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Biology and Biochemistry

D-Index
54
Citations
19311
World Ranking
15363
National Ranking
283

Overview

Stefan Wieland is affiliated with the University Hospital of Basel in Switzerland. Their research spans multiple fields within medicine and molecular biology, with a strong focus on hepatology and infectious diseases related to the liver.

Their main fields of study include:

  • Medicine
  • Biochemistry, Genetics and Molecular Biology

Wieland's work covers several subfields, primarily:

  • Hepatology
  • Epidemiology
  • Molecular Biology
  • Cancer Research
  • Surgery

The main research topics that have been a focus throughout Wieland's career are:

  • Hepatitis B Virus Studies
  • Hepatitis C virus research
  • Hepatocellular Carcinoma Treatment and Prognosis
  • Liver Disease Diagnosis and Treatment
  • RNA modifications and cancer
  • Cancer, Lipids, and Metabolism
  • Cancer-related molecular mechanisms research

Stefan Wieland has authored multiple recent scientific papers published in recognized journals. Significant contributions include:

  • "Peroxisomal β-oxidation acts as a sensor for intracellular fatty acids and regulates lipolysis" (2021, Nature Metabolism)
  • "Integrative proteogenomic characterization of hepatocellular carcinoma across etiologies and stages" (2022, Nature Communications)
  • "Ubiquitous expression of HBsAg from integrated HBV DNA in patients with low viral load" (2021, Journal of Hepatology)
  • "Transition to HBeAg-negative chronic hepatitis B virus infection is associated with reduced cccDNA transcriptional activity" (2020, Journal of Hepatology)
  • "Interferon lambda 4 impairs hepatitis C viral antigen presentation and attenuates T cell responses" (2021, Nature Communications)

The venues where Wieland has frequently published include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Hepatology
  • Nature Communications
  • Clinical Pharmacology in Drug Development
  • Nature Metabolism

Stefan Wieland's collaborative network involves several frequent coauthors such as:

  • Markus H. Heim
  • Aleksei Suslov
  • Charlotte K.Y. Ng
  • Tuyana Boldanova
  • Marie-Anne Meier

Best Publications

  • Robust hepatitis C virus infection in vitro

    Jin Zhong;Pablo Gastaminza;Guofeng Cheng;Sharookh Kapadia

  • CD8+ T Cells Mediate Viral Clearance and Disease Pathogenesis during Acute Hepatitis B Virus Infection

    Robert Thimme;Stefan Wieland;Carola Steiger;John Ghrayeb

  • Interferon modulation of cellular microRNAs as an antiviral mechanism.

    Irene M. Pedersen;Guofeng Cheng;Stefan Wieland;Stefano Volinia

  • Genomic analysis of the host response to hepatitis C virus infection.

    Andrew I. Su;John P. Pezacki;Lisa Wodicka;Amy D. Brideau

  • Inhibition of hepatitis B virus in mice by RNA interference.

    Anton P McCaffrey;Hiroyuki Nakai;Kusum Pandey;Zan Huang

  • Viral and immunological determinants of hepatitis C virus clearance, persistence, and disease

    Robert Thimme;Jens Bukh;Hans Christian Spangenberg;Stefan Wieland

  • Stealth and cunning: hepatitis B and hepatitis C viruses.

    Stefan F. Wieland;Francis V. Chisari

  • Cellular Determinants of Hepatitis C Virus Assembly, Maturation, Degradation, and Secretion

    Pablo Gastaminza;Guofeng Cheng;Stefan Wieland;Jin Zhong

  • Pathogenesis of hepatitis B virus infection.

    Francis V. Chisari;Masanori Isogawa;Stefan F. Wieland

  • Short-range exosomal transfer of viral RNA from infected cells to plasmacytoid dendritic cells triggers innate immunity

    Marlène Dreux;Urtzi Garaigorta;Bryan Boyd;Elodie Décembre

  • The autophagy machinery is required to initiate hepatitis C virus replication

    Marlène Dreux;Pablo Gastaminza;Stefan F. Wieland;Francis V. Chisari

  • Human liver chimeric mice provide a model for hepatitis B and C virus infection and treatment

    Karl-Dimiter Bissig;Stefan F. Wieland;Phu Tran;Masanori Isogawa

  • The Size of the Viral Inoculum Contributes to the Outcome of Hepatitis B Virus Infection

    Shinichi Asabe;Stefan F. Wieland;Pratip K. Chattopadhyay;Mario Roederer

  • Organoid Models of Human Liver Cancers Derived from Tumor Needle Biopsies

    Sandro Nuciforo;Isabel Fofana;Matthias S. Matter;Tanja Blumer

  • Intrahepatic induction of alpha/beta interferon eliminates viral RNA-containing capsids in hepatitis B virus transgenic mice.

    Stefan F. Wieland;Luca G. Guidotti;Francis V. Chisari

  • Plasmacytoid dendritic cells sense hepatitis C virus–infected cells, produce interferon, and inhibit infection

    Ken Takahashi;Shinichi Asabe;Stefan Wieland;Urtzi Garaigorta

  • Immune effectors required for hepatitis B virus clearance

    Priscilla L. Yang;Alana Althage;Josan Chung;Holly Maier

  • Expansion and contraction of the hepatitis B virus transcriptional template in infected chimpanzees

    Stefan F. Wieland;Hans Christian Spangenberg;Robert Thimme;Robert H. Purcell

  • Blocking Chemokine Responsive to γ–2/Interferon (IFN)-γ Inducible Protein and Monokine Induced by IFN-γ Activity In Vivo Reduces the Pathogenetic but not the Antiviral Potential of Hepatitis B Virus–specific Cytotoxic T Lymphocytes

    Kazuhiro Kakimi;Thomas E. Lane;Stefan Wieland;Valerie C. Asensio

  • Interleukin-18 Inhibits Hepatitis B Virus Replication in the Livers of Transgenic Mice

    Kiminori Kimura;Kazuhiro Kakimi;Stefan Wieland;Luca G. Guidotti

Frequent Co-Authors

Francis V. Chisari
Francis V. Chisari Scripps Research Institute
Hubert E. Blum
Hubert E. Blum University of Freiburg
Robert H. Purcell
Robert H. Purcell National Institute of Allergy and Infectious Diseases
Luca G. Guidotti
Luca G. Guidotti Vita-Salute San Raffaele University
Darius Moradpour
Darius Moradpour University of Lausanne
Markus H. Heim
Markus H. Heim University Hospital of Basel
Robert Thimme
Robert Thimme University of Freiburg
Kazuhiro Kakimi
Kazuhiro Kakimi Kindai University
Philippe Gallay
Philippe Gallay Scripps Research Institute
Eric E. Swayze
Eric E. Swayze Ionis Pharmaceuticals (United States)

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