World's Best Scientists 2026 revealed!

D-Index & Metrics

Genetics

D-Index
67
Citations
17164
World Ranking
2524
National Ranking
1129

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Internal medicine
  • Genetics

His main research concerns Genetics, Genetic variation, Allele, Haplotype and Gene. As part of his studies on Genetics, Charles F. Sing often connects relevant subjects like Blood pressure. His biological study spans a wide range of topics, including Nucleotide diversity, Population size, Confounding and Candidate gene.

Charles F. Sing works mostly in the field of Allele, limiting it down to topics relating to Apolipoprotein E and, in certain cases, Cholesterol and Genetic variability. His Haplotype research focuses on Genetic association and how it relates to Genetic heterogeneity, Phylogenetic tree and Clade. His Gene research is multidisciplinary, relying on both Disease risk and Burden of disease.

His most cited work include:

  • A Cladistic Analysis of Phenotypic Associations With Haplotypes Inferred From Restriction Endonuclease Mapping. I. Basic Theory and an Analysis of Alcohol Dehydrogenase Activity in Drosophila (704 citations)
  • DNA sequence diversity in a 9.7-kb region of the human lipoprotein lipase gene (467 citations)
  • Haplotype structure and population genetic inferences from nucleotide- sequence variation in human lipoprotein lipase (432 citations)

What are the main themes of his work throughout his whole career to date?

Charles F. Sing mainly focuses on Genetics, Internal medicine, Genetic variation, Endocrinology and Genotype. His research is interdisciplinary, bridging the disciplines of Apolipoprotein E and Genetics. His research investigates the connection between Apolipoprotein E and topics such as Apolipoprotein B that intersect with issues in Lipoprotein.

The study incorporates disciplines such as Genetic variability, Nucleotide diversity, Linkage disequilibrium, Haplotype and Candidate gene in addition to Genetic variation. His Endocrinology research is multidisciplinary, incorporating perspectives in Antigen, Increased risk and Lymphocyte. His study in the field of Polymorphism also crosses realms of Context.

He most often published in these fields:

  • Genetics (50.29%)
  • Internal medicine (28.90%)
  • Genetic variation (26.59%)

What were the highlights of his more recent work (between 2004-2015)?

  • Genetics (50.29%)
  • Single-nucleotide polymorphism (10.98%)
  • Genotype (21.97%)

In recent papers he was focusing on the following fields of study:

His scientific interests lie mostly in Genetics, Single-nucleotide polymorphism, Genotype, Disease and Apolipoprotein E. His work on Allele, Genetic association, Haplotype and Gene as part of general Genetics research is often related to Context, thus linking different fields of science. His Haplotype research includes elements of Genetic variation and Population genetics.

His study on Polymorphism is often connected to Variation as part of broader study in Genotype. His research integrates issues of Oncology, Genetic predisposition and Allele frequency in his study of Apolipoprotein E. As part of one scientific family, Charles F. Sing deals mainly with the area of Internal medicine, narrowing it down to issues related to the Endocrinology, and often Increased risk and Apoa5 gene.

Between 2004 and 2015, his most popular works were:

  • Deep resequencing reveals excess rare recent variants consistent with explosive population growth (217 citations)
  • Neutral genomic regions refine models of recent rapid human population growth (91 citations)
  • Tree Scanning: A Method for Using Haplotype Trees in Phenotype/Genotype Association Studies (86 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Internal medicine
  • Genetics

His primary areas of investigation include Genetics, Genetic association, Genetic variation, Single-nucleotide polymorphism and Haplotype. His studies in Genetics integrate themes in fields like Population growth, Natural selection and Disease risk. His Genetic variation research incorporates themes from Coronary artery disease, Increased risk, Young adult and Apoa5 gene.

Charles F. Sing focuses mostly in the field of Single-nucleotide polymorphism, narrowing it down to matters related to Cholesterol and, in some cases, Candidate gene and Apolipoprotein E. Charles F. Sing has included themes like Endocrinology, Internal medicine and Apolipoprotein B in his Candidate gene study. His study with Haplotype involves better knowledge in Allele.

Best Publications

  • A Cladistic Analysis of Phenotypic Associations With Haplotypes Inferred From Restriction Endonuclease Mapping. I. Basic Theory and an Analysis of Alcohol Dehydrogenase Activity in Drosophila

    Alan R. Templeton;Eric Boerwinkle;Charles F. Sing

  • DNA sequence diversity in a 9.7-kb region of the human lipoprotein lipase gene

    Deborah A. Nickerson;Scott L. Taylor;Kenneth M. Weiss;Andrew G. Clark

  • Haplotype structure and population genetic inferences from nucleotide- sequence variation in human lipoprotein lipase

    Andrew G. Clark;Kenneth M. Weiss;Deborah A. Nickerson;Scott L. Taylor

  • Apolipoprotein E Variation at the Sequence Haplotype Level: Implications for the Origin and Maintenance of a Major Human Polymorphism

    Stephanie M. Fullerton;Andrew G. Clark;Kenneth M. Weiss;Deborah A. Nickerson

  • A Combinatorial Partitioning Method to Identify Multilocus Genotypic Partitions That Predict Quantitative Trait Variation

    M.R. Nelson;S.L.R. Kardia;R.E. Ferrell;C.F. Sing

  • The use of measured genotype information in the analysis of quantitative phenotypes in man. I. Models and analytical methods.

    E. Boerwinkle;R. Chakraborty;C. F. Sing

  • The use of measured genotype information in the analysis of quantitative phenotypes in man

    Eric Boerwinkle;C. F. Sing

  • Genome-Wide Linkage Analyses of Systolic Blood Pressure Using Highly Discordant Siblings

    Julia Krushkal;Robert Ferrell;Stephen C. Mockrin;Stephen T. Turner

  • The use of measured genotype information in the analysis of quantitative phenotypes in man. II. The role of the apolipoprotein E polymorphism in determining levels, variability, and covariability of cholesterol, betalipoprotein, and triglycerides in a sample of unrelated individuals

    Eric Boerwinkle;S. Visvikis;D. Welsh;J. Steinmetz

  • Genes, Environment, and Cardiovascular Disease

    Charles F. Sing;Jari H. Stengård;Sharon L.R. Kardia

  • Multi-center genetic study of hypertension: The Family blood pressure program (FBPP)

    Eric Boerwinkle;C. Andrew Brown;Maurita Carrejo;Robert Ferrell

  • Deep resequencing reveals excess rare recent variants consistent with explosive population growth

    Alex Coventry;Lara M. Bull-Otterson;Xiaoming Liu;Andrew G. Clark

  • Variation in the Region of the Angiotensin-Converting Enzyme Gene Influences Interindividual Differences in Blood Pressure Levels in Young White Males

    Myriam Fornage;Christopher I. Amos;Sharon Kardia;Charles F. Sing

  • Recombinational and mutational hotspots within the human lipoprotein lipase gene.

    Alan R. Templeton;Andrew G. Clark;Kenneth M. Weiss;Deborah A. Nickerson

  • Positional Genomic Analysis Identifies the β2-Adrenergic Receptor Gene as a Susceptibility Locus for Human Hypertension

    Molly S. Bray;Julia Krushkal;Li Li;Robert Ferrell

  • Sequence Diversity and Large-Scale Typing of SNPs in the Human Apolipoprotein E Gene

    Deborah A. Nickerson;Scott L. Taylor;Stephanie M. Fullerton;Kenneth M. Weiss

  • Effects of polymorphisms in apolipoproteins E, A-IV, and H on quantitative traits related to risk for cardiovascular disease.

    J Kaprio;R E Ferrell;B A Kottke;M I Kamboh

  • FAMILIAL AGGREGATION OF BLOOD PRESSURE AND WEIGHT IN ADOPTIVE FAMILIES II. ESTIMATION OF THE RELATIVE CONTRIBUTIONS OF GENETIC AND COMMON ENVIRONMENTAL FACTORS TO BLOOD PRESSURE CORRELATIONS BETWEEN FAMILY MEMBERS

    Joseph L. Annest;Charles F. Sing;Pierre Biron;Jean Guy Mongeau

  • The gender-specific apolipoprotein E genotype influence on the distribution of lipids and apolipoproteins in the population of Rochester, MN. I. Pleiotropic effects on means and variances.

    Sharon L. Reilly;Robert E. Ferrell;Bruce A. Kottke;Mohammad I. Kamboh

  • Etiologic heterogeneity in alcoholism.

    Sheila B. Gilligan;Theodore Reich;C. Robert Cloninger;Charles F. Sing

Frequent Co-Authors

Eric Boerwinkle
Eric Boerwinkle The University of Texas Health Science Center at Houston
andrew g clark
andrew g clark Cornell University
Sharon L.R. Kardia
Sharon L.R. Kardia University of Michigan–Ann Arbor
Robert E. Ferrell
Robert E. Ferrell University of Pittsburgh
George J. Brewer
George J. Brewer University of Michigan–Ann Arbor
Alan R. Templeton
Alan R. Templeton Washington University in St. Louis
Anne Tybjærg-Hansen
Anne Tybjærg-Hansen University of Copenhagen
Kenneth M. Weiss
Kenneth M. Weiss Pennsylvania State University
Veikko Salomaa
Veikko Salomaa Finnish Institute for Health and Welfare

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