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Biology and Biochemistry

D-Index
62
Citations
13136
World Ranking
10847
National Ranking
197

Overview

Mark H. Rider is affiliated with the Université Catholique de Louvain in Belgium. Their research work spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with a significant focus on Physiology and Molecular Biology as subfields. Their scholarly output includes topics related to Metabolism, Diabetes, and Cancer; Pancreatic function and diabetes; Alzheimer's disease research and treatments; Calcium signaling and nucleotide metabolism; Adipose Tissue and Metabolism; Dementia and Cognitive Impairment Research; and Parkinson's Disease Mechanisms and Treatments.

Their recent publication record features several papers across well-known scientific journals. These include:

  • Specific post-translational modifications of soluble tau protein distinguishes Alzheimer's disease and primary tauopathies, 2023, Nature Communications
  • TLR9 and beclin 1 crosstalk regulates muscle AMPK activation in exercise, 2020, Nature
  • Metabolic control by AMPK in white adipose tissue, 2023, Trends in Endocrinology and Metabolism
  • AMPK inhibits liver gluconeogenesis: fact or fiction?, 2023, Biochemical Journal
  • Aberrant Membrane Composition and Biophysical Properties Impair Erythrocyte Morphology and Functionality in Elliptocytosis, 2020, Biomolecules

Mark H. Rider frequently publishes in several specific venues, notably:

  • Biochemical Journal
  • Nature Communications
  • Nature
  • Trends in Endocrinology and Metabolism
  • Biomolecules

Their collaboration network includes co-authors with whom they have published multiple times, such as:

  • Manuel Johanns
  • Didier Vertommen
  • Sébastien Pyr dit Ruys
  • Gaëtan Herinckx
  • Gregory R. Steinberg

Their research covers a wide array of topics, with an emphasis on the molecular mechanisms underlying metabolic regulation and neurological diseases. Several of their papers investigate key aspects of AMPK signaling and its roles in metabolism and exercise. Their work on tau protein modifications contributes to the understanding of Alzheimer's disease and other tauopathies, while other studies explore erythrocyte morphology in pathological states.

Overall, Mark H. Rider's body of work contributes to the intersection of metabolism, molecular biology, and disease mechanisms, published across multidisciplinary journals in medicine and biochemistry.

Best Publications

  • Role of PFKFB3-Driven Glycolysis in Vessel Sprouting

    Katrien De Bock;Maria Georgiadou;Sandra Schoors;Anna Kuchnio

  • Phosphorylation and activation of heart PFK-2 by AMPK has a role in the stimulation of glycolysis during ischaemia.

    A S Marsin;L Bertrand;M H Rider;J Deprez

  • Phosphorylation and activation of heart 6-phosphofructo-2-kinase by protein kinase B and other protein kinases of the insulin signaling cascades

    Johan Deprez;Didier Vertommen;Dario R. Alessi;Louis Hue

  • Activation of AMP-Activated Protein Kinase Leads to the Phosphorylation of Elongation Factor 2 and an Inhibition of Protein Synthesis

    Sandrine Horman;Gareth J. Browne;Ulrike Krause;Jigna V. Patel

  • Role of fructose 2,6-bisphosphate in the control of glycolysis in mammalian tissues.

    Louis Hue;Mark Rider

  • 6-Phosphofructo-2-kinase/fructose-2,6-bisphosphatase: head-to-head with a bifunctional enzyme that controls glycolysis

    Mark H. Rider;Luc Bertrand;Didier Vertommen;Paul A. Michels

  • Insulin Antagonizes Ischemia-induced Thr172 Phosphorylation of AMP-activated Protein Kinase α-Subunits in Heart via Hierarchical Phosphorylation of Ser485/491

    Sandrine Horman;Didier Vertommen;Richard Heath;Dietbert Neumann

  • Identification of phosphorylation sites in AMP-activated protein kinase (AMPK) for upstream AMPK kinases and study of their roles by site-directed mutagenesis.

    Angela Woods;Didier Vertommen;Dietbert Neumann;Roland Türk

  • A Cluster of Mutations in the UMOD Gene Causes Familial Juvenile Hyperuricemic Nephropathy with Abnormal Expression of Uromodulin

    Karin Dahan;Olivier Devuyst;Michèle Smaers;Didier Vertommen

  • Mechanisms of control of heart glycolysis.

    Christophe Depré;Mark H. Rider;Louis Hue

  • Sustained activation of AMP-activated protein kinase induces c-Jun N-terminal kinase activation and apoptosis in liver cells.

    Delphine Meisse;Mark Van de Casteele;Christophe Beauloye;Isabelle Hainault

  • Identification, cloning, and heterologous expression of a mammalian fructosamine-3-kinase.

    Ghislain Delpierre;Mark H. Rider;Francois Collard;Vincent Stroobant

  • Myocardial Ischemia and Increased Heart Work Modulate the Phosphorylation State of Eukaryotic Elongation Factor-2

    Sandrine Horman;Christophe Beauloye;Didier Vertommen;Jean-Louis Vanoverschelde

  • Identification of a dehydrogenase acting on D-2-hydroxyglutarate.

    Younes Achouri;Gaëtane Noël;Didier Vertommen;Mark H. Rider

  • AMPK antagonizes hepatic glucagon-stimulated cyclic AMP signalling via phosphorylation-induced activation of cyclic nucleotide phosphodiesterase 4B

    Manuel Johanns;Y.-C. Lai;M.-F. Hsu;R. Jacobs

  • AMP-activated protein kinase phosphorylates and desensitizes smooth muscle myosin light chain kinase.

    Sandrine Horman;Nicole Morel;Didier Vertommen;Nusrat Hussain

  • Cloning, sequencing and expression of rat liver 3-phosphoglycerate dehydrogenase.

    Younes Achouri;Mark H. Rider;Emile Van Schaftingen;Mariette Robbi

  • Insulin and ischemia stimulate glycolysis by acting on the same targets through different and opposing signaling pathways.

    Louis Hue;Christophe Beauloye;Anne-Sophie Marsin;Luc Bertrand

  • Differential expression of glycosomal and mitochondrial proteins in the two major life-cycle stages of Trypanosoma brucei

    Didier Vertommen;Joris Van Roy;Jean-Pierre Szikora;Mark H. Rider

  • Protein kinase signaling pathway triggered by cell swelling and involved in the activation of glycogen synthase and acetyl-CoA carboxylase in isolated rat hepatocytes.

    Ulrike Krause;Mark H. Rider;Louis Hue

Frequent Co-Authors

Louis Hue
Louis Hue Université Catholique de Louvain
Didier Vertommen
Didier Vertommen Université Catholique de Louvain
Luc Bertrand
Luc Bertrand Université Catholique de Louvain
Benoit Viollet
Benoit Viollet Institut Cochin
Marc Foretz
Marc Foretz Université Paris Cité
Christopher G. Proud
Christopher G. Proud University of Adelaide
Emile Van Schaftingen
Emile Van Schaftingen Université Catholique de Louvain
Guy G. Rousseau
Guy G. Rousseau Université Catholique de Louvain
Paul A. M. Michels
Paul A. M. Michels University of Edinburgh
Bruce E. Kemp
Bruce E. Kemp Australian Catholic University

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