D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Genetics D-index 72 Citations 30,176 225 World Ranking 1388 National Ranking 656

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Cancer
  • DNA

His scientific interests lie mostly in DNA methylation, Genetics, CpG site, Methylation and Molecular biology. His DNA methylation study combines topics in areas such as Cancer research and Transcription factor. His Genetics study frequently draws connections between related disciplines such as Computational biology.

His CpG site research incorporates themes from Bisulfite sequencing and Epigenetics. His Methylation research is multidisciplinary, incorporating elements of Tumor suppressor gene and Epigenetics of physical exercise. His biological study spans a wide range of topics, including DNA methyltransferase, GA-Binding Protein Transcription Factor, Regulation of gene expression, Gene and O-6-methylguanine-DNA methyltransferase.

His most cited work include:

  • Integrative analysis of 111 reference human epigenomes (3776 citations)
  • The clonal and mutational evolution spectrum of primary triple-negative breast cancers (1368 citations)
  • The NIH Roadmap Epigenomics Mapping Consortium (1307 citations)

What are the main themes of his work throughout his whole career to date?

His primary areas of investigation include Cancer research, DNA methylation, Genetics, Epigenetics and Glioma. His research in Cancer research intersects with topics in Immunology, Cancer and Gene, Mutant. The various areas that Joseph F. Costello examines in his DNA methylation study include Carcinogenesis, Molecular biology and Methylation.

The Methylation study combines topics in areas such as Gene expression and Epigenetics of physical exercise. His work on Genetics deals in particular with Illumina Methylation Assay, Human genome, Differentially methylated regions, Restriction landmark genomic scanning and RNA-Directed DNA Methylation. His work in Epigenomics tackles topics such as Computational biology which are related to areas like Genome.

He most often published in these fields:

  • Cancer research (33.74%)
  • DNA methylation (33.33%)
  • Genetics (24.80%)

What were the highlights of his more recent work (between 2018-2021)?

  • Cancer research (33.74%)
  • Glioma (18.70%)
  • Mutant (8.54%)

In recent papers he was focusing on the following fields of study:

Joseph F. Costello mainly focuses on Cancer research, Glioma, Mutant, DNA methylation and Somatic hypermutation. The study incorporates disciplines such as Telomere, Methylation and Telomerase reverse transcriptase in addition to Cancer research. His Glioma research is multidisciplinary, relying on both Gene, IDH1 and T-cell receptor.

Joseph F. Costello is interested in Epigenomics, which is a field of DNA methylation. He combines subjects such as Genome-wide association study, Computational biology and Neuroscience with his study of Epigenomics. His Carcinogenesis study integrates concerns from other disciplines, such as Bisulfite sequencing, Regulation of gene expression and Meningioma.

Between 2018 and 2021, his most popular works were:

  • Longitudinal molecular trajectories of diffuse glioma in adults (92 citations)
  • Saturation mutagenesis of twenty disease-associated regulatory elements at single base-pair resolution. (50 citations)
  • The DNA methylation landscape of advanced prostate cancer (26 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Cancer
  • DNA

His primary areas of study are Cancer research, Temozolomide, Somatic hypermutation, DNA methylation and Carcinogenesis. His research on Cancer research frequently connects to adjacent areas such as Methylation. His Methylation research integrates issues from Bisulfite sequencing, Regulation of gene expression, Deep sequencing and Somatic evolution in cancer.

His study in DNA methylation is interdisciplinary in nature, drawing from both Andrology and Transcriptome. His study in Epigenomics extends to Carcinogenesis with its themes. His study looks at the relationship between Epigenomics and fields such as Exome sequencing, as well as how they intersect with chemical problems.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Integrative analysis of 111 reference human epigenomes

Anshul Kundaje;Wouter Meuleman;Wouter Meuleman;Jason Ernst.
Nature (2015)

4957 Citations

The clonal and mutational evolution spectrum of primary triple-negative breast cancers

Sohrab P. Shah;Andrew Roth;Rodrigo Goya;Arusha Oloumi.
Nature (2012)

2010 Citations

Conserved role of intragenic DNA methylation in regulating alternative promoters

Alika K. Maunakea;Raman P. Nagarajan;Mikhail Bilenky;Tracy J. Ballinger.
Nature (2010)

1749 Citations

Aberrant CpG-island methylation has non-random and tumour-type-specific patterns.

Joseph F. Costello;Joseph F. Costello;Michael C. Frühwald;Michael C. Frühwald;Dominic J. Smiraglia;Laura J. Rush.
Nature Genetics (2000)

1730 Citations

The NIH Roadmap Epigenomics Mapping Consortium

Bradley E Bernstein;John A Stamatoyannopoulos;Joseph F Costello;Bing Ren.
Nature Biotechnology (2010)

1620 Citations

Mutational Analysis Reveals the Origin and Therapy-Driven Evolution of Recurrent Glioma

Brett E. Johnson;Tali Mazor;Chibo Hong;Michael Barnes.
Science (2014)

1210 Citations

miR-124 and miR-137 inhibit proliferation of glioblastoma multiforme cells and induce differentiation of brain tumor stem cells.

Joachim Silber;Daniel A Lim;Claudia Petritsch;Anders I Persson.
BMC Medicine (2008)

1087 Citations

The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.

John G McDonnell;Gerard Curley;John Carney;Aoife Benton.
Anesthesia & Analgesia (2008)

796 Citations

Comparison of sequencing-based methods to profile DNA methylation and identification of monoallelic epigenetic modifications

R Alan Harris;Ting Wang;Cristian Coarfa;Raman P. Nagarajan.
Nature Biotechnology (2010)

692 Citations

A hierarchy of self-renewing tumor-initiating cell types in glioblastoma

Ruihuan Chen;Merry C. Nishimura;Stephanie M. Bumbaca;Samir Kharbanda.
Cancer Cell (2010)

631 Citations

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