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Biology and Biochemistry

D-Index
93
Citations
33376
World Ranking
2091
National Ranking
1141

Medicine

D-Index
94
Citations
33601
World Ranking
10461
National Ranking
5383

Research.com Recognitions

  • 1987 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Robert M. Senior is affiliated with Washington University in St. Louis in the United States. Their research primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology. The subfields of study include Pathology and Forensic Medicine, Cell Biology, Genetics, Cancer Research, and Hematology.

Their main research topics cover Autoimmune Bullous Skin Diseases, Skin and Cellular Biology Research, Coagulation, Bradykinin, Polyphosphates, and Angioedema, Protease and Inhibitor Mechanisms, and Blood Coagulation and Thrombosis Mechanisms.

Recent publications involve the following works:

  • Neutrophil elastase cleaves the murine hemidesmosomal protein BP180/type XVII collagen and generates degradation products that modulate experimental bullous pemphigoid, 2020, UNC Libraries
  • Synergy between a plasminogen cascade and MMP-9 in autoimmune disease, 2021, UNC Libraries

Frequent collaborators in Robert M. Senior's research include:

  • Zhi Liu
  • Lan Lin
  • Tomoko Betsuyaku
  • Lisa Heimbach
  • Ning Li

The main venue for their publications has been UNC Libraries.

Robert M. Senior was recognized as a Fellow of the American Association for the Advancement of Science (AAAS) in 1987.

Best Publications

  • MMP-9/Gelatinase B Is a Key Regulator of Growth Plate Angiogenesis and Apoptosis of Hypertrophic Chondrocytes

    Thiennu H Vu;J.Michael Shipley;Gabriele Bergers;Joel E Berger

  • Requirement for Macrophage Elastase for Cigarette Smoke-Induced Emphysema in Mice

    R. Dean Hautamaki;Dale K. Kobayashi;Robert M. Senior;Steven D. Shapiro

  • MMP9 induction by vascular endothelial growth factor receptor-1 is involved in lung-specific metastasis.

    Sachie Hiratsuka;Kazuhiro Nakamura;Shinobu Iwai;Masato Murakami

  • Interleukin-13 Induces Tissue Fibrosis by Selectively Stimulating and Activating Transforming Growth Factor β1

    Chun Geun Lee;Robert J. Homer;Zhou Zhu;Sophie Lanone

  • Targeted gene disruption of matrix metalloproteinase-9 (gelatinase B) suppresses development of experimental abdominal aortic aneurysms

    Robert Pyo;Jason K. Lee;J. Michael Shipley;John A. Curci

  • Platelet-derived growth factor and transforming growth factor-beta enhance tissue repair activities by unique mechanisms.

    G F Pierce;T A Mustoe;J Lingelbach;V R Masakowski

  • Matrix metalloproteinase-9 in lung remodeling.

    Jeffrey J. Atkinson;Robert M. Senior

  • Chemotaxis of monocytes and neutrophils to platelet-derived growth factor.

    T F Deuel;R M Senior;J S Huang;G L Griffin

  • Human 92- and 72-kilodalton type IV collagenases are elastases.

    R. M. Senior;G. L. Griffin;C. J. Fliszar;S. D. Shapiro

  • Chemotactic activity of elastin-derived peptides.

    R. M. Senior;G. L. Griffin;Robert Mecham

  • Neutral metalloproteinases produced by human mononuclear phagocytes. Enzyme profile, regulation, and expression during cellular development.

    H G Welgus;E J Campbell;J D Cury;A Z Eisen

  • Platelet Factor 4 Is Chemotactic for Neutrophils and Monocytes

    Thomas F. Deuel;Robert M. Senior;Donald Chang;Gail L. Griffin

  • Targeted Disruption of the Matrix Metalloproteinase-9 Gene Impairs Smooth Muscle Cell Migration and Geometrical Arterial Remodeling

    Zorina S. Galis;Chad Johnson;Denis Godin;Richard Magid

  • The Serpin α1-Proteinase Inhibitor Is a Critical Substrate for Gelatinase B/MMP-9 In Vivo

    Zhi Liu;Xiaoye Zhou;Steven D Shapiro;J.Michael Shipley

  • Elastin fragments drive disease progression in a murine model of emphysema

    A. McGarry Houghton;Pablo A. Quintero;David L. Perkins;Dale K. Kobayashi

  • Chronic Obstructive Pulmonary Disease (COPD)

    Robert M. Senior;Nicholas R. Anthonisen

  • Val-Gly-Val-Ala-Pro-Gly, a repeating peptide in elastin, is chemotactic for fibroblasts and monocytes.

    R M Senior;G L Griffin;R P Mecham;D S Wrenn

  • Fragments of extracellular matrix as mediators of inflammation.

    Tracy L. Adair-Kirk;Robert M. Senior

  • The induction of pulmonary emphysema with human leukocyte elastase.

    Robert M. Senior;Hans Tegner;Charles Kuhn;Kjell Ohlsson

  • Overlapping and enzyme-specific contributions of matrix metalloproteinases-9 and -12 in IL-13–induced inflammation and remodeling

    Sophie Lanone;Tao Zheng;Zhou Zhu;Wei Liu

Frequent Co-Authors

Edward J. Campbell
Edward J. Campbell University of Utah
Steven D. Shapiro
Steven D. Shapiro University of Southern California
Robert P. Mecham
Robert P. Mecham Washington University in St. Louis
Howard G. Welgus
Howard G. Welgus Arcutis Biotherapeutics
Thomas F. Deuel
Thomas F. Deuel Scripps Research Institute
Jeffrey H. Miner
Jeffrey H. Miner Washington University in St. Louis
Zhi Liu
Zhi Liu University of North Carolina at Chapel Hill
William C. Parks
William C. Parks Cedars-Sinai Medical Center
Luis A. Diaz
Luis A. Diaz Memorial Sloan Kettering Cancer Center
Shigeyoshi Itohara
Shigeyoshi Itohara RIKEN Center for Brain Science

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