Markus G. Grütter

Overview

Best Publications

• High-affinity binders selected from designed ankyrin repeat protein libraries.

  H Kaspar Binz;Patrick Amstutz;Andreas Kohl;Michael T Stumpp

  856
  Citations

• TRIM5 is an innate immune sensor for the retrovirus capsid lattice

  Thomas Pertel;Stéphane Hausmann;Damien Morger;Sara Züger

  772
  Citations

• Structure-based design of aliskiren, a novel orally effective renin inhibitor.

  Jeanette M Wood;Jürgen Maibaum;Joseph Rahuel;Markus G Grütter

  728
  Citations

• Caspases: key players in programmed cell death.

  Markus G Grütter

  677
  Citations

• The Long Form of FLIP Is an Activator of Caspase-8 at the Fas Death-inducing Signaling Complex

  Olivier Micheau;Margot Thome;Pascal Schneider;Nils Holler

  647
  Citations

• Drug Export Pathway of Multidrug Exporter AcrB Revealed by DARPin Inhibitors

  Gaby Sennhauser;Patrick Amstutz;Christophe Briand;Otso Storchenegger

  428
  Citations

• Insights into the regulatory mechanism for caspase-8 activation.

  Mrudula Donepudi;Aengus Mac Sweeney;Christophe Briand;Markus G Grütter

  418
  Citations

• The SPRY domain of Pyrin, mutated in familial Mediterranean fever patients, interacts with inflammasome components and inhibits proIL-1beta processing.

  Papin S;Cuenin S;Agostini L;Martinon F

  416
  Citations

• Precision is essential for efficient catalysis in an evolved Kemp eliminase

  Rebecca Blomberg;Hajo Kries;Daniel M. Pinkas;Peer R. E. Mittl

  368
  Citations

• Designed to be stable: Crystal structure of a consensus ankyrin repeat protein

  Andreas Kohl;H. Kaspar Binz;Patrik Forrer;Michael T. Stumpp

  366
  Citations

• Transport of drugs by the multidrug transporter AcrB involves an access and a deep binding pocket that are separated by a switch-loop

  Thomas Eicher;Hi-jea Cha;Markus A. Seeger;Lorenz Brandstätter

  365
  Citations

• Structure of recombinant human CPP32 in complex with the tetrapeptide acetyl-Asp-Val-Ala-Asp fluoromethyl ketone.

  Peer R.E. Mittl;Stefania Di Marco;Joseph F. Krebs;Xu Bai

  365
  Citations

• Crystal structure of a heterodimeric ABC transporter in its inward-facing conformation

  Michael Hohl;Christophe Briand;Markus G Grütter;Markus A Seeger

  332
  Citations

• The 2.5 A X-ray crystal structure of the acid-stable proteinase inhibitor from human mucous secretions analysed in its complex with bovine alpha-chymotrypsin.

  M. G. Grütter;G. Fendrich;R. Huber;W. Bode

  302
  Citations

• Crystal Structure of the Multidrug Exporter MexB from Pseudomonas aeruginosa

  Gaby Sennhauser;Magdalena A. Bukowska;Christophe Briand;Markus G. Grütter

  299
  Citations

• Crystal structure and functional analysis of escherichia coli glutamate decarboxylase

  Guido Capitani;Daniela De Biase;Caterina Aurizi;Heinz Gut

  298
  Citations

• Structural basis for specificity of Grb2-SH2 revealed by a novel ligand binding mode.

  Joseph Rahuel;Dirk Erdmann;André Strauss

  286
  Citations

• The three-dimensional structure of caspase-8: an initiator enzyme in apoptosis

  Helen Blanchard;Lalitha Kodandapani;Peer Re Mittl;Stefania Di Marco

  240
  Citations

• NLRP3 tyrosine phosphorylation is controlled by protein tyrosine phosphatase PTPN22

  Marianne R. Spalinger;Stephanie Kasper;Claudia Gottier;Silvia Lang

  239
  Citations

• Structural basis and kinetics of inter- and intramolecular disulfide exchange in the redox catalyst DsbD

  Anna Rozhkova;Christian U Stirnimann;Patrick Frei;Ulla Grauschopf

  188
  Citations