Patrick Descombes

Overview

Best Publications

• Genetic Variation in IL28B Is Associated With Chronic Hepatitis C and Treatment Failure: A Genome-Wide Association Study

  Andri Rauch;Zoltán Kutalik;Zoltán Kutalik;Patrick Descombes;Tao Cai

  1520
  Citations

• A Whole-Genome Association Study of Major Determinants for Host Control of HIV-1

  Jacques Fellay;Kevin V. Shianna;Dongliang Ge;Sara Colombo

  1514
  Citations

• A liver-enriched transcriptional activator protein, LAP, and a transcriptional inhibitory protein, LIP, are translated from the same mRNA.

  Patrick Descombes;Ulrich Schibler

  1514
  Citations

• Genome-wide gene-based analyses of weight loss interventions identify a potential role for NKX6.3 in metabolism.

  Armand Valsesia;Qiao-Ping Wang;Qiao-Ping Wang;Nele Gheldof;Jerome Carayol

  1088
  Citations

• LAP, a novel member of the C/EBP gene family, encodes a liver-enriched transcriptional activator protein.

  Patrick Descombes;Mario Chojkier;Serge Patrick Lichtsteiner;Eileen Elisabeth Falvey

  819
  Citations

• The circadian PAR-domain basic leucine zipper transcription factors DBP, TEF, and HLF modulate basal and inducible xenobiotic detoxification

  Frédéric Gachon;Fabienne Fleury Olela;Olivier Schaad;Patrick Descombes

  569
  Citations

• CCAAT/enhancer-binding protein mRNA is translated into multiple proteins with different transcription activation potentials.

  Vincent Ossipow;Patrick Descombes;Ulrich Schibler

  512
  Citations

• Common genetic variation and the control of HIV-1 in humans.

  Jacques Fellay;Dongliang Ge;Kevin V. Shianna;Sara Colombo

  475
  Citations

• Decoding NMDA Receptor Signaling: Identification of Genomic Programs Specifying Neuronal Survival and Death

  Sheng Jia Zhang;Marvin N. Steijaert;David Lau;Günther Schütz

  432
  Citations

• Comparative transcriptomics of rice reveals an ancient pattern of response to microbial colonization

  Sonia Güimil;Hur-Song Chang;Tong Zhu;Ane Sesma

  428
  Citations

• Nuclear calcium signaling controls expression of a large gene pool: identification of a gene program for acquired neuroprotection induced by synaptic activity.

  Sheng-Jia Zhang;Ming Zou;Li Lu;David Lau

  364
  Citations

• RefGenes: identification of reliable and condition specific reference genes for RT-qPCR data normalization

  Tomas Hruz;Markus Wyss;Mylene Docquier;Michael W Pfaffl

  332
  Citations

• Decreased epigenetic age of PBMCs from Italian semi-supercentenarians and their offspring.

  Steve Horvath;Chiara Pirazzini;Maria Giulia Bacalini;Davide Gentilini

  326
  Citations

• Gene expression during sex determination reveals a robust female genetic program at the onset of ovarian development

  Serge Nef;Olivier Schaad;Nancy R. Stallings;Christopher R. Cederroth

  303
  Citations

• The polo‐like kinase Plx1 is required for M phase exit and destruction of mitotic regulators in Xenopus egg extracts

  Patrick Descombes;Erich A. Nigg

  281
  Citations

• Loss of fibronectin from the aged stem cell niche affects the regenerative capacity of skeletal muscle in mice.

  Laura Lukjanenko;M Juliane Jung;Nagabhooshan Hegde;Claire Perruisseau-Carrier

  266
  Citations

• Natural Gene-Expression Variation in Down Syndrome Modulates the Outcome of Gene-Dosage Imbalance

  Paola Prandini;Samuel Deutsch;Robert Lyle;Maryline Gagnebin

  254
  Citations

• Aging Disrupts Muscle Stem Cell Function by Impairing Matricellular WISP1 Secretion from Fibro-Adipogenic Progenitors.

  Laura Lukjanenko;Laura Lukjanenko;Sonia Karaz;Pascal Stuelsatz;Uxia Gurriaran-Rodriguez;Uxia Gurriaran-Rodriguez

  253
  Citations

• Circadian and feeding rhythms differentially affect rhythmic mRNA transcription and translation in mouse liver

  Florian Atger;Cédric Gobet;Julien Marquis;Eva Martin

  235
  Citations

• Common Genetic Variation and the Control of HIV-1 in Humans

  Jacques Fellay;Dongliang Ge;Kevin V. Shianna;Sara Colombo

  23
  Citations