World's Best Scientists 2026 revealed!
Josée Dupuis

Josée Dupuis

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Best Female Scientists
2025

D-Index & Metrics

Best Female Scientists

D-Index
111
Citations
61210
World Ranking
833
National Ranking
26

Genetics

D-Index
110
Citations
58776
World Ranking
530
National Ranking
17

Biology and Biochemistry

D-Index
111
Citations
59691
World Ranking
924
National Ranking
21

Medicine

D-Index
112
Citations
60520
World Ranking
5069
National Ranking
197

Research.com Recognitions

  • 2025 - Research.com Best Female Scientists Award
  • 2014 - Fellow of the American Association for the Advancement of Science (AAAS)
  • 2013 - Fellow of the American Statistical Association (ASA)

Overview

Josée Dupuis is a researcher affiliated with McGill University in Canada specializing in biochemistry, genetics, and molecular biology, with a significant focus on medicine. Their work spans various subfields, including genetics, molecular biology, pulmonary and respiratory medicine, physiology, and epidemiology.

The scientist's research centers on key topics such as genetic associations and epidemiology, chronic obstructive pulmonary disease (COPD) research, genomics and rare diseases, epigenetics and DNA methylation, bioinformatics and genomic networks, asthma and respiratory diseases, and genomic variations and chromosomal abnormalities.

Among recent papers authored or co-authored by Josée Dupuis are:

  • The mutational constraint spectrum quantified from variation in 141,456 humans, 2020, Nature
  • A genomic mutational constraint map using variation in 76,156 human genomes, 2023, Nature
  • Host and gut microbial tryptophan metabolism and type 2 diabetes: an integrative analysis of host genetics, diet, gut microbiome and circulating metabolites in cohort studies, 2021, Gut
  • Transcript expression-aware annotation improves rare variant interpretation, 2020, Nature
  • Cerebral small vessel disease genomics and its implications across the lifespan, 2020, Nature Communications

Frequent co-authors collaborating with Dupuis include:

  • James B. Meigs
  • Jerome I. Rotter
  • George O'connor
  • José C. Florez
  • Bruce M. Psaty

Their publications have appeared in numerous venues, with the most frequent including:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • UNC Libraries
  • Nature Communications
  • Alzheimer's & Dementia
  • American Journal of Respiratory and Critical Care Medicine

Josée Dupuis has been recognized with awards including being named Fellow of the American Association for the Advancement of Science (AAAS) in 2014 and Fellow of the American Statistical Association (ASA) in 2013.

Best Publications

  • New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

    Josée Dupuis;Josée Dupuis;Claudia Langenberg;Inga Prokopenko;Richa Saxena;Richa Saxena

  • New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk (vol 42, pg 105, 2010)

    J Dupuis;C Langenberg;I Prokopenko;R Saxena

  • Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis

    Benjamin F. Voight;Benjamin F. Voight;Laura J. Scott;Valgerdur Steinthorsdottir;Andrew P. Morris

  • Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes

    Andrew P Morris;Benjamin F Voight;Benjamin F Voight;Tanya M Teslovich;Teresa Ferreira

  • Common genetic determinants of vitamin D insufficiency: a genome-wide association study

    Thomas J. Wang;Feng Zhang;J. Brent Richards;Bryan Kestenbaum

  • A genome-wide association search for type 2 diabetes genes in African Americans.

    N D Palmer;C W McDonough;P J Hicks;B H Roh

  • Fine-mapping type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps.

    Anubha Mahajan;Daniel Taliun;Matthias Thurner;Neil R. Robertson

  • Common variants at 30 loci contribute to polygenic dyslipidemia.

    Sekar Kathiresan;Sekar Kathiresan;Sekar Kathiresan;Cristen J. Willer;Gina M. Peloso;Serkalem Demissie

  • Association of the ADAM33 gene with asthma and bronchial hyperresponsiveness

    Paul Van Eerdewegh;Randall D. Little;Josée Dupuis;Richard G. Del Mastro

  • A mutation in the LDL receptor-related protein 5 gene results in the autosomal dominant high-bone-mass trait.

    Randall D. Little;John P. Carulli;Richard G. Del Mastro;Josée Dupuis

  • The genetic architecture of type 2 diabetes

    Christian Fuchsberger;Christian Fuchsberger;Jason A. Flannick;Jason A. Flannick;Tanya M. Teslovich;Anubha Mahajan

  • Causal relationship between obesity and vitamin D status: bi-directional Mendelian randomization analysis of multiple cohorts.

    Karani S. Vimaleswaran;Diane J. Berry;Emmi Tikkanen;Emmi Tikkanen;Stefan Pilz;Stefan Pilz

  • Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease

    Rebecca Sims;Sven J. Van Der Lee;Adam C. Naj;Céline Bellenguez;Céline Bellenguez

  • Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility.

    Anubha Mahajan;Min Jin Go;Weihua Zhang;Jennifer E. Below

  • Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways

    Robert A Scott;Vasiliki Lagou;Ryan P Welch;Eleanor Wheeler

  • Variants in MTNR1B influence fasting glucose levels

    Inga Prokopenko;Claudia Langenberg;Jose C. Florez;Jose C. Florez;Richa Saxena;Richa Saxena

  • Genotype Score in Addition to Common Risk Factors for Prediction of Type 2 Diabetes

    James B. Meigs;Peter Shrader;Lisa M. Sullivan;Jarred B. McAteer

  • Erratum: New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk (Nature Genetics (2010) 42 (105-116))

    Josée Dupuis;Claudia Langenberg;Inga Prokopenko;Richa Saxena

  • The genetic architecture of type 2 diabetes

    Christian Fuchsberger;Jason Flannick;Tanya M. Teslovich;Anubha Mahajan

  • Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility

    Anubha Mahajan;Min Jin Go;Weihua Zhang;Jennifer E. Below

Frequent Co-Authors

James B. Meigs
James B. Meigs Harvard University
Jose C. Florez
Jose C. Florez Harvard University
Bruce M. Psaty
Bruce M. Psaty University of Washington
Erik Ingelsson
Erik Ingelsson Stanford University
Eric Boerwinkle
Eric Boerwinkle The University of Texas Health Science Center at Houston
Nicholas J. Wareham
Nicholas J. Wareham University of Cambridge
Andrew P. Morris
Andrew P. Morris University of Liverpool
George T. O'Connor
George T. O'Connor Boston University
Inga Prokopenko
Inga Prokopenko University of Surrey

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