World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
84
Citations
22560
World Ranking
3368
National Ranking
1693

Overview

Dean G. Tang is affiliated with the Roswell Park Cancer Institute in the United States. Their primary research focus spans the fields of Biochemistry, Genetics and Molecular Biology, and Medicine, with significant contributions to Molecular Biology, Pulmonary and Respiratory Medicine, Oncology, Cancer Research, and Cell Biology.

Their recent published papers cover a range of topics related to cancer biology and prostate cancer research. Notable works include:

  • "MicroRNA-34a: Potent Tumor Suppressor, Cancer Stem Cell Inhibitor, and Potential Anticancer Therapeutic" (2021), published in Frontiers in Cell and Developmental Biology
  • "Intron retention is a hallmark and spliceosome represents a therapeutic vulnerability in aggressive prostate cancer" (2020), published in Nature Communications
  • "Androgen receptor (AR) heterogeneity in prostate cancer and therapy resistance" (2021), published in Cancer Letters
  • "Slow-cycling (dormant) cancer cells in therapy resistance, cancer relapse and metastasis" (2021), published in Seminars in Cancer Biology
  • "Understanding and targeting prostate cancer cell heterogeneity and plasticity" (2021), published in Seminars in Cancer Biology

Their research topics are focused on prostate cancer treatment and research, cancer cells and metastasis, microRNA in disease regulation, RNA research and splicing, ubiquitin and proteasome pathways, cancer-related gene regulation, and cancer genomics and diagnostics.

Dean G. Tang has frequently published in venues such as bioRxiv (Cold Spring Harbor Laboratory), Seminars in Cancer Biology, Cancer Research, Cancer Heterogeneity and Plasticity, and Nature Communications.

Collaborations are a significant aspect of their work, with frequent co-authors including Xiaozhuo Liu, Amanda Tracz, Anmbreen Jamroze, Jason Kirk, and Gurkamal Chatta.

Best Publications

  • The microRNA miR-34a inhibits prostate cancer stem cells and metastasis by directly repressing CD44

    Can Liu;Kevin Kelnar;Bigang Liu;Xin Chen

  • Side Population Is Enriched in Tumorigenic, Stem-Like Cancer Cells, whereas ABCG2+ and ABCG2− Cancer Cells Are Similarly Tumorigenic

    Lubna Patrawala;Tammy Calhoun;Robin Schneider-Broussard;Jianjun Zhou;Jianjun Zhou

  • Highly purified CD44 + prostate cancer cells from xenograft human tumors are enriched in tumorigenic and metastatic progenitor cells

    L. Patrawala;T. Calhoun;R. Schneider-Broussard;H. Li

  • Understanding cancer stem cell heterogeneity and plasticity.

    Dean G Tang

  • NANOG promotes cancer stem cell characteristics and prostate cancer resistance to androgen deprivation

    Collene R. Jeter;Bigang Liu;Xin Liu;Xin Liu;Xin-Xin Chen

  • Hierarchical Organization of Prostate Cancer Cells in Xenograft Tumors: The CD44+α2β1+ Cell Population Is Enriched in Tumor-Initiating Cells

    Lubna Patrawala;Tammy Calhoun-Davis;Robin Schneider-Broussard;Dean G. Tang

  • Functional evidence that the self-renewal gene NANOG regulates human tumor development.

    Collene R. Jeter;Mark Badeaux;Grace Choy;Dhyan Chandra

  • Arachidonate lipoxygenases as essential regulators of cell survival and apoptosis

    Dean G. Tang;Yong Q. Chen;Kenneth V. Honn;Kenneth V. Honn

  • Platelets and cancer metastasis: a causal relationship?

    Kenneth V. Honn;Dean G. Tang;John D. Crissman

  • The PSA(-/lo) prostate cancer cell population harbors self-renewing long-term tumor-propagating cells that resist castration.

    Jichao Qin;Xin Liu;Xin Liu;Brian Laffin;Xin Chen;Xin Chen

  • Adhesion molecules and tumor cell interaction with endothelium and subendothelial matrix.

    Kenneth V. Honn;Dean G. Tang

  • Cytosolic Accumulation of HSP60 during Apoptosis with or without Apparent Mitochondrial Release: EVIDENCE THAT ITS PRO-APOPTOTIC OR PRO-SURVIVAL FUNCTIONS INVOLVE DIFFERENTIAL INTERACTIONS WITH CASPASE-3*

    Dhyan Chandra;Grace Choy;Dean G. Tang

  • Prostate cancer stem/progenitor cells: identification, characterization, and implications.

    Dean G. Tang;Lubna Patrawala;Tammy Calhoun;Bobby Bhatia

  • Lack of replicative senescence in cultured rat oligodendrocyte precursor cells.

    Dean G. Tang;Yasuhito M. Tokumoto;James A. Apperly;Alison C. Lloyd

  • MicroRNA Regulation of Cancer Stem Cells

    Can Liu;Dean G. Tang

  • PC3 Human Prostate Carcinoma Cell Holoclones Contain Self-renewing Tumor-Initiating Cells

    Hangwen Li;Xin Chen;Tammy Calhoun-Davis;Kent Claypool

  • Cancer stem cells and radioresistance

    Kiera Rycaj;Dean G. Tang

  • Cell-of-Origin of Cancer versus Cancer Stem Cells: Assays and Interpretations

    Kiera Rycaj;Dean G. Tang;Dean G. Tang

  • Conditional reprogramming and long-term expansion of normal and tumor cells from human biospecimens

    Xuefeng Liu;Ewa Krawczyk;Frank A Suprynowicz;Nancy Palechor-Ceron

  • 12-lipoxygenases and 12(S)-HETE: role in cancer metastasis

    Kenneth V. Honn;Kenneth V. Honn;Dean G. Tang;Xiang Gao;Igor A. Butovich

Frequent Co-Authors

Kenneth V. Honn
Kenneth V. Honn Wayne State University
Xin Liu
Xin Liu Chinese Academy of Sciences
John D. Taylor
John D. Taylor Wayne State University
Jianjun Shen
Jianjun Shen The University of Texas MD Anderson Cancer Center
Yue Lu
Yue Lu The University of Texas MD Anderson Cancer Center
Clement A. Diglio
Clement A. Diglio Wayne State University
Yong Q. Chen
Yong Q. Chen Jiangnan University
Jiaoti Huang
Jiaoti Huang Duke University
Martin Raff
Martin Raff University College London
Richard K. Severson
Richard K. Severson Wayne State University

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Best Scientists Citing Dean G. Tang

Trending Scientists

Recently Published Articles