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D-Index & Metrics

Biology and Biochemistry

D-Index
61
Citations
12355
World Ranking
11430
National Ranking
208

Overview

Luc Bertrand is affiliated with the Université Catholique de Louvain in Belgium and has contributed extensively to the fields of Medicine and Biochemistry, Genetics and Molecular Biology. Their research primarily spans several subfields, including Molecular Biology, Cardiology and Cardiovascular Medicine, Physiology, Endocrinology, Diabetes and Metabolism, and Surgery.

Their work covers key topics such as Cardiovascular Function and Risk Factors, Metabolism, Diabetes, and Cancer, Glycosylation and Glycoproteins Research, Adipose Tissue and Metabolism, Galectins and Cancer Biology, Mitochondrial Function and Pathology, and Cardiac Ischemia and Reperfusion.

Luc Bertrand has published numerous articles in various scientific venues. Frequent publication outlets include:

  • Archives of Cardiovascular Diseases Supplements
  • bioRxiv (Cold Spring Harbor Laboratory)
  • International Journal of Molecular Sciences
  • American Journal of Physiology-Heart and Circulatory Physiology
  • Archives of cardiovascular diseases

Several recent papers illustrate the scope and focus of their research. These include:

  • "Cardiac metabolism as a driver and therapeutic target of myocardial infarction" (2020, Journal of Cellular and Molecular Medicine)
  • "Towards standardization of echocardiography for the evaluation of left ventricular function in adult rodents: a position paper of the ESC Working Group on Myocardial Function" (2020, Cardiovascular Research)
  • "IMproving Preclinical Assessment of Cardioprotective Therapies (IMPACT) criteria: guidelines of the EU-CARDIOPROTECTION COST Action" (2021, Basic Research in Cardiology)
  • "AMP-activated protein kinase: A remarkable contributor to preserve a healthy heart against ROS injury" (2021, Free Radical Biology and Medicine)
  • "Effect of hyperglycaemia and diabetes on acute myocardial ischaemia-reperfusion injury and cardioprotection by ischaemic conditioning protocols" (2020, British Journal of Pharmacology)

Collaboration is an important aspect of Luc Bertrand's research, with frequent coauthors including:

  • Christophe Beauloye
  • Sandrine Horman
  • Laurent Bultot
  • Audrey Ginion
  • Caroline Bouzin

The focus on cardiovascular and metabolic research, combined with a strong publication record across relevant journals and multiple collaborative relationships, defines Luc Bertrand's contribution to biomedical sciences.

Best Publications

  • Metformin: From Mechanisms of Action to Therapies

    Marc Foretz;Bruno Guigas;Luc Bertrand;Michael Pollak

  • Phosphorylation and activation of heart PFK-2 by AMPK has a role in the stimulation of glycolysis during ischaemia.

    A S Marsin;L Bertrand;M H Rider;J Deprez

  • Activation of AMP-activated protein kinase in the liver: a new strategy for the management of metabolic hepatic disorders

    Benoit Viollet;Marc Foretz;Bruno Guigas;Sandrine Horman

  • Activation of AMP-Activated Protein Kinase Leads to the Phosphorylation of Elongation Factor 2 and an Inhibition of Protein Synthesis

    Sandrine Horman;Gareth J. Browne;Ulrike Krause;Jigna V. Patel

  • 6-Phosphofructo-2-kinase/fructose-2,6-bisphosphatase: head-to-head with a bifunctional enzyme that controls glycolysis

    Mark H. Rider;Luc Bertrand;Didier Vertommen;Paul A. Michels

  • The stimulation of glycolysis by hypoxia in activated monocytes is mediated by AMP-activated protein kinase and inducible 6-phosphofructo-2-kinase.

    Anne-Sophie Marsin;Caroline Bouzin;Luc Bertrand;Louis Hue

  • Cloning and functional characterization of a cocaine-sensitive dopamine transporter.

    Bruno Giros;Salah El Mestikawy;Lucie Bertrand;Marc G. Caron

  • AMPK: Lessons from transgenic and knockout animals.

    Benoit Viollet;Yoni Athea;Remi Mounier;Bruno Guigas

  • Insulin signalling in the heart

    Luc Bertrand;Sandrine Horman;Christophe Beauloye;Jean-Louis Vanoverschelde

  • Deficiency of LKB1 in heart prevents ischemia-mediated activation of AMPKalpha2 but not AMPKalpha1.

    Kei Sakamoto;Elham Zarrinpashneh;Grant R. Budas;Anne-Catherine Pouleur

  • 5-Aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside and metformin inhibit hepatic glucose phosphorylation by an AMP-activated protein kinase-independent effect on glucokinase translocation.

    Bruno Guigas;Luc Bertrand;Nellie Taleux;Marc Foretz

  • Deficiency of PDK1 in cardiac muscle results in heart failure and increased sensitivity to hypoxia

    Alfonso Mora;Anthony M. Davies;Luc Bertrand;Isam Sharif

  • AMPK activation, a preventive therapeutic target in the transition from cardiac injury to heart failure.

    Christophe Beauloye;Luc Bertrand;Sandrine Horman;Louis Hue

  • Control of p70 ribosomal protein S6 kinase and acetyl-CoA carboxylase by AMP-activated protein kinase and protein phosphatases in isolated hepatocytes

    Ulrike Krause;Luc Bertrand;Louis Hue

  • AMPK activation counteracts cardiac hypertrophy by reducing O-GlcNAcylation.

    Roselle Gélinas;Florence Mailleux;Justine Dontaine;Laurent Bultot

  • The BRET2/arrestin assay in stable recombinant cells: a platform to screen for compounds that interact with G protein-coupled receptors (GPCRS).

    Lucie Bertrand;Stéphane Parent;Mireille Caron;Mireille Legault

  • AMPK activation restores the stimulation of glucose uptake in an in vitro model of insulin-resistant cardiomyocytes via the activation of protein kinase B

    Luc Bertrand;Audrey Ginion;Christophe Beauloye;Alexandre D. Hebert

  • Enhanced Expression of β3-Adrenoceptors in Cardiac Myocytes Attenuates Neurohormone-Induced Hypertrophic Remodeling Through Nitric Oxide Synthase

    Catharina Belge;Joanna Hammond;Emilie Dubois-Deruy;Boris Manoury

  • Insulin antagonizes AMP-activated protein kinase activation by ischemia or anoxia in rat hearts, without affecting total adenine nucleotides.

    Christophe Beauloye;Anne-Sophie Marsin;Luc Bertrand;Ulrike Krause

  • Cardiac metabolism as a driver and therapeutic target of myocardial infarction.

    Coert J. Zuurbier;Luc Bertrand;Christoph R. Beauloye;Christoph R. Beauloye;Ioanna Andreadou

Frequent Co-Authors

Jean-Louis Vanoverschelde
Jean-Louis Vanoverschelde Université Catholique de Louvain
Louis Hue
Louis Hue Université Catholique de Louvain
Benoit Viollet
Benoit Viollet Institut Cochin
Didier Vertommen
Didier Vertommen Université Catholique de Louvain
Mark H. Rider
Mark H. Rider Université Catholique de Louvain
Marc Foretz
Marc Foretz Université Paris Cité
Kei Sakamoto
Kei Sakamoto University of Copenhagen
Dario R. Alessi
Dario R. Alessi University of Dundee
Simon J. Conway
Simon J. Conway Indiana University
Bruce E. Kemp
Bruce E. Kemp Australian Catholic University

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