World's Best Scientists 2026 revealed!

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Biology and Biochemistry

D-Index
81
Citations
26524
World Ranking
3843
National Ranking
1903

Medicine

D-Index
80
Citations
26415
World Ranking
17017
National Ranking
8534

Overview

Michael M. Shen is affiliated with Columbia University in the United States. Their research primarily focuses on the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with substantial contributions in molecular biology, pulmonary and respiratory medicine, surgery, oncology, and cancer research.

Their work covers numerous topics, including:

  • Prostate Cancer Treatment and Research
  • Bladder and Urothelial Cancer Treatments
  • Immunotherapy and Immune Responses
  • Epigenetics and DNA Methylation
  • RNA Research and Splicing
  • Cancer Cells and Metastasis
  • Hepatitis C virus research

Michael M. Shen has frequently published in venues such as:

  • Cancer Research
  • bioRxiv (Cold Spring Harbor Laboratory)
  • SSRN Electronic Journal
  • Journal of Hepatology
  • The Journal of Urology

Their recent significant papers include:

  • "A single-cell atlas of the mouse and human prostate reveals heterogeneity and conservation of epithelial progenitors" (2020, eLife)
  • "B7-H3 as a Therapeutic Target in Advanced Prostate Cancer" (2022, European Urology)
  • "Green new hiring" (2022, Review of Accounting Studies)
  • "Functional redundancy of type I and type II receptors in the regulation of skeletal muscle growth by myostatin and activin A" (2020, Proceedings of the National Academy of Sciences)
  • "NKX3.1 Localization to Mitochondria Suppresses Prostate Cancer Initiation" (2021, Cancer Discovery)

The scientist frequently collaborates with other researchers, including:

  • John R. Christin
  • Andrea Califano
  • Cory Abate-Shen
  • Alessandro Vasciaveo
  • James M. McKiernan

Best Publications

  • Molecular genetics of prostate cancer: new prospects for old challenges

    Michael M. Shen;Cory Abate-Shen

  • Molecular genetics of prostate cancer

    Cory Abate-Shen;Michael M. Shen

  • Evidence for evolutionary conservation of sex-determining genes

    Christopher S. Raymond;Caroline E. Shamu;Caroline E. Shamu;Michael M. Shen;Michael M. Shen;Kelly J. Seifert

  • Murine FGFR-1 is required for early postimplantation growth and axial organization.

    C X Deng;A Wynshaw-Boris;M M Shen;C Daugherty

  • A luminal epithelial stem cell that is a cell of origin for prostate cancer

    Xi Wang;Marianna Kruithof-de Julio;Kyriakos D. Economides;Kyriakos D. Economides;Kyriakos D. Economides;David Walker;David Walker

  • Roles for Nkx3.1 in prostate development and cancer

    Rajula Bhatia-Gaur;Annemarie A. Donjacour;Peter J. Sciavolino;Peter J. Sciavolino;Minjung Kim;Minjung Kim

  • Tumor Evolution and Drug Response in Patient-Derived Organoid Models of Bladder Cancer

    Suk Hyung Lee;Wenhuo Hu;Justin T. Matulay;Mark V. Silva

  • Nodal signaling: developmental roles and regulation

    Michael M. Shen

  • Nodal signalling in vertebrate development

    Alexander F. Schier;Michael M. Shen

  • Cripto is required for correct orientation of the anterior–posterior axis in the mouse embryo

    Jixiang Ding;Lu Yang;Yu Ting Yan;Amy Chen

  • Long-term in vitro culture and characterisation of avian embryonic stem cells with multiple morphogenetic potentialities

    B. Pain;M.E. Clark;M. Shen;H. Nakazawa

  • Essential role for p38α mitogen-activated protein kinase in placental angiogenesis

    John S. Mudgett;Jixiang Ding;Lucia Guh-Siesel;Nicole A. Chartrain

  • Cooperativity of Nkx3.1 and Pten loss of function in a mouse model of prostate carcinogenesis

    Minjung J. Kim;Robert D. Cardiff;Nishita Desai;Nishita Desai;Whitney A. Banach-Petrosky;Whitney A. Banach-Petrosky

  • Genetic evidence for nonredundant functional cooperativity between NPC1 and NPC2 in lipid transport

    David E. Sleat;Jennifer A. Wiseman;Mukarram El-Banna;Sandy M. Price

  • Lineage analysis of basal epithelial cells reveals their unexpected plasticity and supports a cell-of-origin model for prostate cancer heterogeneity

    Zhu A. Wang;Antonina Mitrofanova;Sarah K. Bergren;Cory Abate-Shen

  • Inactivation of p53 and Pten promotes invasive bladder cancer

    Anna M. Puzio-Kuter;Mireia Castillo-Martin;Carolyn W. Kinkade;Xi Wang

  • Loss-of-function mutations in the EGF-CFC gene CFC1 are associated with human left-right laterality defects.

    Richard N. Bamford;Erich Roessler;Rebecca D. Burdine;Umay Şaplakoğlu

  • Monomethylation of histone H4-lysine 20 is involved in chromosome structure and stability and is essential for mouse development.

    Hisanobu Oda;Ikuhiro Okamoto;Niall Murphy;Jianhua Chu;Jianhua Chu

  • Heterodimerization of Msx and Dlx homeoproteins results in functional antagonism.

    H Zhang;G Hu;H Wang;P Sciavolino

  • Cross-species regulatory network analysis identifies a synergistic interaction between FOXM1 and CENPF that drives prostate cancer malignancy.

    Alvaro Aytes;Antonina Mitrofanova;Celine Lefebvre;Mariano J. Alvarez

Frequent Co-Authors

Cory Abate-Shen
Cory Abate-Shen Columbia University
Andrea Califano
Andrea Califano Columbia University
Robert D. Cardiff
Robert D. Cardiff University of California, Davis
Mark A. Rubin
Mark A. Rubin University of Bern
Hanina Hibshoosh
Hanina Hibshoosh Columbia University
Philip Leder
Philip Leder Harvard University
Massimo Loda
Massimo Loda Cornell University
Alexander F. Schier
Alexander F. Schier University of Basel
Robert J. Matusik
Robert J. Matusik Vanderbilt University Medical Center
Hiroshi Hamada
Hiroshi Hamada RIKEN Center for Biosystems Dynamics Research

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