitoshi Izumi is affiliated with Washington University in St. Louis in the United States and has contributed extensively to research in neuroscience, medicine, and biochemistry, genetics, and molecular biology. Their work encompasses a variety of subfields including molecular biology, cellular and molecular neuroscience, ophthalmology, neurology, and surgery.

Their recent publications include:

  • A Proinflammatory Stimulus Disrupts Hippocampal Plasticity and Learning via Microglial Activation and 25-Hydroxycholesterol (2021, Journal of Neuroscience)
  • Nitrous Oxide, a Rapid Antidepressant, Has Ketamine-like Effects on Excitatory Transmission in the Adult Hippocampus (2022, Biological Psychiatry)

Yukitoshi Izumi's frequent co-authors are:

  • Charles F. Zorumski
  • Steven Mennerick
  • Makoto Ishikawa
  • Kazuko A. O'Dell
  • Hiroshi Kunikata

The main publication venues for their research include:

  • Neuroscience & Biobehavioral Reviews
  • Scientific Reports
  • Neural Regeneration Research
  • Biological Psychiatry
  • Translational Psychiatry

Their research covers multiple key topics, such as:

  • Neuroscience and Neuropharmacology Research
  • Cholesterol and Lipid Metabolism
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Tryptophan and brain disorders
  • Glaucoma and retinal disorders
  • Receptor Mechanisms and Signaling
  • Inflammasome and immune disorders

The profile of Yukitoshi Izumi's research indicates a focus on the mechanisms underlying neural function and dysfunction. This includes investigations into neuroinflammation, neuropharmacological effects, and cellular stress responses, as well as studies on retinal neuron protection.

Their work contributes to understanding complex processes such as hippocampal plasticity, excitatory transmission modulation, and the roles of neurosteroids and lipids in neuronal health and disease.

Best Publications

  • Early Exposure to Common Anesthetic Agents Causes Widespread Neurodegeneration in the Developing Rat Brain and Persistent Learning Deficits

    Vesna Jevtovic-Todorovic;Richard E. Hartman;Yukitoshi Izumi;Nicholas D. Benshoff

  • Acquired deficit of forebrain glucocorticoid receptor produces depression-like changes in adrenal axis regulation and behavior

    Maureen P. Boyle;Judson A. Brewer;Michiyo Funatsu;David F. Wozniak

  • Noradrenergic Regulation of Synaptic Plasticity in the Hippocampal CA1 Region

    Hiroshi Katsuki;Yukitoshi Izumi;Charles F. Zorumski

  • Inhibition of long-term potentiation by NMDA-mediated nitric oxide release.

    Yukitoshi Izumi;David B. Clifford;Charles F. Zorumski

  • The Major Brain Cholesterol Metabolite 24(S)-Hydroxycholesterol Is a Potent Allosteric Modulator of N-Methyl-d-Aspartate Receptors

    Steven M. Paul;James J. Doherty;Albert J. Robichaud;Gabriel M. Belfort

  • Ketamine: NMDA receptors and beyond

    Charles F. Zorumski;Yukitoshi Izumi;Steven Mennerick

  • Endogenous Monocarboxylates Sustain Hippocampal Synaptic Function and Morphological Integrity during Energy Deprivation

    Yukitoshi Izumi;Ann M. Benz;Hiroshi Katsuki;Charles F. Zorumski

  • Nitric oxide inhibitors attenuate excitotoxicity in rat hippocampal slices

    Yukitoshi Izumi;Ann M. Benz;David B. Clifford;Charles F. Zorumski

  • Neurosteroids, stress and depression: Potential therapeutic opportunities

    Charles F. Zorumski;Steven M. Paul;Yukitoshi Izumi;Douglas F. Covey

  • Acute and chronic effects of ethanol on learning-related synaptic plasticity.

    Charles F. Zorumski;Steven Mennerick;Yukitoshi Izumi

  • Treatment with an Amyloid-β Antibody Ameliorates Plaque Load, Learning Deficits, and Hippocampal Long-Term Potentiation in a Mouse Model of Alzheimer's Disease

    Richard E. Hartman;Yukitoshi Izumi;Kelly R. Bales;Steven M. Paul

  • Zinc Modulates Bidirectional Hippocampal Plasticity by Effects on NMDA Receptors

    Yukitoshi Izumi;Yves P. Auberson;Charles F. Zorumski

  • Effects of lactate and pyruvate on glucose deprivation in rat hippocampal slices.

    Yukitoshi Izumi;Ann M. Benz;Charles F. Zorumski;John W. Olney

  • NMDA receptors and metaplasticity: mechanisms and possible roles in neuropsychiatric disorders.

    Charles F. Zorumski;Yukitoshi Izumi

  • Norepinephrine promotes long-term potentiation in the adult rat hippocampus in vitro.

    Yukitoshi Izumi;Charles F. Zorumski

  • Nitric oxide and hippocampal synaptic plasticity

    Charles F. Zorumski;Yukitoshi Izumi

  • Acute effects of ethanol on hippocampal long-term potentiation and long-term depression are mediated by different mechanisms

    Y. Izumi;K. Nagashima;K. Murayama;C.F. Zorumski

  • Midazolam inhibits hippocampal long-term potentiation and learning through dual central and peripheral benzodiazepine receptor activation and neurosteroidogenesis.

    Kazuhiro Tokuda;Kazuko A. O'Dell;Yukitoshi Izumi;Charles F. Zorumski

  • Intracellular mGluR5 can mediate synaptic plasticity in the hippocampus.

    Carolyn A. Purgert;Yukitoshi Izumi;Yuh-Jiin I. Jong;Vikas Kumar

  • Nitric oxide and long-term synaptic depression in the rat hippocampus.

    Izumi Y;Zorumski Cf

  • Long-term potentiation requires activation of calcium-independent phospholipase A2

    Matthew J. Wolf;Yukitoshi Izumi;Charles F. Zorumski;Richard W. Gross

Frequent Co-Authors

Steven Mennerick
Steven Mennerick Washington University in St. Louis
Kelvin A. Yamada
Kelvin A. Yamada Washington University in St. Louis
Judson A. Brewer
Judson A. Brewer Brown University
David M. Holtzman
David M. Holtzman Washington University in St. Louis
Karen L. O'Malley
Karen L. O'Malley Washington University in St. Louis
Joe Z. Tsien
Joe Z. Tsien Augusta University
Slobodan M. Todorovic
Slobodan M. Todorovic University of Colorado Anschutz Medical Campus

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