What is he best known for?
The fields of study he is best known for:
His primary areas of investigation include Genetics, Leukemia, Mutation, Myeloid and Myeloid leukemia.
Timothy J. Ley works mostly in the field of Genetics, limiting it down to concerns involving Computational biology and, occasionally, Medical genetics.
His Leukemia research is multidisciplinary, incorporating perspectives in Cancer research, Stem cell, Promyelocytic leukemia protein and Somatic evolution in cancer.
His Cancer research study combines topics from a wide range of disciplines, such as Acute promyelocytic leukemia, Cancer, Lymphokine-activated killer cell and Neuroblastoma RAS viral oncogene homolog.
His research in Myeloid intersects with topics in Haematopoiesis, Methyltransferase, Clone and DNA methylation.
His Myeloid leukemia study combines topics in areas such as Enasidenib, Clonal architecture, NPM1 and Oncology.
His most cited work include:
- The cancer genome atlas pan-cancer analysis project (3506 citations)
- Genomic and epigenomic landscapes of adult de novo acute myeloid leukemia (2799 citations)
- Mutational landscape and significance across 12 major cancer types (2600 citations)
What are the main themes of his work throughout his whole career to date?
The scientist’s investigation covers issues in Molecular biology, Gene, Leukemia, Genetics and Cancer research.
Timothy J. Ley combines subjects such as Gene expression, DNA methylation, Cytotoxic T cell, Granzyme B and Globin with his study of Molecular biology.
His study in Leukemia is interdisciplinary in nature, drawing from both Myeloid, Haematopoiesis, Myeloid leukemia and Acute promyelocytic leukemia.
His study looks at the intersection of Myeloid and topics like Gene expression profiling with Transcriptome.
His research investigates the link between Haematopoiesis and topics such as Bone marrow that cross with problems in Oncology.
Genome, Mutation, Whole genome sequencing, Human genome and Genomics are among the areas of Genetics where the researcher is concentrating his efforts.
He most often published in these fields:
- Molecular biology (31.31%)
- Gene (23.99%)
- Leukemia (24.49%)
What were the highlights of his more recent work (between 2013-2021)?
- Cancer research (20.96%)
- Leukemia (24.49%)
- Internal medicine (11.11%)
In recent papers he was focusing on the following fields of study:
Timothy J. Ley mainly focuses on Cancer research, Leukemia, Internal medicine, Oncology and Myeloid leukemia.
The study incorporates disciplines such as DNA methylation, RNA, microRNA, Metastasis and Promyelocytic leukemia protein in addition to Cancer research.
His Leukemia research incorporates themes from Haematopoiesis, Karyotype, Transplantation, Myeloid and Polymerase chain reaction.
The various areas that Timothy J. Ley examines in his Oncology study include Cancer, Somatic evolution in cancer, Azacitidine, Decitabine and Myelodysplastic syndromes.
His work carried out in the field of Myeloid leukemia brings together such families of science as Clonal architecture, CD34, Primary tumor, Peripheral blood and DNA sequencing.
His Exome sequencing research entails a greater understanding of Genetics.
Between 2013 and 2021, his most popular works were:
- Age-related mutations associated with clonal hematopoietic expansion and malignancies (978 citations)
- Role of TP53 mutations in the origin and evolution of therapy-related acute myeloid leukaemia (410 citations)
- TP53 and Decitabine in Acute Myeloid Leukemia and Myelodysplastic Syndromes (399 citations)
In his most recent research, the most cited papers focused on:
Leukemia, Genetics, Myeloid, Myeloid leukemia and Mutation are his primary areas of study.
His Leukemia research incorporates elements of Progenitor cell, Haematopoiesis and Disease.
As a part of the same scientific family, he mostly works in the field of Haematopoiesis, focusing on Gene and, on occasion, Adenocarcinoma.
His Myeloid research is multidisciplinary, incorporating elements of Exome sequencing, Chemotherapy, Induction chemotherapy, Oncology and Bone marrow.
His Myeloid leukemia research is multidisciplinary, relying on both Breast cancer and Clonal architecture, Somatic cell.
The study incorporates disciplines such as Molecular biology, Cancer research and DNA methylation, DNA methyltransferase in addition to Mutation.
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