H-Index & Metrics Best Publications

H-Index & Metrics

Discipline name H-index Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 72 Citations 26,070 137 World Ranking 2623 National Ranking 1384
Medicine D-index 74 Citations 23,930 128 World Ranking 12450 National Ranking 6599

Research.com Recognitions

Awards & Achievements

1987 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

What is he best known for?

The fields of study he is best known for:

  • Internal medicine
  • Gene
  • Enzyme

Robert M. Senior mostly deals with Matrix metalloproteinase, Molecular biology, Biochemistry, Cell biology and Elastin. His work deals with themes such as Inflammation and Extracellular matrix, which intersect with Matrix metalloproteinase. Robert M. Senior has included themes like Fibronectin, Platelet-derived growth factor, Growth factor, Platelet-derived growth factor receptor and Neutrophil elastase in his Molecular biology study.

Robert M. Senior interconnects Langerhans cell, Fibroblast, Matrix metalloproteinase inhibitor and Cellular differentiation in the investigation of issues within Cell biology. His Cellular differentiation study combines topics from a wide range of disciplines, such as Histiocyte, Endocrinology and Internal medicine. His research investigates the link between Elastin and topics such as Pancreatic elastase that cross with problems in Proteolysis, Pathology, Lung and Leukocyte elastase.

His most cited work include:

  • MMP-9/Gelatinase B Is a Key Regulator of Growth Plate Angiogenesis and Apoptosis of Hypertrophic Chondrocytes (1535 citations)
  • Requirement for Macrophage Elastase for Cigarette Smoke-Induced Emphysema in Mice (1298 citations)
  • Interleukin-13 Induces Tissue Fibrosis by Selectively Stimulating and Activating Transforming Growth Factor β1 (743 citations)

What are the main themes of his work throughout his whole career to date?

His primary scientific interests are in Molecular biology, Matrix metalloproteinase, Cell biology, Immunology and Pathology. His research in Molecular biology intersects with topics in Neutrophil elastase, Messenger RNA, Monocyte, Fibroblast and Cathepsin G. His Matrix metalloproteinase research focuses on Inflammation and how it relates to Immune system.

The concepts of his Cell biology study are interwoven with issues in Chemotaxis and Cellular differentiation. His Chemotaxis research is multidisciplinary, relying on both Endocrinology, Growth factor and Peptide. In Pathology, Robert M. Senior works on issues like Lung, which are connected to Elastin, Disease, Fibrosis and COPD.

He most often published in these fields:

  • Molecular biology (23.58%)
  • Matrix metalloproteinase (21.23%)
  • Cell biology (20.28%)

What were the highlights of his more recent work (between 2005-2017)?

  • Pathology (20.75%)
  • Matrix metalloproteinase (21.23%)
  • Cell biology (20.28%)

In recent papers he was focusing on the following fields of study:

Robert M. Senior focuses on Pathology, Matrix metalloproteinase, Cell biology, Laminin and Immunology. His biological study spans a wide range of topics, including Macrophage and Lung. His Matrix metalloproteinase research includes elements of Cancer research, Viral Myocarditis, Myocarditis, Inflammation and Monocyte.

He is interested in Extracellular matrix, which is a field of Cell biology. His research integrates issues of Epithelial cell differentiation, Molecular biology, Glycoprotein, Basement membrane and Smooth muscle cell differentiation in his study of Laminin. In the subject of general Immunology, his work in Pathogenesis is often linked to Enamel organ, thereby combining diverse domains of study.

Between 2005 and 2017, his most popular works were:

  • Elastin fragments drive disease progression in a murine model of emphysema (386 citations)
  • The Induction of Pulmonary Emphysema with Human Leukocyte Elastase1–3 (287 citations)
  • Fragments of extracellular matrix as mediators of inflammation. (276 citations)

In his most recent research, the most cited papers focused on:

  • Internal medicine
  • Gene
  • Enzyme

The scientist’s investigation covers issues in Pathology, Matrix metalloproteinase, Extracellular matrix, Lung and Molecular biology. His Pathology study combines topics in areas such as Zymography, Macrophage, Proteinuria and Monocyte. His Matrix metalloproteinase research integrates issues from Inflammation, Fibronectin, Type I collagen, Protease and Transforming growth factor.

Cell biology covers he research in Extracellular matrix. His Lung research is multidisciplinary, incorporating perspectives in Pancreatic elastase, Elastin, Human microbiome and Metagenomics. His Molecular biology research incorporates themes from Laminin, Transfection, Matrix metalloproteinase inhibitor, Fibrosis and Fibroblast.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Requirement for Macrophage Elastase for Cigarette Smoke-Induced Emphysema in Mice

R. Dean Hautamaki;Dale K. Kobayashi;Robert M. Senior;Steven D. Shapiro.
Science (1997)

2081 Citations

MMP-9/Gelatinase B Is a Key Regulator of Growth Plate Angiogenesis and Apoptosis of Hypertrophic Chondrocytes

Thiennu H Vu;J.Michael Shipley;Gabriele Bergers;Joel E Berger.
Cell (1998)

1940 Citations

MMP9 induction by vascular endothelial growth factor receptor-1 is involved in lung-specific metastasis.

Sachie Hiratsuka;Kazuhiro Nakamura;Shinobu Iwai;Masato Murakami.
Cancer Cell (2002)

1112 Citations

Interleukin-13 Induces Tissue Fibrosis by Selectively Stimulating and Activating Transforming Growth Factor β1

Chun Geun Lee;Robert J. Homer;Zhou Zhu;Sophie Lanone.
Journal of Experimental Medicine (2001)

1001 Citations

Targeted gene disruption of matrix metalloproteinase-9 (gelatinase B) suppresses development of experimental abdominal aortic aneurysms

Robert Pyo;Jason K. Lee;J. Michael Shipley;John A. Curci.
Journal of Clinical Investigation (2000)

932 Citations

Platelet-derived growth factor and transforming growth factor-beta enhance tissue repair activities by unique mechanisms.

G F Pierce;T A Mustoe;J Lingelbach;V R Masakowski.
Journal of Cell Biology (1989)

761 Citations

Matrix metalloproteinase-9 in lung remodeling.

Jeffrey J. Atkinson;Robert M. Senior.
American Journal of Respiratory Cell and Molecular Biology (2003)

756 Citations

Chemotaxis of monocytes and neutrophils to platelet-derived growth factor.

T F Deuel;R M Senior;J S Huang;G L Griffin.
Journal of Clinical Investigation (1982)

722 Citations

Neutral metalloproteinases produced by human mononuclear phagocytes. Enzyme profile, regulation, and expression during cellular development.

H G Welgus;E J Campbell;J D Cury;A Z Eisen.
Journal of Clinical Investigation (1990)

610 Citations

Chemotactic activity of elastin-derived peptides.

R. M. Senior;G. L. Griffin;Robert Mecham.
Journal of Clinical Investigation (1980)

601 Citations

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