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Neuroscience

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Overview

Imad Najm is affiliated with the Cleveland Clinic in the United States and has an extensive research portfolio concentrated primarily in medicine, neuroscience, and biochemistry, genetics, and molecular biology. Their work intersects several subfields including psychiatry and mental health, pediatrics, perinatology and child health, cellular and molecular neuroscience, genetics, and cognitive neuroscience.

The main topics of Imad Najm's research encompass epilepsy research and treatment, neuroscience and neuropharmacology research, pharmacological effects and toxicity studies, genomics and rare diseases, genetics and neurodevelopmental disorders, advanced MRI techniques and applications, as well as fetal and pediatric neurological disorders.

Najm has published in multiple recognized scientific venues, with frequent contributions to:

  • Epilepsia
  • Neurology
  • Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition
  • Brain Communications
  • Epilepsy & Behavior

Recent papers authored or coauthored by Najm provide insights into focal cortical dysplasia and epilepsy surgery techniques, including:

  • The ILAE consensus classification of focal cortical dysplasia: An update proposed by an ad hoc task force of the ILAE diagnostic methods commission, 2022, Epilepsia
  • Comparative Effectiveness of Stereotactic Electroencephalography Versus Subdural Grids in Epilepsy Surgery, 2021, Annals of Neurology
  • Value of 7T MRI and post-processing in patients with nonlesional 3T MRI undergoing epilepsy presurgical evaluation, 2020, Epilepsia
  • Toward a better definition of focal cortical dysplasia: An iterative histopathological and genetic agreement trial, 2021, Epilepsia
  • Evidence of a Rapid Shift in Outpatient Practice During the COVID-19 Pandemic Using Telemedicine, 2020, Telemedicine Journal and e-Health

The scientist collaborates frequently with several coauthors, including Ingmar Blümcke, William Bingaman, Robyn M. Busch, Stephen E. Jones, and Irène Wang, reflecting a sustained network of research partnerships.

Best Publications

  • The clinicopathologic spectrum of focal cortical dysplasias: A consensus classification proposed by an ad hoc Task Force of the ILAE Diagnostic Methods Commission

    Ingmar Blümcke;Maria Thom;Eleonora Aronica;Dawna D. Armstrong

  • Terminology and classification of the cortical dysplasias.

    André Palmini;Imad Najm;G. Avanzini;T. Babb

  • Functional connectivity in the human language system: a cortico-cortical evoked potential study.

    Riki Matsumoto;Dileep R. Nair;Eric LaPresto;Imad Najm

  • Seizure-Promoting Effect of Blood–Brain Barrier Disruption

    Nicola Marchi;Lilyana Angelov;Thomas Masaryk;Vincent Fazio

  • The epileptogenic zone: general principles

    Hans O Lüders;Imad Najm;Dileep Nair;Peter Widdess-Walsh

  • Surgical outcome and prognostic factors of frontal lobe epilepsy surgery

    Lara E. Jeha;Imad Najm;William Bingaman;Dudley Dinner

  • Is SEEG safe? A systematic review and meta-analysis of stereo-electroencephalography–related complications

    Jeffrey P. Mullin;Michael Shriver;Soha Alomar;Imad Najm

  • The ILAE consensus classification of focal cortical dysplasia: An update proposed by an ad hoc task force of the ILAE diagnostic methods commission

    Unknown

  • Complications of invasive video-EEG monitoring with subdural grid electrodes.

    H.M. Hamer;H.H. Morris;E.J. Mascha;M.T. Karafa

  • The localizing value of ictal EEG in focal epilepsy

    N. Foldvary;G. Klem;J. Hammel;W. Bingaman

  • Somatic Mutations Activating the mTOR Pathway in Dorsal Telencephalic Progenitors Cause a Continuum of Cortical Dysplasias

    Alissa M. D’Gama;Alissa M. D’Gama;Alissa M. D’Gama;Mollie B. Woodworth;Mollie B. Woodworth;Mollie B. Woodworth;Amer A. Hossain;Amer A. Hossain;Amer A. Hossain;Sara Bizzotto;Sara Bizzotto;Sara Bizzotto

  • Technique, Results, and Complications Related to Robot-Assisted Stereoelectroencephalography.

    Jorge González-Martínez;Juan Bulacio;Susan Thompson;John Gale

  • Antagonism of peripheral inflammation reduces the severity of status epilepticus

    Nicola Marchi;Qingyuan Fan;Chaitali Ghosh;Vincent Fazio

  • Stereoelectroencephalography in the "difficult to localize" refractory focal epilepsy: early experience from a North American epilepsy center.

    Jorge Gonzalez-Martinez;Juan Bulacio;Andreas Alexopoulos;Lara Jehi

  • Predictors of outcome after temporal lobectomy for the treatment of intractable epilepsy

    L. E. Jeha;I. M. Najm;W. E. Bingaman;F. Khandwala

  • Regionally specific and rapid increases in brain-derived neurotrophic factor messenger RNA in the adult rat brain following seizures induced by systemic administration of kainic acid

    M. M. Dugich-djordjevic;G. Tocco;P. A. Lapchak;G. M. pasinetti

  • Temporal lobe epilepsy due to hippocampal sclerosis in pediatric candidates for epilepsy surgery

    A. Mohamed;Elaine Wyllie;P. Ruggieri;P. Kotagal

  • Development and validation of nomograms to provide individualised predictions of seizure outcomes after epilepsy surgery: a retrospective analysis.

    Lara Jehi;Ruta Yardi;Kevin Chagin;Laura Tassi

  • Ripple classification helps to localize the seizure-onset zone in neocortical epilepsy.

    Shuang Wang;Shuang Wang;Irene Z. Wang;Juan C. Bulacio;John C. Mosher

  • Textbook of Epilepsy Surgery

    Imad M. Najm;William Bongaman;Hans Luders

  • Seizure outcome after epilepsy surgery in patients with normal preoperative MRI

    K. Chapman;Elaine Wyllie;Imad Najm;P. Ruggieri

  • BDNF mRNA expression in the developing rat brain following kainic acid-induced seizure activity

    Millicent M. Dugich-Djordjevic;Georges Tocco;David A. Willoughby;Imad Najm

Frequent Co-Authors

William Bingaman
William Bingaman Cleveland Clinic
Jorge Gonzalez-Martinez
Jorge Gonzalez-Martinez Cleveland Clinic
Hans Lüders
Hans Lüders Case Western Reserve University
Lara Jehi
Lara Jehi Cleveland Clinic
Juan Bulacio
Juan Bulacio Cleveland Clinic
Andreas V. Alexopoulos
Andreas V. Alexopoulos Cleveland Clinic
Dileep Nair
Dileep Nair Cleveland Clinic
Elaine Wyllie
Elaine Wyllie Cleveland Clinic
Thomas L. Babb
Thomas L. Babb Wayne State University
Beate Diehl
Beate Diehl University College London

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