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Neuroscience

D-Index
41
Citations
5198
World Ranking
7948
National Ranking
3411

Overview

Balapal S. Basavarajappa is affiliated with the Nathan Kline Institute for Psychiatric Research in the United States. Their research activity covers multiple fields primarily focused on medicine and biochemistry, genetics, and molecular biology.

The scientist's work spans various subfields including molecular biology, pharmacology, pediatrics, perinatology and child health, cellular and molecular neuroscience, and physiology.

Key thematic areas of their research encompass:

  • Cannabis and cannabinoid research
  • Epigenetics and DNA methylation
  • Prenatal substance exposure effects
  • Alzheimer's disease research and treatments
  • Retinal development and disorders
  • Neuroscience and neuropharmacology research
  • Cellular transport and secretion

Among the recent publications of Balapal S. Basavarajappa are:

  • Endosomal Dysfunction Induced by Directly Overactivating Rab5 Recapitulates Prodromal and Neurodegenerative Features of Alzheimer's Disease, 2020, Cell Reports
  • Histone Methylation Regulation in Neurodegenerative Disorders, 2021, International Journal of Molecular Sciences
  • Preclinical and randomized clinical evaluation of the p38α kinase inhibitor neflamapimod for basal forebrain cholinergic degeneration, 2022, Nature Communications
  • Postnatal Ethanol Exposure Activates HDAC-Mediated Histone Deacetylation, Impairs Synaptic Plasticity Gene Expression and Behavior in Mice, 2020, The International Journal of Neuropsychopharmacology
  • Molecular Insights into Epigenetics and Cannabinoid Receptors, 2022, Biomolecules

The scientist frequently publishes in venues such as Biomolecules, Brain Sciences, Preprints.org, Cell Reports, and the International Journal of Molecular Sciences.

Collaborations include multiple coauthors, with the most frequent being Shivakumar Subbanna, followed by Cynthia Bleiwas, Philip Stavrides, Ying Jiang, and Monika Pawlik.

Best Publications

  • Cannabinoid CB1 receptor knockout mice exhibit markedly reduced voluntary alcohol consumption and lack alcohol-induced dopamine release in the nucleus accumbens

    Basalingappa L Hungund;Basalingappa L Hungund;Basalingappa L Hungund;Istvan Szakall;Agota Adam;Balapal S Basavarajappa;Balapal S Basavarajappa

  • Upregulation of CB1 receptors and agonist-stimulated [35S]GTPgammaS binding in the prefrontal cortex of depressed suicide victims.

    B L Hungund;B L Hungund;B L Hungund;K Y Vinod;S A Kassir;B S Basavarajappa;B S Basavarajappa

  • Endocannabinoid system in neurodegenerative disorders.

    Balapal S. Basavarajappa;Madhu Shivakumar;Vikram Joshi;Shivakumar Subbanna

  • Chronic ethanol increases the cannabinoid receptor agonist anandamide and its precursor N-arachidonoylphosphatidylethanolamine in SK-N-SH cells.

    Balapal S Basavarajappa;Basalingappa L Hungund

  • Chronic ethanol administration down-regulates cannabinoid receptors in mouse brain synaptic plasma membrane.

    Balapal S. Basavarajappa;Thomas B. Cooper;Thomas B. Cooper;Basalingappa L. Hungund;Basalingappa L. Hungund

  • Stimulation of cannabinoid receptor agonist 2-arachidonylglycerol by chronic ethanol and its modulation by specific neuromodulators in cerebellar granule neurons

    Balapal S. Basavarajappa;Mariko Saito;Thomas B. Cooper;Basalingappa L. Hungund

  • Chronic ethanol inhibits the anandamide transport and increases extracellular anandamide levels in cerebellar granule neurons.

    Balapal S. Basavarajappa;Mariko Saito;Thomas B. Cooper;Thomas B. Cooper;Basalingappa L. Hungund;Basalingappa L. Hungund

  • Calpain Mediates Calcium-Induced Activation of the Erk1,2 MAPK Pathway and Cytoskeletal Phosphorylation in Neurons: Relevance to Alzheimer's Disease

    Veeranna;Takahide Kaji;Barry Boland;Barry Boland;Tatjana Odrljin

  • Neuropharmacology of the Endocannabinoid Signaling System-Molecular Mechanisms, Biological Actions and Synaptic Plasticity

    Balapal S. Basavarajappa

  • Neurofilament Subunits are Integral Components of Synapses and Modulate Neurotransmission and Behavior In Vivo

    A Yuan;H Sershen;Veeranna;B S Basavarajappa

  • Increased ethanol consumption and preference and decreased ethanol sensitivity in female FAAH knockout mice.

    Balapal S. Basavarajappa;Ratnakumar Yalamanchili;Benjamin F. Cravatt;Thomas B. Cooper;Thomas B. Cooper;Thomas B. Cooper

  • Neuromodulatory role of the endocannabinoid signaling system in alcoholism: an overview.

    B.S. Basavarajappa;B.S. Basavarajappa;B.L. Hungund

  • Acute ethanol suppresses glutamatergic neurotransmission through endocannabinoids in hippocampal neurons.

    Balapal S. Basavarajappa;Ipe Ninan;Ottavio Arancio

  • Elevation of endogenous anandamide impairs LTP, learning, and memory through CB1 receptor signaling in mice

    Balapal S. Basavarajappa;Balapal S. Basavarajappa;Nagaraja N. Nagre;Shan Xie;Shivakumar Subbanna

  • Endocannabinoid system: emerging role from neurodevelopment to neurodegeneration.

    Balapal S. Basavarajappa;Ralph A. Nixon;Ottavio Arancio

  • Anandamide-CB1 Receptor Signaling Contributes to Postnatal Ethanol-Induced Neonatal Neurodegeneration, Adult Synaptic and Memory Deficits

    Shivakumar Subbanna;Madhu Shivakumar;Delphine Psychoyos;Shan Xie

  • Down-regulation of cannabinoid receptor agonist-stimulated [35S]GTPγS binding in synaptic plasma membrane from chronic ethanol exposed mouse

    Balapal S. Basavarajappa;Basalingappa L. Hungund

  • G9a-mediated histone methylation regulates ethanol-induced neurodegeneration in the neonatal mouse brain.

    Shivakumar Subbanna;Madhu Shivakumar;Nagavedi S. Umapathy;Mariko Saito;Mariko Saito

  • Endosomal Dysfunction Induced by Directly Overactivating Rab5 Recapitulates Prodromal and Neurodegenerative Features of Alzheimer's Disease.

    Anna Pensalfini;Anna Pensalfini;Seonil Kim;Seonil Kim;Shivakumar Subbanna;Cynthia Bleiwas

  • Ethanol, endocannabinoids, and the cannabinoidergic signaling system.

    Basalingappa L. Hungund;Balapal S. Basavarajappa;Csaba Vadasz;George Kunos

  • CB1-receptor knockout neonatal mice are protected against ethanol-induced impairments of DNMT1, DNMT3A, and DNA methylation.

    Nagaraja N. Nagre;Shivakumar Subbanna;Madhu Shivakumar;Delphine Psychoyos

Frequent Co-Authors

Ralph A. Nixon
Ralph A. Nixon Nathan Kline Institute for Psychiatric Research
Ottavio Arancio
Ottavio Arancio Columbia University
Donald A. Wilson
Donald A. Wilson Nathan Kline Institute for Psychiatric Research
John F. Smiley
John F. Smiley Nathan Kline Institute for Psychiatric Research
Henry Sershen
Henry Sershen New York University
Niels D. Prins
Niels D. Prins Vrije Universiteit Amsterdam
Fernando Rodríguez de Fonseca
Fernando Rodríguez de Fonseca Complutense University of Madrid
Stephen D. Ginsberg
Stephen D. Ginsberg Nathan Kline Institute for Psychiatric Research
Loren H. Parsons
Loren H. Parsons Scripps Research Institute
Paul Maruff
Paul Maruff University of Melbourne

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