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Biology and Biochemistry

D-Index
61
Citations
21244
World Ranking
11121
National Ranking
798

Research.com Recognitions

  • 2019 - German National Academy of Sciences Leopoldina - Deutsche Akademie der Naturforscher Leopoldina – Nationale Akademie der Wissenschaften Neurosciences

Overview

Hilmar Bading is affiliated with Heidelberg University in Germany and has a research focus primarily within the fields of Neuroscience, Medicine, and Biochemistry, Genetics and Molecular Biology. Their scholarly output includes significant contributions to Molecular Biology, Cellular and Molecular Neuroscience, and Neurology, with further involvement in Physiology and Pharmacology.

The scientist's research spans key topics such as Neuroscience and Neuropharmacology Research, Alzheimer's disease research and treatments, Neuroinflammation and Neurodegeneration Mechanisms, Cholinesterase and Neurodegenerative Diseases, Mitochondrial Function and Pathology, Ion channel regulation and function, as well as Medicinal Plants and Neuroprotection.

Recent papers authored or co-authored by Hilmar Bading include:

  • Coupling of NMDA receptors and TRPM4 guides discovery of unconventional neuroprotectants (2020, Science)
  • The role of nuclear Ca2+ in maintaining neuronal homeostasis and brain health (2021, Journal of Cell Science)
  • Npas4 regulates medium spiny neuron physiology and gates cocaine-induced hyperlocomotion (2021, EMBO Reports)
  • Pathophysiological Ionotropic Glutamate Signalling in Neuroinflammatory Disease as a Therapeutic Target (2021, Frontiers in Neuroscience)
  • Neuron-astrocyte metabolic coupling facilitates spinal plasticity and maintenance of inflammatory pain (2024, Nature Metabolism)

Frequent co-authors with whom Hilmar Bading has collaborated include:

  • Anna M. Hagenston
  • Jing Yan
  • C. Peter Bengtson
  • Priit Pruunsild
  • Omar A. Ramírez

The scientist has published regularly in several venues, notably:

  • Journal of Biological Chemistry
  • Neuroscience
  • Molecular Brain
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Science

Hilmar Bading's work has been recognized by the German National Academy of Sciences Leopoldina in 2019 within the Neurosciences category.

Best Publications

  • Extrasynaptic NMDARs oppose synaptic NMDARs by triggering CREB shut-off and cell death pathways

    Giles E. Hardingham;Yuko Fukunaga;Hilmar Bading;Hilmar Bading

  • Synaptic versus extrasynaptic NMDA receptor signalling: implications for neurodegenerative disorders

    Giles E. Hardingham;Hilmar Bading

  • Regulation of gene expression in hippocampal neurons by distinct calcium signaling pathways

    Hilmar Bading;David D. Ginty;Michael E. Greenberg

  • Regulation of CREB phosphorylation in the suprachiasmatic nucleus by light and a circadian clock

    David D. Ginty;Jon M. Kornhauser;Margaret A. Thompson;Hilmar Bading;Hilmar Bading

  • Distinct functions of nuclear and cytoplasmic calcium in the control of gene expression

    Giles E. Hardingham;Sangeeta Chawla;Claire M. Johnson;Hilmar Bading

  • The Yin and Yang of NMDA receptor signalling.

    Giles E. Hardingham;Hilmar Bading

  • Stimulation of protein tyrosine phosphorylation by NMDA receptor activation

    Hilmar Bading;Michael E. Greenberg

  • Nuclear calcium signaling controls CREB-mediated gene expression triggered by synaptic activity.

    Giles E. Hardingham;Fiona J. L. Arnold;Hilmar Bading

  • CBP: A Signal-Regulated Transcriptional Coactivator Controlled by Nuclear Calcium and CaM Kinase IV

    Sangeeta Chawla;Giles E. Hardingham;David R. Quinn;Hilmar Bading

  • Nuclear calcium signalling in the regulation of brain function

    Hilmar Bading

  • Decoding NMDA Receptor Signaling: Identification of Genomic Programs Specifying Neuronal Survival and Death

    Sheng Jia Zhang;Marvin N. Steijaert;David Lau;Günther Schütz

  • Calcium regulation of gene expression in neuronal cells.

    Anirvan Ghosh;David D. Ginty;Hilmar Bading;Michael E. Greenberg

  • A calcium microdomain near NMDA receptors: on switch for ERK-dependent synapse-to-nucleus communication

    Giles E. Hardingham;Fiona J. L. Arnold;Hilmar Bading

  • Nuclear calcium signaling controls expression of a large gene pool: identification of a gene program for acquired neuroprotection induced by synaptic activity.

    Sheng-Jia Zhang;Ming Zou;Li Lu;David Lau

  • Control of Recruitment and Transcription-Activating Function of CBP Determines Gene Regulation by NMDA Receptors and L-Type Calcium Channels

    Giles E. Hardingham;Sangeeta Chawla;Francisco H. Cruzalegui;Hilmar Bading

  • Neuronal activity-dependent nucleocytoplasmic shuttling of HDAC4 and HDAC5.

    Sangeeta Chawla;Peter Vanhoutte;Peter Vanhoutte;Fiona J. L. Arnold;Christopher L.-H. Huang

  • Nuclear Ca2+ and the cAMP Response Element-Binding Protein Family Mediate a Late Phase of Activity-Dependent Neuroprotection

    Sofia Papadia;Patrick Stevenson;Neil R. Hardingham;Hilmar Bading

  • Opposing roles of synaptic and extrasynaptic NMDA receptors in neuronal calcium signalling and BDNF gene regulation

    Peter Vanhoutte;Hilmar Bading

  • Rescue of aging-associated decline in Dnmt3a2 expression restores cognitive abilities

    Ana M M Oliveira;Thekla J Hemstedt;Hilmar Bading

  • Preconditioning Doses of NMDA Promote Neuroprotection by Enhancing Neuronal Excitability

    Francesc X. Soriano;Sofia Papadia;Frank Hofmann;Neil R. Hardingham

Frequent Co-Authors

Giles E. Hardingham
Giles E. Hardingham University of Edinburgh
Michael E. Greenberg
Michael E. Greenberg Harvard University
Joachim P. Spatz
Joachim P. Spatz Max Planck Society
Rainer Spanagel
Rainer Spanagel Heidelberg University
David D. Ginty
David D. Ginty Howard Hughes Medical Institute
Valery Grinevich
Valery Grinevich Heidelberg University
Rohini Kuner
Rohini Kuner Heidelberg University
Andreas Draguhn
Andreas Draguhn Heidelberg University
David J. A. Wyllie
David J. A. Wyllie University of Edinburgh
Matthias Klugmann
Matthias Klugmann University of New South Wales

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