World's Best Scientists 2026 revealed!

D-Index & Metrics

Neuroscience

D-Index
88
Citations
31365
World Ranking
1195
National Ranking
41

Medicine

D-Index
88
Citations
31366
World Ranking
13067
National Ranking
495

Overview

Roberto Spreafico is affiliated with the Istituto Neurologico Carlo Besta in Italy. Their research focuses primarily on epilepsy and related neurological conditions, with involvement in advanced imaging techniques, neurobiology, and neuropathology. Spreafico's work spans multiple interconnected fields within medicine and neuroscience.

Their main fields of study include:

  • Medicine
  • Neuroscience

More specific subfields of their research encompass:

  • Psychiatry and Mental Health
  • Radiology, Nuclear Medicine and Imaging
  • Cellular and Molecular Neuroscience
  • Cognitive Neuroscience
  • Molecular Biology

Their research topics cover a range of areas, with particular emphasis on:

  • Epilepsy Research and Treatment
  • Neuroscience and Neuropharmacology Research
  • Advanced MRI Techniques and Applications
  • Mitochondrial Function and Pathology
  • Functional Brain Connectivity Studies
  • Glioma Diagnosis and Treatment
  • Neuroinflammation and Neurodegeneration Mechanisms

Notable recent publications from Roberto Spreafico include:

  • Dendritic pathology, spine loss and synaptic reorganization in human cortex from epilepsy patients (2020, Brain)
  • Identifying the epileptogenic zone by four non-invasive imaging techniques versus stereo-EEG in MRI-negative pre-surgery epilepsy patients (2020, Clinical Neurophysiology)
  • Dendritic spine loss in epileptogenic Type II focal cortical dysplasia: Role of enhanced classical complement pathway activation (2022, Brain Pathology)
  • Why are type II focal cortical dysplasias frequently located at the bottom of sulcus? A neurodevelopmental hypothesis (2022, Epilepsia)
  • Drebrin expression patterns in patients with refractory temporal lobe epilepsy and hippocampal sclerosis (2020, Epilepsia)

Spreafico has contributed to journals with repeated presence in:

  • Epilepsia
  • Clinical Neurophysiology
  • Brain
  • Brain Pathology
  • Journal of Neuroscience Methods

The researcher has collaborated frequently with a core group of co-authors, including:

  • Laura Tassi
  • Rita Garbelli
  • L Rossini
  • Dalia De Santis
  • Marco de Curtis

Best Publications

  • Cross-neutralization of SARS-CoV-2 by a human monoclonal SARS-CoV antibody.

    Dora Pinto;Young Jun Park;Martina Beltramello;Alexandra C. Walls

  • The clinicopathologic spectrum of focal cortical dysplasias: A consensus classification proposed by an ad hoc Task Force of the ILAE Diagnostic Methods Commission

    Ingmar Blümcke;Maria Thom;Eleonora Aronica;Dawna D. Armstrong

  • Terminology and classification of the cortical dysplasias.

    André Palmini;Imad Najm;G. Avanzini;T. Babb

  • International consensus classification of hippocampal sclerosis in temporal lobe epilepsy: A Task Force report from the ILAE Commission on Diagnostic Methods

    Ingmar Blümcke;Maria Thom;Eleonora Aronica;Dawna D. Armstrong

  • Histopathological Findings in Brain Tissue Obtained during Epilepsy Surgery.

    Blumcke I;Spreafico R;Haaker G;Coras R

  • Focal cortical dysplasia: neuropathological subtypes, EEG, neuroimaging and surgical outcome.

    L. Tassi;N. Colombo;R. Garbelli;S. Francione

  • Pathogenesis, diagnosis and treatment of Rasmussen encephalitis A European consensus statement

    C. G. Bien;T. Granata;C. Antozzi;J. H. Cross

  • Circulating SARS-CoV-2 spike N439K variants maintain fitness while evading antibody-mediated immunity.

    Emma C. Thomson;Emma C. Thomson;Laura E. Rosen;James G. Shepherd;Roberto Spreafico

  • Perineuronal nets: past and present

    Marco R Celio;Roberto Spreafico;Silvia De Biasi;Laura Vitellaro-Zuccarello

  • Ultrapotent human antibodies protect against SARS-CoV-2 challenge via multiple mechanisms

    M. Alejandra Tortorici;M. Alejandra Tortorici;Martina Beltramello;Florian A. Lempp;Dora Pinto

  • A perspective on potential antibody-dependent enhancement of SARS-CoV-2.

    Ann M. Arvin;Katja Fink;Michael A. Schmid;Andrea Cathcart

  • From Big Data to Precision Medicine.

    Tim Hulsen;Saumya Shekhar Jamuar;Alan R. Moody;Jason H. Karnes

  • Type III interferons disrupt the lung epithelial barrier upon viral recognition.

    Achille Broggi;Sreya Ghosh;Benedetta Sposito;Benedetta Sposito;Roberto Spreafico

  • GABAergic neurons in mammalian thalamus: a marker of thalamic complexity?

    P Arcelli;C Frassoni;M.C Regondi;S.De Biasi

  • Seizure outcome and use of antiepileptic drugs after epilepsy surgery according to histopathological diagnosis: a retrospective multicentre cohort study

    Herm J Lamberink;Willem M Otte;Ingmar Blümcke;Kees P J Braun

  • GABAergic neurons are present in the dorsal column nuclei but not in the ventroposterior complex of rats

    P. Barbaresi;R. Spreafico;C. Frassoni;A. Rustioni

  • Exhaustion-associated regulatory regions in CD8+ tumor-infiltrating T cells.

    Giuliana P. Mognol;Roberto Spreafico;Victor Wong;James P. Scott-Browne

  • Focal cortical dysplasias: MR imaging, histopathologic, and clinical correlations in surgically treated patients with epilepsy.

    Nadia Colombo;Laura Tassi;Carlo Galli;Alberto Citterio

  • Intrinsic properties of nucleus reticularis thalami neurones of the rat studied in vitro.

    G Avanzini;M de Curtis;F Panzica;R Spreafico

  • Cortical dysplasia An immunocytochemical study of three patients

    R. Spreafico;G. Battaglia;P. Arcelli;F. Andermann

  • The interferon landscape along the respiratory tract impacts the severity of COVID-19.

    Benedetta Sposito;Achille Broggi;Laura Pandolfi;Stefania Crotta

  • Electroclinical, MRI and neuropathological study of 10 patients with nodular heterotopia, with surgical outcomes

    L. Tassi;N. Colombo;M. Cossu;R. Mai

  • In situ labeling of apoptotic cell death in the cerebral cortex and thalamus of rats during development

    R. Spreafico;C. Frassoni;P. Arcelli;M. Selvaggio

Frequent Co-Authors

Laura Tassi
Laura Tassi University of Bologna
Carolina Frassoni
Carolina Frassoni Istituto Neurologico Carlo Besta
Rita Garbelli
Rita Garbelli Istituto Neurologico Carlo Besta
Giuliano Avanzini
Giuliano Avanzini Istituto Neurologico Carlo Besta
Flavio Villani
Flavio Villani Istituto Neurologico Carlo Besta
Tiziana Granata
Tiziana Granata Istituto Neurologico Carlo Besta
Silvana Franceschetti
Silvana Franceschetti Istituto Neurologico Carlo Besta
Roberto Mai
Roberto Mai University of Milan
Giorgio Lo Russo
Giorgio Lo Russo Ospedale Niguarda Ca' Granda
Renato Mantegazza
Renato Mantegazza Istituto Neurologico Carlo Besta

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