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Medicine

D-Index
76
Citations
19360
World Ranking
18853
National Ranking
9396

Overview

Simon W. Hayward is affiliated with NorthShore University HealthSystem in the United States. Their research spans multiple fields of study, notably Medicine and Biochemistry, Genetics and Molecular Biology. Within these disciplines, Hayward has focused on several subfields including Pulmonary and Respiratory Medicine, Immunology, Oncology, Molecular Biology, and Urology.

The main topics of Hayward's work are concentrated around prostate-related research and cancer biology. Key areas include:

  • Prostate Cancer Diagnosis and Treatment
  • Prostate Cancer Treatment and Research
  • Urinary Bladder and Prostate Research
  • Hormonal and Reproductive Studies
  • Cancer Cells and Metastasis
  • Cancer Immunotherapy and Biomarkers
  • Immune Cells in Cancer

Hayward has frequently published in venues such as bioRxiv (Cold Spring Harbor Laboratory), The Journal of Urology, European Urology Open Science, Cancers, and Frontiers in Immunology. The scientist has authored multiple research articles, including the following recent papers:

  • "TNF is a potential therapeutic target to suppress prostatic inflammation and hyperplasia in autoimmune disease," 2022, Nature Communications
  • "Stromal reactivity differentially drives tumour cell evolution and prostate cancer progression," 2020, Nature Ecology & Evolution
  • "Deconstructing tumor heterogeneity: the stromal perspective," 2020, Oncotarget
  • "Propagation of human prostate tissue from induced pluripotent stem cells," 2020, Stem Cells Translational Medicine
  • "Fibroblast heterogeneity in prostate carcinogenesis," 2021, Cancer Letters

Throughout their career, Hayward has frequently collaborated with several coauthors, including Omar E. Franco, Renee E. Vickman, Brian T. Helfand, Nadia A. Lanman, and Susan E. Crawford. These collaborations have contributed to advancing the understanding of prostate cancer biology and related medical research.

Best Publications

  • Carcinoma-associated fibroblasts direct tumor progression of initiated human prostatic epithelium.

    Aria F. Olumi;Gary D. Grossfeld;Simon W. Hayward;Peter R. Carroll

  • NTP‐CERHR expert panel report on the reproductive and developmental toxicity of bisphenol A

    Robert E. Chapin;Jane Adams;Kim Boekelheide;L. Earl Gray

  • Cancer-associated fibroblasts promote directional cancer cell migration by aligning fibronectin

    Begum Erdogan;Mingfang Ao;Lauren M. White;Anna L. Means

  • Role of the stromal microenvironment in carcinogenesis of the prostate.

    Gerald R. Cunha;Simon W. Hayward;Y.Z. Wang;William A. Ricke

  • Cancer associated fibroblasts in cancer pathogenesis

    Omar E. Franco;Aubie K. Shaw;Douglas W. Strand;Simon W. Hayward;Simon W. Hayward

  • Establishment and characterization of an immortalized but non-transformed human prostate epithelial cell line: BPH-1

    S. W. Hayward;R. Dahiya;G. R. Cunha;J. Bartek

  • Malignant Transformation in a Nontumorigenic Human Prostatic Epithelial Cell Line

    Simon W. Hayward;Yuzhuo Wang;Mei Cao;Yun Kit Hom

  • Hormonal, cellular, and molecular regulation of normal and neoplastic prostatic development.

    Gerald R Cunha;William A Ricke;Axel Thomson;Paul C Marker

  • Cell differentiation lineage in the prostate

    Yuzhuo Wang;Simon W. Hayward;Mei Cao;Kristina A. Thayer

  • Role of stroma in carcinogenesis of the prostate.

    Gerald R. Cunha;Simon W. Hayward;Y. Z. Wang

  • Loss of TGF-β type II receptor in fibroblasts promotes mammary carcinoma growth and invasion through upregulation of TGF-α-, MSP- and HGF-mediated signaling networks

    Nikki Cheng;Neil A Bhowmick;Anna Chytil;Agnieszka E Gorksa

  • Cross-talk between Paracrine-Acting Cytokine and Chemokine Pathways Promotes Malignancy in Benign Human Prostatic Epithelium

    Mingfang Ao;Omar E. Franco;Dean Park;Dayanidhi Raman

  • Regeneration of Bladder Urothelium, Smooth Muscle, Blood Vessels and Nerves Into an Acellular Tissue Matrix

    Ronald S. Sutherland;Laurence S. Baskin;Simon W. Hayward;Gerald R. Cunha

  • Nkx3.1 Mutant Mice Recapitulate Early Stages of Prostate Carcinogenesis

    Minjung J. Kim;Rajula Bhatia-Gaur;Whitney A. Banach-Petrosky;Nishita Desai

  • The prostate: development and physiology.

    Simon W. Hayward;Gerald R. Cunha

  • Stromal–epithelial interactions in the normal and neoplastic prostate

    S.W. Hayward;M.A. Rosen;G.R. Cunha

  • Interactions between adult human prostatic epithelium and rat urogenital sinus mesenchyme in a tissue recombination model

    Simon W. Hayward;Peter C. Haughney;Mark A. Rosen;Karin M. Greulich

  • Smooth muscle-epithelial interactions in normal and neoplastic prostatic development.

    G.R. Cunha;S.W. Hayward;R. Dahiya;B.A. Foster

  • The Consequences of Chromosomal Aneuploidy on Gene Expression Profiles in a Cell Line Model for Prostate Carcinogenesis

    John L. Phillips;Simon W. Hayward;Yuzhuo Wang;James Vasselli

  • Forkhead box A1 regulates prostate ductal morphogenesis and promotes epithelial cell maturation

    Nan Gao;Kenichiro Ishii;Janni Mirosevich;Satoru Kuwajima

Frequent Co-Authors

Gerald R. Cunha
Gerald R. Cunha University of California, San Francisco
Robert J. Matusik
Robert J. Matusik Vanderbilt University Medical Center
Neil A. Bhowmick
Neil A. Bhowmick Cedars-Sinai Medical Center
Laurence S. Baskin
Laurence S. Baskin University of California, San Francisco
Yuzhuo Wang
Yuzhuo Wang University of British Columbia
Rajvir Dahiya
Rajvir Dahiya University of California, San Francisco
Alexander R. A. Anderson
Alexander R. A. Anderson Moffitt Cancer Center
Ian G. Mills
Ian G. Mills University of Oxford
Thea D. Tlsty
Thea D. Tlsty University of California, San Francisco
Mark L. Day
Mark L. Day University of Michigan–Ann Arbor

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