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Biology and Biochemistry

D-Index
67
Citations
20929
World Ranking
8087
National Ranking
3662

Overview

Sina A. Gharib is affiliated with the University of Washington in the United States. Their research spans multiple fields with a strong focus on medicine, particularly in pulmonary and respiratory medicine, and intersects significantly with biochemistry, genetics, and molecular biology.

Their subfields of study include pulmonary and respiratory medicine, molecular biology, physiology, genetics, and epidemiology. These areas frame the breadth of Gharib's scientific inquiries and scholarly contributions.

Gharib's main research topics cover a spectrum of concerns in respiratory and genetic health, including:

  • Chronic Obstructive Pulmonary Disease (COPD) Research
  • Genetic Associations and Epidemiology
  • Obstructive Sleep Apnea Research
  • Epigenetics and DNA Methylation
  • Pulmonary Hypertension Research and Treatments
  • Asthma and respiratory diseases
  • Respiratory viral infections research

Their recent notable publications include:

  • "Genetic diversity fuels gene discovery for tobacco and alcohol use", 2022, Nature
  • "Association Between Preserved Ratio Impaired Spirometry and Clinical Outcomes in US Adults", 2021, JAMA
  • "Association of clonal hematopoiesis with chronic obstructive pulmonary disease", 2021, Blood
  • "Identification of 371 genetic variants for age at first sex and birth linked to externalising behaviour", 2021, Nature Human Behaviour
  • "Cell-Type-Specific Immune Dysregulation in Severely Ill COVID-19 Patients", 2020, Cell Reports

The frequent co-authors collaborating with Gharib are:

  • Stephen S. Rich
  • Tamar Sofer
  • Traci M. Bartz
  • Jerome I. Rotter
  • Susan Redline

Their work is published across a variety of academic venues, with the most frequent including:

  • UNC Libraries
  • bioRxiv (Cold Spring Harbor Laboratory)
  • American Journal of Respiratory and Critical Care Medicine
  • American Journal of Physiology-Lung Cellular and Molecular Physiology
  • Scientific Reports

Best Publications

  • Large-scale cis- and trans-eQTL analyses identify thousands of genetic loci and polygenic scores that regulate blood gene expression

    Urmo Võsa;Annique Claringbould;Annique Claringbould;Harm-Jan Westra;Marc Jan Bonder

  • Systematic identification of trans eQTLs as putative drivers of known disease associations

    Harm-Jan Westra;Marjolein J Peters;Tõnu Esko;Hanieh Yaghootkar

  • Shotgun proteomics implicates protease inhibition and complement activation in the antiinflammatory properties of HDL

    Tomas Vaisar;Subramaniam Pennathur;Pattie S. Green;Sina A. Gharib

  • Epigenetic Signatures of Cigarette Smoking

    Roby Joehanes;Allan C. Just;Riccardo E. Marioni;Luke C. Pilling

  • Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences

    Richard Karlsson Linnér;Richard Karlsson Linnér;Pietro Biroli;Edward Kong;S. Fleur W. Meddens;S. Fleur W. Meddens

  • The transcriptional landscape of age in human peripheral blood

    Marjolein J. Peters;Roby Joehanes;Luke C. Pilling;Claudia Schurmann;Claudia Schurmann

  • Meta-analyses of genome-wide association studies identify multiple loci associated with pulmonary function

    Dana B. Hancock;Mark Eijgelsheim;Jemma B. Wilk;Sina A. Gharib

  • Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks

    Florence Demenais;Florence Demenais;Patricia Margaritte-Jeannin;Patricia Margaritte-Jeannin;Kathleen C. Barnes;William O.C. Cookson

  • Unraveling the polygenic architecture of complex traits using blood eQTL metaanalysis

    Võsa U;Claringbould A;Westra H;Bonder Mj

  • Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function

    María Soler Artigas;Daan W. Loth;Louise V. Wain;Sina A. Gharib

  • Genetic loci associated with chronic obstructive pulmonary disease overlap with loci for lung function and pulmonary fibrosis

    Brian D. Hobbs;Kim De Jong;Maxime Lamontagne;Yohan Bossé

  • Common variants in 22 loci are associated with QRS duration and cardiac ventricular conduction.

    Nona Sotoodehnia;Aaron Isaacs;Paul I W de Bakker;Marcus Dörr

  • Genetic landscape of chronic obstructive pulmonary disease identifies heterogeneous cell-type and phenotype associations

    Phuwanat Sakornsakolpat;Phuwanat Sakornsakolpat;Dmitry Prokopenko;Dmitry Prokopenko;Maxime Lamontagne;Nicola F Reeve

  • Role of lung pericytes and resident fibroblasts in the pathogenesis of pulmonary fibrosis.

    Chi Hung;Geoffrey Linn;Yu Hua Chow;Akio Kobayashi

  • Genome-wide association studies identify CHRNA5/3 and HTR4 in the development of airflow obstruction.

    Jemma B. Wilk;Jemma B. Wilk;Nick R.G. Shrine;Laura R. Loehr;Jing Hua Zhao

  • Cellular Mechanisms of Tissue Fibrosis. 3. Novel mechanisms of kidney fibrosis

    Gabriela Campanholle;Giovanni Ligresti;Sina A. Gharib;Jeremy S. Duffield

  • Pericyte TIMP3 and ADAMTS1 Modulate Vascular Stability after Kidney Injury

    Claudia Schrimpf;Cuiyan Xin;Gabriella Campanholle;Sean E. Gill

  • Prediction of mechanical properties of human atherosclerotic tissue by high-frequency intravascular ultrasound imaging. An in vitro study.

    R T Lee;S G Richardson;H M Loree;A J Grodzinsky

  • Genetic landscape of chronic obstructive pulmonary disease identifies heterogeneous cell-type and phenotype associations

    Phuwanat Sakornsakolpat;Dmitry Prokopenko;Maxime Lamontagne;Nicola F. Reeve

  • Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks

    Florence Demenais;Patricia Margaritte-Jeannin;Kathleen C. Barnes;William O. C. Cookson

Frequent Co-Authors

Bruce M. Psaty
Bruce M. Psaty University of Washington
Susan Redline
Susan Redline Brigham and Women's Hospital
George T. O'Connor
George T. O'Connor Boston University
Daniel J. Gottlieb
Daniel J. Gottlieb Brigham and Women's Hospital
Guy Brusselle
Guy Brusselle Ghent University Hospital
Jerome I. Rotter
Jerome I. Rotter UCLA Medical Center
Stephanie J. London
Stephanie J. London National Institutes of Health
Martin D. Tobin
Martin D. Tobin University of Leicester
Josée Dupuis
Josée Dupuis McGill University
André G. Uitterlinden
André G. Uitterlinden Erasmus University Rotterdam

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Related Online Degrees & Career Pathways

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With the growing demand for skilled professionals in these linked areas, earning an online degree can offer flexibility and strong job prospects for those with a background in Biology or Biochemistry.

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