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Mengqing Xiang

Mengqing Xiang

D-Index & Metrics

Neuroscience

D-Index
44
Citations
7718
World Ranking
7158
National Ranking
111

Overview

Mengqing Xiang is affiliated with Sun Yat-sen University in China. Their research focus spans multiple areas within biochemistry, genetics, molecular biology, and neuroscience. The scientist's work is concentrated in both main fields and subfields, including:

  • Biochemistry, Genetics and Molecular Biology
  • Neuroscience

  • Molecular Biology
  • Cellular and Molecular Neuroscience
  • Cancer Research
  • Immunology
  • Developmental Neuroscience

The core topics of their research include:

  • Retinal Development and Disorders
  • Pluripotent Stem Cells Research
  • RNA modifications and cancer
  • Cancer-related molecular mechanisms research
  • Neuroscience and Neural Engineering
  • Interferon and immune responses
  • Neurogenesis and neuroplasticity mechanisms

Mengqing Xiang has published research in a range of scientific journals, with frequent appearances in these venues:

  • International Journal of Molecular Sciences
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nucleic Acids Research
  • Frontiers in Cell and Developmental Biology
  • Proceedings of the National Academy of Sciences

Recent papers by Mengqing Xiang include:

  • Single-cell transcriptomics of adult macaque hippocampus reveals neural precursor cell populations (2022, Nature Neuroscience)
  • Deficiency of ribosomal proteins reshapes the transcriptional and translational landscape in human cells (2022, Nucleic Acids Research)
  • Generation of self-organized sensory ganglion organoids and retinal ganglion cells from fibroblasts (2020, Science Advances)
  • Foxn4 is a temporal identity factor conferring mid/late-early retinal competence and involved in retinal synaptogenesis (2020, Proceedings of the National Academy of Sciences)
  • In vivo Regeneration of Ganglion Cells for Vision Restoration in Mammalian Retinas (2021, Frontiers in Cell and Developmental Biology)

Throughout their career, Mengqing Xiang has worked with a set of frequent co-authors, including:

  • Shuting Liu
  • Dongchang Xiao
  • Kangxin Jin
  • Yanan Guo
  • Zhi Xie

Best Publications

  • The Brn-3 family of POU-domain factors: Primary structure, binding specificity, and expression in subsets of retinal ganglion cells and somatosensory neurons

    Mengqing Xiang;Lijuan Zhou;Jennifer P. Macke;Takashi Yoshioka

  • Essential role of POU–domain factor Brn-3c in auditory and vestibular hair cell development

    Mengqing Xiang;Lin Gan;Daqing Li;Zhi Yong Chen

  • POU domain factor Brn-3b is required for the development of a large set of retinal ganglion cells

    Lin Gan;Mengqing Xiang;Lijuan Zhou;Daniel S. Wagner

  • Requirement for Brn-3c in maturation and survival, but not in fate determination of inner ear hair cells

    Mengqing Xiang;Wei-Qiang Gao;Tama Hasson;Joyce J. Shin

  • Foxn4 controls the genesis of amacrine and horizontal cells by retinal progenitors

    Shengguo Li;Zeqian Mo;Xuejie Yang;Sandy M. Price

  • Brn-3b: a POU domain gene expressed in a subset of retinal ganglion cells.

    Mengqing Xiang;Lijuan Zhou;Y.-W. Peng;Roger L. Eddy

  • Ptf1a determines horizontal and amacrine cell fates during mouse retinal development

    Yoshio Fujitani;Shuko Fujitani;Shuko Fujitani;Huijun Luo;Feng Qiu

  • Targeted deletion of the mouse POU domain gene Brn-3a causes a selective loss of neurons in the brainstem and trigeminal ganglion, uncoordinated limb movement, and impaired suckling

    Mengqing Xiang;Lin Gan;Lijuan Zhou;William H. Klein

  • The Ath5 proneural genes function upstream of Brn3 POU domain transcription factor genes to promote retinal ganglion cell development

    Wei Liu;Zeqian Mo;Mengqing Xiang

  • All Brn3 genes can promote retinal ganglion cell differentiation in the chick.

    Wei Liu;Suvarna L. Khare;Xuelian Liang;Maureen A. Peters

  • Brn3a is a transcriptional regulator of soma size, target field innervation and axon pathfinding of inner ear sensory neurons.

    Eric J. Huang;Wei Liu;Wei Liu;Bernd Fritzsch;Bernd Fritzsch;Lynne M. Bianchi;Lynne M. Bianchi

  • Requirement for Brn-3b in early differentiation of postmitotic retinal ganglion cell precursors.

    Mengqing Xiang

  • POU domain factor Brn-3a controls the differentiation and survival of trigeminal neurons by regulating Trk receptor expression.

    Eric J. Huang;Keling Zang;Andrea Schmidt;Asta Saulys

  • A regulatory network involving Foxn4, Mash1 and delta-like 4/Notch1 generates V2a and V2b spinal interneurons from a common progenitor pool

    Marta G. Del Barrio;Raquel Taveira-Marques;Yuko Muroyama;Dong In Yuk

  • Barhl1 Regulates Migration and Survival of Cerebellar Granule Cells by Controlling Expression of the Neurotrophin-3 Gene

    Shengguo Li;Feng Qiu;Anlong Xu;Sandy M. Price

  • Intrinsic control of mammalian retinogenesis

    Mengqing Xiang

  • Brn3c null mutant mice show long-term, incomplete retention of some afferent inner ear innervation

    Mengqing Xiang;Adel Maklad;Ulla Pirvola;Bernd Fritzsch

  • Hearing loss caused by progressive degeneration of cochlear hair cells in mice deficient for the Barhl1 homeobox gene.

    Shengguo Li;Sandy M. Price;Hugh Cahill;David K. Ryugo

  • Role of the Barhl2 homeobox gene in the specification of glycinergic amacrine cells.

    Zeqian Mo;Shengguo Li;Xuejie Yang;Mengqing Xiang

  • A Comprehensive Negative Regulatory Program Controlled by Brn3b to Ensure Ganglion Cell Specification from Multipotential Retinal Precursors

    Feng Qiu;Haisong Jiang;Mengqing Xiang

  • Essential role of POU- domain factor Brn-3c in auditory and vestibular hair cell development (inner ear development)

    Mengqing Xiang;L In Gan;D Aqing Li;Z Hi-Yong Chen

Frequent Co-Authors

Bernd Fritzsch
Bernd Fritzsch University of Nebraska Medical Center
Frans P.M. Cremers
Frans P.M. Cremers Radboud University
Louis F. Reichardt
Louis F. Reichardt University of California, San Francisco
Anlong Xu
Anlong Xu Beijing University of Chinese Medicine
Jeffrey L. Goldberg
Jeffrey L. Goldberg Stanford University
Roger L. Eddy
Roger L. Eddy Roswell Park Cancer Institute
Hannie Kremer
Hannie Kremer Radboud University
Lies H. Hoefsloot
Lies H. Hoefsloot Erasmus University Rotterdam
Bin Tian
Bin Tian The Wistar Institute
Karen B. Avraham
Karen B. Avraham Tel Aviv University

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