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Biology and Biochemistry

D-Index
68
Citations
24364
World Ranking
7647
National Ranking
3480

Overview

Allyn C. Howlett is affiliated with Wake Forest University in the United States. Their research focuses primarily on the fields of Medicine, Neuroscience, and Biochemistry, Genetics and Molecular Biology, with particular contributions in Pharmacology, Cellular and Molecular Neuroscience, and Molecular Biology. Their work intersects with related subfields such as Surgery and Pediatrics, Perinatology and Child Health.

The scientist's research spans several main topics, including Cannabis and Cannabinoid Research, Neuroscience and Neuropharmacology Research, Neurotransmitter Receptor Influence on Behavior, Receptor Mechanisms and Signaling, Pancreatic Function and Diabetes, Prenatal Substance Exposure Effects, and Pharmacological Receptor Mechanisms and Effects.

Frequent coauthors of Allyn C. Howlett include Sandra Leone-Kabler, Khalil Eldeeb, W. Todd Lowther, Erin K. Hughes, and John W. Huffman.

Their research has been published multiple times in several distinguished venues, with the most frequent publication outlets including the Journal of Pharmacology and Experimental Therapeutics, The FASEB Journal, Molecules, Journal of Biological Chemistry, and Cannabis and Cannabinoid Research.

Selected recent papers authored or coauthored by Howlett include:

  • "Goods and Bads of the Endocannabinoid System as a Therapeutic Target: Lessons Learned after 30 Years," 2023, Pharmacological Reviews
  • "Endocannabinoid System in Pregnancy Maintenance and Labor: A Mini-Review," 2021, Frontiers in Endocrinology
  • "Cannabinoid Receptor Interacting Protein 1a (CRIP1a) in Health and Disease," 2020, Biomolecules
  • "The Spicy Story of Cannabimimetic Indoles," 2021, Molecules
  • "CB1 Cannabinoid Receptors Stimulate Gβγ-GRK2-Mediated FAK Phosphorylation at Tyrosine 925 to Regulate ERK Activation Involving Neuronal Focal Adhesions," 2020, Frontiers in Cellular Neuroscience

Best Publications

  • International Union of Pharmacology. XXVII. Classification of Cannabinoid Receptors

    A C Howlett;F Barth;T I Bonner;G Cabral

  • Determination and characterization of a cannabinoid receptor in rat brain.

    W A Devane;F A Dysarz;M R Johnson;L S Melvin

  • International Union of Basic and Clinical Pharmacology. LXXIX. Cannabinoid Receptors and Their Ligands: Beyond CB1 and CB2

    Roger Guy Pertwee;A. C. Howlett;M. E. Abood;S. P. H. Alexander

  • Cannabinoid physiology and pharmacology: 30 years of progress

    Allyn C. Howlett;Allyn C. Howlett;Christopher S. Breivogel;Steven R. Childers;Samuel A. Deadwyler

  • Pharmacology of cannabinoid receptors

    Allyn C. Howlett

  • The cannabinoid receptors.

    Allyn C Howlett

  • Reconstitution of hormone-sensitive adenylate cyclase activity with resolved components of the enzyme.

    E M Ross;A C Howlett;K M Ferguson;A G Gilman

  • Cannabinoid receptor signaling

    Howlett Ac

  • The cannabinoid receptor: biochemical, anatomical and behavioral characterization

    Allyn C Howlett;Michelle Bidaut-Russell;William A Devane;Lawrence S Melvin

  • Early phytocannabinoid chemistry to endocannabinoids and beyond

    Raphael Mechoulam;Lumír O. Hanuš;Roger Pertwee;Allyn C. Howlett

  • Cannabinoid receptor binding and messenger RNA expression in human brain: An in vitro receptor autoradiography and in situ hybridization histochemistry study of normal aged and Alzheimer's brains

    T.M. Westlake;A.C. Howlett;T.I. Bonner;L.A. Matsuda

  • Cannabinoid inhibition of adenylate cyclase. Biochemistry of the response in neuroblastoma cell membranes.

    A C Howlett

  • CB1 Cannabinoid Receptors and their Associated Proteins

    Allyn C. Howlett;Lawrence C. Blume;George D. Dalton

  • Nonclassical cannabinoid analgetics inhibit adenylate cyclase: development of a cannabinoid receptor model.

    A C Howlett;M R Johnson;L S Melvin;G M Milne

  • CB1 and CB2 Receptor Pharmacology

    Allyn C. Howlett;Mary E. Abood

  • Cellular signal transduction by anandamide and 2-arachidonoylglycerol

    Allyn C Howlett;Somnath Mukhopadhyay

  • Cannabinoid receptors and modulation of cyclic AMP accumulation in the rat brain.

    Michelle Bidaut‐Russell;William A. Devane;Allyn C. Howlett

  • Inhibitors of arachidonoyl ethanolamide hydrolysis.

    Bohumir Koutek;Glenn D. Prestwich;Allyn C. Howlett;Suzette A. Chin

  • Methyl arachidonyl fluorophosphonate: a potent irreversible inhibitor of anandamide amidase

    Dale G. Deutsch;Romelda Omeir;Gladys Arreaza;David Salehani

  • The ontogeny of cannabinoid receptors in the brain of postnatal and aging rats.

    Rusoun C. Belue;Allyn C. Howlett;Tracy M. Westlake;Donald E. Hutchings

Frequent Co-Authors

Debra I. Diz
Debra I. Diz Wake Forest University
Steven R. Childers
Steven R. Childers Wake Forest University
Alfred G. Gilman
Alfred G. Gilman The University of Texas Southwestern Medical Center
Raphael Mechoulam
Raphael Mechoulam Hebrew University of Jerusalem
Roger G. Pertwee
Roger G. Pertwee University of Aberdeen
Miles Herkenham
Miles Herkenham National Institutes of Health
Kenner C. Rice
Kenner C. Rice National Institutes of Health
Elliott M. Ross
Elliott M. Ross The University of Texas Southwestern Medical Center
Ken Mackie
Ken Mackie Indiana University
Robert E. Hampson
Robert E. Hampson Wake Forest University

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