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Biology and Biochemistry

D-Index
55
Citations
10774
World Ranking
15068
National Ranking
6305

Overview

Charles W. Frevert is affiliated with the University of Washington in the United States. Their research spans several interconnected fields including Medicine, Biochemistry, Genetics and Molecular Biology, and Immunology and Microbiology. The subfields of their work include Immunology, Epidemiology, Cell Biology, Molecular Biology, and Pulmonary and Respiratory Medicine.

Their research topics focus on Proteoglycans and glycosaminoglycans research, Immune Response and Inflammation, Asthma and respiratory diseases, Influenza Virus Research Studies, IL-33, ST2, and ILC Pathways, Cell Adhesion Molecules Research, and Glycosylation and Glycoproteins Research.

Charles W. Frevert has published work in several scientific venues, with multiple publications in the Journal of Histochemistry & Cytochemistry, American Journal of Respiratory and Critical Care Medicine, American Journal of Physiology-Cell Physiology, bioRxiv (Cold Spring Harbor Laboratory), and the American Journal of Respiratory Cell and Molecular Biology.

The scientist has collaborated frequently with a number of coauthors, reflecting ongoing partnerships within their research community. Their frequent collaborators include William A. Altemeier, Mary Y. Chang, J Brune, Teal S. Hallstrand, and Ying Lai.

Representative recent papers authored or co-authored by Charles W. Frevert include:

  • "Versican-A Critical Extracellular Matrix Regulator of Immunity and Inflammation" (2020) published in Frontiers in Immunology
  • "Neutrophil recruitment by chemokines Cxcl1/KC and Cxcl2/MIP2: Role of Cxcr2 activation and glycosaminoglycan interactions" (2020) published in Journal of Leukocyte Biology
  • "CFTR dysregulation drives active selection of the gut microbiome" (2020) published in PLoS Pathogens
  • "Location of eosinophils in the airway wall is critical for specific features of airway hyperresponsiveness and T2 inflammation in asthma" (2022) published in European Respiratory Journal
  • "Distinct Epithelial-Innate Immune Cell Transcriptional Circuits Underlie Airway Hyperresponsiveness in Asthma" (2023) published in American Journal of Respiratory and Critical Care Medicine

Best Publications

  • Animal models of acute lung injury.

    Gustavo Matute-Bello;Charles W. Frevert;Thomas R. Martin

  • Innate immunity in the lungs.

    Thomas R. Martin;Charles W. Frevert

  • Functional characterization of the rat chemokine KC and its importance in neutrophil recruitment in a rat model of pulmonary inflammation.

    C. W. Frevert;Songlih Huang;Hadi Danaee;J. D. Paulauskis

  • Expression and Function of the Chemokine Receptors CXCR1 and CXCR2 in Sepsis

    C J Cummings;T R Martin;C W Frevert;J M Quan

  • Controls for Immunohistochemistry: The Histochemical Society’s Standards of Practice for Validation of Immunohistochemical Assays

    Stephen M. Hewitt;Denis G. Baskin;Charles W. Frevert;William L. Stahl

  • Fas (CD95) induces proinflammatory cytokine responses by human monocytes and monocyte-derived macrophages

    David R. Park;Anni R. Thomsen;Charles W. Frevert;Uyenvy Pham

  • Rapid fluorescence-based measurement of neutrophil migration in vitro.

    C.W Frevert;V.A Wong;R.B Goodman;R Goodwin

  • Duffy Antigen Facilitates Movement of Chemokine Across the Endothelium In Vitro and Promotes Neutrophil Transmigration In Vitro and In Vivo

    Janet S. Lee;Charles W. Frevert;Mark M. Wurfel;Stephen C. Peiper

  • Mechanical Ventilation with Moderate Tidal Volumes Synergistically Increases Lung Cytokine Response to Systemic Endotoxin

    William A. Altemeier;Gustavo Matute-Bello;Charles W. Frevert;Yasunobu Kawata

  • Versican-A Critical Extracellular Matrix Regulator of Immunity and Inflammation

    Thomas N Wight;Inkyung Kang;Stephen P Evanko;Ingrid A Harten

  • Dysregulation of Macrophage Activation Profiles by Engineered Nanoparticles

    Vamsi Kodali;Matthew H. Littke;Susan C. Tilton;Justin G. Teeguarden

  • Essential Role of MMP-12 in Fas-Induced Lung Fibrosis

    Gustavo Matute-Bello;Mark M. Wurfel;Janet S. Lee;David R. Park

  • Binding of interleukin-8 to heparan sulfate and chondroitin sulfate in lung tissue.

    Charles W. Frevert;Michael G. Kinsella;Charie Vathanaprida;Richard B. Goodman

  • Recombinant human Fas ligand induces alveolar epithelial cell apoptosis and lung injury in rabbits.

    Gustavo Matute-Bello;W. Conrad Liles;Charles W. Frevert;Morio Nakamura

  • Proteoglycans: Key Regulators of Pulmonary Inflammation and the Innate Immune Response to Lung Infection

    Sean Gill;Thomas N. Wight;Charles W. Frevert

  • Danger-Associated Molecular Patterns Derived From the Extracellular Matrix Provide Temporal Control of Innate Immunity:

    Charles W. Frevert;Jessica Felgenhauer;Malgorzata Wygrecka;Madalina V. Nastase

  • Functional characterization of rat chemokine macrophage inflammatory protein-2

    Charles W. Frevert;Anthony Farone;Hadi Danaee;Joseph D. Paulauskis

  • Measurement of cell migration in response to an evolving radial chemokine gradient triggered by a microvalve

    Charles W. Frevert;Gregory Boggy;Thomas M. Keenan;Albert Folch

  • Tissue Inhibitor of Metalloproteinase-1 Deficiency Amplifies Acute Lung Injury in Bleomycin-Exposed Mice

    Kyoung Hee Kim;Kristin Burkhart;Peter Chen;Charles W. Frevert

  • Interplay of extracellular matrix and leukocytes in lung inflammation.

    Thomas N. Wight;Charles W. Frevert;Jason S. Debley;Stephen R. Reeves

Frequent Co-Authors

Thomas R. Martin
Thomas R. Martin University of Washington
Thomas N. Wight
Thomas N. Wight Virginia Mason Medical Center
Teal S. Hallstrand
Teal S. Hallstrand University of Washington
W. Conrad Liles
W. Conrad Liles University of Washington
Shawn J. Skerrett
Shawn J. Skerrett University of Washington
William C. Parks
William C. Parks Cedars-Sinai Medical Center
Janet S. Lee
Janet S. Lee University of Pittsburgh
Brian Johnson
Brian Johnson University of Washington
Lester Kobzik
Lester Kobzik Harvard University
Michael H. Gelb
Michael H. Gelb University of Washington

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