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D-Index
49
Citations
12263
World Ranking
5896
National Ranking
167

Overview

Matthias Klugmann is affiliated with the University of New South Wales in Australia. Their research primarily lies within the field of Biochemistry, Genetics and Molecular Biology, with a focus on Molecular Biology, Genetics, Biochemistry, Cellular and Molecular Neuroscience, and Clinical Biochemistry. This research spans a total of 45 publications in these areas.

Their recent work includes studies published between 2020 and 2022, contributing to various aspects of molecular neuroscience and therapeutic developments. Notable papers authored by Matthias Klugmann include:

  • L-Aspartate, L-Ornithine and L-Ornithine-L-Aspartate (LOLA) and Their Impact on Brain Energy Metabolism (2020, Neurochemical Research)
  • AAV9-mediated gene delivery of MCT1 to oligodendrocytes does not provide a therapeutic benefit in a mouse model of ALS (2021, Molecular Therapy - Methods & Clinical Development)
  • The Leukodystrophies HBSL and LBSL-Correlates and Distinctions (2021, Frontiers in Cellular Neuroscience)
  • Minimal Essential Human Factor VIII Alterations Enhance Secretion and Gene Therapy Efficiency (2020, Molecular Therapy - Methods & Clinical Development)
  • Dual-function AAV gene therapy reverses late-stage Canavan disease pathology in mice (2022, Frontiers in Molecular Neuroscience)

These publications reflect a consistent engagement with topics such as gene therapy, molecular alterations relevant to therapeutic applications, and neurological metabolic processes.

Matthias Klugmann has collaborated frequently with several researchers, including:

  • Gary D. Housley
  • Dominik Fröhlich
  • Georg von Jonquières
  • Jeremy L. Pinyon
  • Elizabeth Kalotay

Their studies have appeared in a range of scientific journals with multiple contributions to:

  • Neurochemical Research
  • Advanced Science
  • Molecular Therapy - Methods & Clinical Development
  • Frontiers in Cellular Neuroscience
  • Frontiers in Neuroscience

Within their wider research interests, Matthias Klugmann has addressed themes including:

  • RNA and protein synthesis mechanisms
  • RNA Research and Splicing
  • Virus-based gene therapy research
  • RNA modifications and cancer
  • RNA Interference and Gene Delivery
  • RNA regulation and disease
  • Advanced biosensing and bioanalysis techniques

This profile reflects the interdisciplinary nature of research combining molecular biology, genetics, and neuroscience, emphasizing the molecular underpinnings of disease processes and therapeutic strategies involving RNA and gene delivery technologies.

Best Publications

  • Axonal swellings and degeneration in mice lacking the major proteolipid of myelin

    Ian Griffiths;Matthias Klugmann;Matthias Klugmann;Matthias Klugmann;Thomas Anderson;Thomas Anderson;Thomas Anderson;Donald Yool;Donald Yool;Donald Yool

  • Glucagon-like peptide-1 receptor is involved in learning and neuroprotection

    Matthew J During;Lei Cao;David S Zuzga;Jeremy S Francis

  • Neurotransmitter-Triggered Transfer of Exosomes Mediates Oligodendrocyte–Neuron Communication

    Carsten Frühbeis;Dominik Fröhlich;Wen Ping Kuo;Jesa Amphornrat

  • The endocannabinoid system controls key epileptogenic circuits in the hippocampus.

    Krisztina Monory;Federico Massa;Federico Massa;Michaela Egertová;Matthias Eder

  • Mitochondrial CB1 receptors regulate neuronal energy metabolism

    Giovanni Bénard;Federico Massa;Federico Massa;Nagore Puente;Joana Lourenço

  • Assembly of CNS Myelin in the Absence of Proteolipid Protein

    Matthias Klugmann;Markus H. Schwab;Anja Pühlhofer;Armin Schneider

  • Patients lacking the major CNS myelin protein, proteolipid protein 1, develop length-dependent axonal degeneration in the absence of demyelination and inflammation.

    James Y. Garbern;Donald A. Yool;Gregory J. Moore;Ian B. Wilds

  • Synaptic Inhibition in the Olfactory Bulb Accelerates Odor Discrimination in Mice

    Nixon M. Abraham;Veronica Egger;Derya R. Shimshek;Robert Renden

  • Homer Proteins Regulate Sensitivity to Cocaine

    Karen K. Szumlinski;Marlin H. Dehoff;Shin H. Kang;Kelly A. Frys

  • AAV-mediated hippocampal expression of short and long Homer 1 proteins differentially affect cognition and seizure activity in adult rats.

    Matthias Klugmann;C. Wymond Symes;Claudia B. Leichtlein;Bettina K. Klaussner

  • Extinction Training after Cocaine Self-Administration Induces Glutamatergic Plasticity to Inhibit Cocaine Seeking

    Lori A. Knackstedt;Khaled Moussawi;Ryan Lalumiere;Marek Schwendt

  • AAV Vector–mediated RNAi of Mutant Huntingtin Expression Is Neuroprotective in a Novel Genetic Rat Model of Huntington's Disease

    Nicholas R Franich;Helen L Fitzsimons;Dahna M Fong;Matthias Klugmann

  • Tau exacerbates excitotoxic brain damage in an animal model of stroke

    Mian Bi;Amadeus Gladbach;Janet van Eersel;Arne Ittner

  • Binge drinking upregulates accumbens mGluR5-Homer2-PI3K signaling: functional implications for alcoholism.

    Debra K. Cozzoli;Scott P. Goulding;Ping Wu Zhang;Bo Xiao

  • Close-Field Electroporation Gene Delivery Using the Cochlear Implant Electrode Array Enhances the Bionic Ear

    Jeremy L. Pinyon;Sherif F. Tadros;Kristina E. Froud;Ann C. Y. Wong

  • Current concepts of PLP and its role in the nervous system.

    I Griffiths;M Klugmann;T Anderson;C Thomson

  • Synaptic scaffolding protein Homer1a protects against chronic inflammatory pain

    Anke Tappe;Matthias Klugmann;Ceng Luo;David Hirlinger

  • Late‐onset neurodegeneration in mice with increased dosage of the proteolipid protein gene

    T.J. Anderson;A. Schneider;J.A. Barrie;M. Klugmann

  • Nucleus accumbens mGluR5-associated signaling regulates binge alcohol drinking under drinking-in-the-dark procedures.

    Debra K. Cozzoli;Justin Courson;Amanda L. Caruana;Bailey W. Miller

  • Neuronal Basic Helix-Loop-Helix Proteins (NEX, neuroD, NDRF): Spatiotemporal Expression and Targeted Disruption of the NEX Gene in Transgenic Mice

    Markus H. Schwab;Silke Druffel-Augustin;Peter Gass;Martin Jung

  • Glial promoter selectivity following AAV-delivery to the immature brain.

    Georg von Jonquieres;Nadine Mersmann;Claudia Bettina Klugmann;Anne Editha Harasta

Frequent Co-Authors

Gary D. Housley
Gary D. Housley University of New South Wales
Klaus-Armin Nave
Klaus-Armin Nave Max Planck Society
Karen K. Szumlinski
Karen K. Szumlinski University of California, Santa Barbara
Paul F. Worley
Paul F. Worley Johns Hopkins University School of Medicine
Caroline Rae
Caroline Rae Neuroscience Research Australia
Beat Lutz
Beat Lutz Johannes Gutenberg University of Mainz
Peter W. Kalivas
Peter W. Kalivas Medical University of South Carolina
Giovanni Marsicano
Giovanni Marsicano University of Bordeaux
Sandra Goebbels
Sandra Goebbels Max Planck Society
Frank Kirchhoff
Frank Kirchhoff University of Ulm

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