Asok Kumar

Overview

Best Publications

• Extensive involvement of autophagy in Alzheimer disease: an immuno-electron microscopy study.

  Ralph A. Nixon;Ralph A. Nixon;Jerzy Wegiel;Asok Kumar;Asok Kumar;Wai Haung Yu;Wai Haung Yu

  1834
  Citations

• Lysosomal Proteolysis and Autophagy Require Presenilin 1 and Are Disrupted by Alzheimer-Related PS1 Mutations

  Ju Hyun Lee;Ju Hyun Lee;W. Haung Yu;W. Haung Yu;Asok Kumar;Asok Kumar;Sooyeon Lee;Sooyeon Lee

  1342
  Citations

• Autophagy Induction and Autophagosome Clearance in Neurons: Relationship to Autophagic Pathology in Alzheimer's Disease

  B Boland;A Kumar;S Lee;F M Platt

  1273
  Citations

• Macroautophagy—a novel β-amyloid peptide-generating pathway activated in Alzheimer's disease

  W Haung Yu;Ana Maria Cuervo;Asok Kumar;Corrinne M. Peterhoff

  1195
  Citations

• Reversal of autophagy dysfunction in the TgCRND8 mouse model of Alzheimer's disease ameliorates amyloid pathologies and memory deficits.

  Dun Sheng Yang;Dun Sheng Yang;Philip Stavrides;Panaiyur S. Mohan;Panaiyur S. Mohan;Susmita Kaushik

  504
  Citations

• Autophagy failure in Alzheimer's disease and the role of defective lysosomal acidification.

  Devin M. Wolfe;Ju-hyun Lee;Ju-hyun Lee;Asok Kumar;Asok Kumar;Sooyeon Lee

  438
  Citations

• Autophagic vacuoles are enriched in amyloid precursor protein-secretase activities: implications for β-amyloid peptide over-production and localization in Alzheimer’s disease ☆

  W. H. Yu;A. Kumar;C. Peterhoff;L. Shapiro Kulnane

  380
  Citations

• The Exosome Secretory Pathway Transports Amyloid Precursor Protein Carboxyl-terminal Fragments from the Cell into the Brain Extracellular Space

  Rocio Perez-Gonzalez;Sebastien A. Gauthier;Asok Kumar;Efrat Levy

  380
  Citations

• Lipidation of apolipoprotein E influences its isoform-specific interaction with Alzheimer's amyloid β peptides

  Takahiko Tokuda;Miguel Calero;Etsuro Matsubara;Ruben Vidal

  347
  Citations

• Presenilin 1 Maintains Lysosomal Ca2+ Homeostasis via TRPML1 by Regulating vATPase-Mediated Lysosome Acidification

  Ju-Hyun Lee;Mary Kate McBrayer;Devin M. Wolfe;Luke J. Haslett

  322
  Citations

• Codeposition of Cystatin C with Amyloid-β Protein in the Brain of Alzheimer Disease Patients

  Efrat Levy;Magdalena Sastre;Asok Kumar;Gloria Gallo

  249
  Citations

• Alpha-internexin is structurally and functionally associated with the neurofilament triplet proteins in the mature CNS.

  Aidong Yuan;Mala V Rao;Takahiro Sasaki;Yuanxin Chen

  246
  Citations

• Neuronal Apoptosis and Autophagy Cross Talk in Aging PS/APP Mice, a Model of Alzheimer's Disease

  Dun-Sheng Yang;Dun-Sheng Yang;Asok Kumar;Asok Kumar;Philip Stavrides;Jesse Peterson

  208
  Citations

• Axonal transport rates in vivo are unaffected by tau deletion or overexpression in mice.

  Aidong Yuan;Asok Kumar;Corrinne Peterhoff;Karen Duff

  206
  Citations

• Binding of cystatin C to Alzheimer’s amyloid β inhibits in vitro amyloid fibril formation

  Magdalena Sastre;Miguel Calero;Monika Pawlik;Monika Pawlik;Paul M Mathews;Paul M Mathews

  205
  Citations

• Biochemical characterization of Alzheimer's soluble amyloid beta protein in human cerebrospinal fluid: association with high density lipoproteins.

  Alexei R. Koudinov;Natalia V. Koudinova;Asok Kumar;Ronald C. Beavis

  198
  Citations

• β-sheet breaker peptide inhibitor of Alzheimer's amyloidogenesis with increased blood–brain barrier permeability and resistance to proteolytic degradation in plasma

  Joseph F. Poduslo;Geoffry L. Curran;Asok Kumar;Blas Frangione

  172
  Citations

• The neurofilament middle molecular mass subunit carboxyl-terminal tail domains is essential for the radial growth and cytoskeletal architecture of axons but not for regulating neurofilament transport rate

  Mala V. Rao;Jabbar Campbell;Aidong Yuan;Asok Kumar

  167
  Citations

• Induction of autophagy by cystatin C: a mechanism that protects murine primary cortical neurons and neuronal cell lines.

  Belen Tizon;Susmita Sahoo;Haung Yu;Sebastien Gauthier

  166
  Citations

• Alzheimer's amyloid β interaction with normal human plasma high density lipoprotein : Association with apolipoprotein and lipids

  Alexei R Koudinov;Temirbolat T Berezov;Asok Kumar;Natalia V Koudinova;Natalia V Koudinova

  159
  Citations