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Biology and Biochemistry

D-Index
58
Citations
17516
World Ranking
12958
National Ranking
5521

Overview

Neil A. Bhowmick is affiliated with Cedars-Sinai Medical Center in the United States. Their research spans multiple disciplines primarily within Medicine and Biochemistry, Genetics and Molecular Biology. Some of the main subfields they have contributed to include Molecular Biology, Oncology, Pulmonary and Respiratory Medicine, Cancer Research, and Physiology.

Their scientific work addresses a variety of topics with a significant focus on cancer and related biological processes. The main topics of their research include:

  • Prostate Cancer Treatment and Research
  • Cancer, Hypoxia, and Metabolism
  • Epigenetics and DNA Methylation
  • Pancreatic and Hepatic Oncology Research
  • Cancer-related gene regulation
  • RNA modifications and cancer
  • Cancer, Lipids, and Metabolism

Neil A. Bhowmick has published numerous articles across several journals, with frequent appearances in these publication venues:

  • Journal of Biological Chemistry
  • Journal of Clinical Oncology
  • Cancer Research
  • Cancers
  • Endocrine Related Cancer

Their recent papers illustrate the range and focus of their work:

  • "Extracellular vesicles in fatty liver promote a metastatic tumor microenvironment," 2023, Cell Metabolism
  • "COVID-19 and androgen-targeted therapy for prostate cancer patients," 2020, Endocrine Related Cancer
  • "A Transcriptional Regulatory Loop of Master Regulator Transcription Factors, PPARG, and Fatty Acid Synthesis Promotes Esophageal Adenocarcinoma," 2021, Cancer Research
  • "Bone marrow mesenchymal stem cells interact with head and neck squamous cell carcinoma cells to promote cancer progression and drug resistance," 2020, Neoplasia
  • "Deconstructing tumor heterogeneity: the stromal perspective," 2020, Oncotarget

Collaboration is a significant component of their research, with frequent co-authors including:

  • Edwin M. Posadas
  • Sandrine Billet
  • Jun Gong
  • Lila M. Gierasch
  • F. Peter Guengerich

Best Publications

  • Stromal fibroblasts in cancer initiation and progression

    Neil A. Bhowmick;Eric G. Neilson;Harold L. Moses

  • TGF-ß Signaling in Fibroblasts Modulates the Oncogenic Potential of Adjacent Epithelia

    Neil A. Bhowmick;Anna Chytil;David Plieth;Agnieszka E. Gorska

  • Transforming Growth Factor-β1 Mediates Epithelial to Mesenchymal Transdifferentiation through a RhoA-dependent Mechanism

    Neil A. Bhowmick;Mayshan Ghiassi;Andrei Bakin;Mary Aakre

  • Phosphatidylinositol 3-Kinase Function Is Required for Transforming Growth Factor β-mediated Epithelial to Mesenchymal Transition and Cell Migration

    Andrei V. Bakin;Anne K. Tomlinson;Neil A. Bhowmick;Harold L. Moses

  • Tumor–stroma interactions

    Neil A Bhowmick;Harold L Moses

  • Role of EMT in Metastasis and Therapy Resistance

    Bethany N. Smith;Neil A. Bhowmick

  • Integrin β1 Signaling Is Necessary for Transforming Growth Factor-β Activation of p38MAPK and Epithelial Plasticity

    Neil A. Bhowmick;Roy Zent;Roy Zent;Mayshan Ghiassi;Maureen McDonnell

  • Large Oncosomes in Human Prostate Cancer Tissues and in the Circulation of Mice with Metastatic Disease

    Dolores Di Vizio;Dolores Di Vizio;Dolores Di Vizio;Matteo Morello;Matteo Morello;Matteo Morello;Andrew C. Dudley;Peter W. Schow

  • Loss of TGF-β type II receptor in fibroblasts promotes mammary carcinoma growth and invasion through upregulation of TGF-α-, MSP- and HGF-mediated signaling networks

    Nikki Cheng;Neil A Bhowmick;Anna Chytil;Agnieszka E Gorksa

  • Essential Role of Smad3 in Angiotensin II–Induced Vascular Fibrosis

    Wansheng Wang;Xiao R. Huang;Ellery Canlas;Kazuhiro Oka

  • Large oncosomes mediate intercellular transfer of functional microRNA.

    Matteo Morello;Valentina R Minciacchi;Paola de Candia;Julie Yang

  • The Nuclear Factor-κB Pathway Controls the Progression of Prostate Cancer to Androgen-Independent Growth

    Ren Jie Jin;Yongsoo Lho;Linda Connelly;Yongqing Wang

  • Altered TGF-β Signaling in a Subpopulation of Human Stromal Cells Promotes Prostatic Carcinogenesis

    Omar E. Franco;Ming Jiang;Douglas W. Strand;James Peacock

  • Determination of residues important in hormone binding to the extracellular domain of the luteinizing hormone/chorionic gonadotropin receptor by site-directed mutagenesis and modeling.

    N Bhowmick;J Huang;D Puett;N W Isaacs

  • Prostate tumor progression is mediated by a paracrine TGF-β/Wnt3a signaling axis

    Xiaohong Li;Veronica Placencio;Juan M. Iturregui;Juan M. Iturregui;Consolate Uwamariya

  • Transforming growth factor beta-regulated gene expression in a mouse mammary gland epithelial cell line

    Lu Xie;Brian K. Law;Mary E. Aakre;Mary Elizabeth Edgerton

  • Transgenic Mice Expressing a Dominant-Negative Mutant Type II Transforming Growth Factor-β Receptor Exhibit Impaired Mammary Development and Enhanced Mammary Tumor Formation

    Agnieszka E. Gorska;Roy A. Jensen;Yu Shyr;Mary E. Aakre

  • The E3 Ubiquitin Ligase Siah2 Contributes to Castration-Resistant Prostate Cancer by Regulation of Androgen Receptor Transcriptional Activity

    Jianfei Qi;Manisha Tripathi;Rajeev Mishra;Natasha Sahgal

  • TGF-beta-induced RhoA and p160ROCK activation is involved in the inhibition of Cdc25A with resultant cell-cycle arrest.

    Neil A. Bhowmick;Mayshan Ghiassi;Mary Aakre;Kimberly Brown

  • MYC Mediates Large Oncosome-Induced Fibroblast Reprogramming in Prostate Cancer.

    Valentina R. Minciacchi;Cristiana Spinelli;Mariana Reis-Sobreiro;Lorenzo Cavallini;Lorenzo Cavallini

Frequent Co-Authors

Leland W.K. Chung
Leland W.K. Chung Cedars-Sinai Medical Center
Harold L. Moses
Harold L. Moses Vanderbilt University
Simon W. Hayward
Simon W. Hayward NorthShore University HealthSystem
Michael R. Freeman
Michael R. Freeman Cedars-Sinai Medical Center
Robert J. Matusik
Robert J. Matusik Vanderbilt University Medical Center
Stephen J. Freedland
Stephen J. Freedland Cedars-Sinai Medical Center
Dolores Di Vizio
Dolores Di Vizio Cedars-Sinai Medical Center
Jeffrey M. Karp
Jeffrey M. Karp Brigham and Women's Hospital
David Puett
David Puett University of Georgia
Maurizio Pellecchia
Maurizio Pellecchia University of California, Riverside

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