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Genetics

D-Index
70
Citations
27262
World Ranking
2242
National Ranking
1009

Research.com Recognitions

  • 2014 - Fellow of the American Academy of Arts and Sciences
  • 2014 - Member of the National Academy of Sciences

Overview

Shiv I. S. Grewal is affiliated with the National Institutes of Health in the United States. Their research primarily spans the fields of Biochemistry, Genetics, and Molecular Biology, with a particular focus on Molecular Biology at the subfield level.

Their scientific work covers several main topics, including:

  • Genomics and Chromatin Dynamics
  • Epigenetics and DNA Methylation
  • RNA modifications and cancer
  • RNA Research and Splicing
  • Cancer-related gene regulation
  • Pneumocystis jirovecii pneumonia detection and treatment
  • Fungal Infections and Studies

Their publication record includes papers in prominent venues such as Molecular Cell, Proceedings of the National Academy of Sciences, Nature Structural & Molecular Biology, Nature Cell Biology, bioRxiv (Cold Spring Harbor Laboratory), Nature Communications, and Nucleic Acids Research.

Noteworthy recent publications include:

  • The molecular basis of heterochromatin assembly and epigenetic inheritance (2023) in Molecular Cell
  • Spreading and epigenetic inheritance of heterochromatin require a critical density of histone H3 lysine 9 tri-methylation (2021) in Proceedings of the National Academy of Sciences
  • Histone deacetylation primes self-propagation of heterochromatin domains to promote epigenetic inheritance (2022) in Nature Structural & Molecular Biology
  • TOR targets an RNA processing network to regulate facultative heterochromatin, developmental gene expression and cell proliferation (2021) in Nature Cell Biology
  • Nucleosome remodeler exclusion by histone deacetylation enforces heterochromatic silencing and epigenetic inheritance (2024) in Molecular Cell

Frequent collaborators in their publications include David Wheeler, Jothy Dhakshnamoorthy, Martin Zofall, H. Diego Folco, and Sahana Holla, all of whom have contributed multiple times alongside Grewal.

The most common venues for their work are bioRxiv (Cold Spring Harbor Laboratory), Molecular Cell, Proceedings of the National Academy of Sciences, Nature Communications, and Nucleic Acids Research.

The scientist has been recognized with several honors, including election as a Fellow of the American Academy of Arts and Sciences in 2014 and membership in the National Academy of Sciences granted in the same year.

Best Publications

  • Regulation of heterochromatic silencing and histone H3 lysine-9 methylation by RNAi.

    Thomas A. Volpe;Catherine Kidner;Ira M. Hall;Ira M. Hall;Grace Teng;Grace Teng

  • Role of Histone H3 Lysine 9 Methylation in Epigenetic Control of Heterochromatin Assembly

    Jun-ichi Nakayama;Judd C. Rice;Brian D. Strahl;C. David Allis

  • RNAi-Mediated Targeting of Heterochromatin by the RITS Complex

    André Verdel;Songtao Jia;Scott Gerber;Tomoyasu Sugiyama

  • Heterochromatin and Epigenetic Control of Gene Expression

    Shiv I. S. Grewal;Danesh Moazed

  • Establishment and Maintenance of a Heterochromatin Domain

    Ira M. Hall;Gurumurthy D. Shankaranarayana;Ken ichi Noma;Nabieh Ayoub

  • Transitions in Distinct Histone H3 Methylation Patterns at the Heterochromatin Domain Boundaries

    Ken-ichi Noma;C. David Allis;Shiv I. S. Grewal

  • Comprehensive analysis of heterochromatin- and RNAi-mediated epigenetic control of the fission yeast genome

    Hugh P Cam;Tomoyasu Sugiyama;Ee Sin Chen;Xi Chen

  • Recruitment of cohesin to heterochromatic regions by Swi6/HP1 in fission yeast

    Nobuhiro Nonaka;Tomoya Kitajima;Shihori Yokobayashi;Guoping Xiao

  • Transcription and RNA interference in the formation of heterochromatin

    Shiv I. S. Grewal;Sarah C. R. Elgin

  • Heterochromatin: new possibilities for the inheritance of structure.

    Shiv I.S Grewal;Sarah C.R Elgin

  • RITS acts in cis to promote RNA interference-mediated transcriptional and post-transcriptional silencing.

    Ken-ichi Noma;Tomoyasu Sugiyama;Hugh Cam;Andre Verdel

  • Trimethylated lysine 9 of histone H3 is a mark for DNA methylation in Neurospora crassa.

    Hisashi Tamaru;Xing Zhang;Debra McMillen;Prim B. Singh

  • SHREC, an Effector Complex for Heterochromatic Transcriptional Silencing

    Tomoyasu Sugiyama;Hugh P. Cam;Rie Sugiyama;Ken-ichi Noma

  • RNAi-independent heterochromatin nucleation by the stress-activated ATF/CREB family proteins.

    Songtao Jia;Ken-ichi Noma;Shiv I. S. Grewal

  • Roles of the Clr4 methyltransferase complex in nucleation, spreading and maintenance of heterochromatin.

    Ke Zhang;Kerstin Mosch;Wolfgang Fischle;Shiv I S Grewal

  • Cell cycle control of centromeric repeat transcription and heterochromatin assembly

    Ee Sin Chen;Ke Zhang;Estelle Nicolas;Hugh P. Cam

  • Conservation and Rewiring of Functional Modules Revealed by an Epistasis Map in Fission Yeast

    Assen Roguev;Sourav Bandyopadhyay;Martin Zofall;Ke Zhang

  • RNA interference machinery regulates chromosome dynamics during mitosis and meiosis in fission yeast

    Ira M. Hall;Ken-ichi Noma;Shiv I. S. Grewal

  • RNA-dependent RNA polymerase is an essential component of a self-enforcing loop coupling heterochromatin assembly to siRNA production

    Tomoyasu Sugiyama;Hugh Cam;André Verdel;Danesh Moazed

  • A Role for TFIIIC Transcription Factor Complex in Genome Organization

    Ken-ichi Noma;Hugh P. Cam;Richard J. Maraia;Shiv I.S. Grewal

Frequent Co-Authors

Ke Zhang
Ke Zhang Hohai University
Jun-ichi Nakayama
Jun-ichi Nakayama National Institute for Basic Biology
Ming Zhou
Ming Zhou Science Applications International Corporation (United States)
Ryuji Kobayashi
Ryuji Kobayashi The University of Texas MD Anderson Cancer Center
Danesh Moazed
Danesh Moazed Harvard University
Karl Ekwall
Karl Ekwall Karolinska Institute
Sarah C. R. Elgin
Sarah C. R. Elgin Washington University in St. Louis
Job Dekker
Job Dekker University of Massachusetts Chan Medical School
Nevan J. Krogan
Nevan J. Krogan University of California, San Francisco

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