Jacob E. Corn

Overview

Best Publications

• ROSETTA3: an object-oriented software suite for the simulation and design of macromolecules.

  Andrew Leaver-Fay;Michael Tyka;Steven M. Lewis;Oliver F. Lange

  2124
  Citations

• Enhancing homology-directed genome editing by catalytically active and inactive CRISPR-Cas9 using asymmetric donor DNA

  Christopher D Richardson;Graham J Ray;Mark A DeWitt;Gemma L Curie

  1250
  Citations

• A prudent path forward for genomic engineering and germline gene modification

  David Baltimore;Paul Berg;Michael Botchan;Dana Carroll

  954
  Citations

• Compact and highly active next-generation libraries for CRISPR-mediated gene repression and activation

  Max A. Horlbeck;Luke A. Gilbert;Jacqueline E. Villalta;Brittany Susan Adamson

  783
  Citations

• Nanoparticle delivery of Cas9 ribonucleoprotein and donor DNA in vivo induces homology-directed DNA repair

  Kunwoo Lee;Michael Conboy;Hyo Min Park;Fuguo Jiang

  745
  Citations

• Computational design of proteins targeting the conserved stem region of influenza hemagglutinin.

  Sarel J. Fleishman;Timothy A. Whitehead;Damian C. Ekiert;Cyrille Dreyfus

  689
  Citations

• RosettaScripts: A Scripting Language Interface to the Rosetta Macromolecular Modeling Suite

  Sarel J. Fleishman;Andrew Leaver-Fay;Jacob E. Corn;Eva Maria Strauch

  635
  Citations

• Enhancer connectome in primary human cells identifies target genes of disease-associated DNA elements

  Maxwell R Mumbach;Ansuman T Satpathy;Evan A Boyle;Chao Dai

  532
  Citations

• Selection-free genome editing of the sickle mutation in human adult hematopoietic stem/progenitor cells.

  Mark A. DeWitt;Wendy Magis;Nicolas L. Bray;Tianjiao Wang

  503
  Citations

• Cornerstones of CRISPR-Cas in drug discovery and therapy

  Christof Fellmann;Benjamin G. Gowen;Pei-Chun Lin;Pei-Chun Lin;Jennifer A. Doudna

  456
  Citations

• Unbiased detection of CRISPR off-targets in vivo using DISCOVER-Seq.

  Beeke Wienert;Beeke Wienert;Stacia K. Wyman;Christopher D. Richardson;Charles D. Yeh

  421
  Citations

• Advances in genome editing through control of DNA repair pathways.

  Charles D Yeh;Christopher D Richardson;Jacob E Corn

  399
  Citations

• Disabling Cas9 by an anti-CRISPR DNA mimic

  Jiyung Shin;Fuguo Jiang;Fuguo Jiang;Jun Jie Liu;Jun Jie Liu;Nicolas L. Bray

  341
  Citations

• USP30 and parkin homeostatically regulate atypical ubiquitin chains on mitochondria

  Christian N. Cunningham;Joshua M. Baughman;Lilian Phu;Joy S. Tea

  323
  Citations

• Discovery of stimulation-responsive immune enhancers with CRISPR activation

  Dimitre R. Simeonov;Benjamin G. Gowen;Mandy Boontanrart;Theodore L. Roth

  318
  Citations

• PnB Designer: a web application to design prime and base editor guide RNAs for animals and plants.

  Sebastian M. Siegner;Mehmet E. Karasu;Markus S. Schröder;Zacharias Kontarakis

  311
  Citations

• SLC19A1 transports immunoreactive cyclic dinucleotides.

  Rutger D. Luteijn;Shivam A. Zaver;Benjamin G. Gowen;Stacia K. Wyman

  290
  Citations

• A Genome-wide ER-phagy Screen Highlights Key Roles of Mitochondrial Metabolism and ER-Resident UFMylation.

  Jin Rui Liang;Jin Rui Liang;Emily Lingeman;Thao Luong;Saba Ahmed

  253
  Citations

• CRISPR–Cas9 genome editing in human cells occurs via the Fanconi anemia pathway

  Chris D. Richardson;Katelynn R. Kazane;Sharon J. Feng;Elena Zelin

  252
  Citations

• A De Novo Protein Binding Pair By Computational Design and Directed Evolution

  John Karanicolas;John Karanicolas;Jacob E. Corn;Irwin Chen;Lukasz A. Joachimiak

  190
  Citations