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Medicine

D-Index
121
Citations
67309
World Ranking
3559
National Ranking
357

Overview

Philip Quirke is affiliated with the University of Leeds in the United Kingdom and specializes in the field of Medicine with a significant focus on oncology and surgical treatments related to colorectal cancer. Their scholarly contributions encompass various aspects of cancer research, with a particular emphasis on colorectal cancer surgical treatments, screening and detection, and related genetic factors.

Quirke has published extensively in several prominent scientific journals. Frequent publication venues include:

  • British Journal of Surgery
  • Journal of Clinical Oncology
  • Annals of Oncology
  • The Journal of Pathology
  • bioRxiv (Cold Spring Harbor Laboratory)

The scientist has collaborated regularly with several co-authors, notably:

  • Nicholas P. West
  • Susan D. Richman
  • Henry M. Wood
  • Michel Seymour
  • Tim Maughan

Philip Quirke's research spans multiple subfields within medicine, including:

  • Oncology
  • Surgery
  • Pulmonary and Respiratory Medicine
  • Cancer Research
  • Pathology and Forensic Medicine

The main topics addressed in Quirke's body of work are:

  • Colorectal Cancer Surgical Treatments
  • Colorectal Cancer Screening and Detection
  • Colorectal Cancer Treatments and Studies
  • Genetic factors in colorectal cancer
  • Radiomics and Machine Learning in Medical Imaging
  • Cancer Genomics and Diagnostics
  • Gastric Cancer Management and Outcomes

Notable recent publications authored or co-authored by Philip Quirke include:

  • Localised colon cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up (2020, Annals of Oncology)
  • Mutational signature in colorectal cancer caused by genotoxic pks+ E. coli (2020, Nature)
  • Preoperative Chemotherapy for Operable Colon Cancer: Mature Results of an International Randomized Controlled Trial (2023, Journal of Clinical Oncology)
  • Clinical-Grade Detection of Microsatellite Instability in Colorectal Tumors by Deep Learning (2020, Gastroenterology)
  • Image-based consensus molecular subtype (imCMS) classification of colorectal cancer using deep learning (2020, Gut)

Best Publications

  • Short-term endpoints of conventional versus laparoscopic-assisted surgery in patients with colorectal cancer (MRC CLASICC trial): multicentre, randomised controlled trial

    Pierre J Guillou;Philip Quirke;Helen Thorpe;Joanne Walker

  • Local recurrence of rectal adenocarcinoma due to inadequate surgical resection. Histopathological study of lateral tumour spread and surgical excision.

    P. Quirke;M.F. Dixon;P. Durdey;N.S. Williams

  • Randomized trial of laparoscopic-assisted resection of colorectal carcinoma: 3-year results of the UK MRC CLASICC Trial Group.

    David G. Jayne;Pierre J. Guillou;Helen Thorpe;Philip Quirke

  • Preoperative radiotherapy versus selective postoperative chemoradiotherapy in patients with rectal cancer (MRC CR07 and NCIC-CTG C016): a multicentre, randomised trial

    David Sebag-Montefiore;Richard J. Stephens;Robert Steele;John Monson

  • Five‐year follow‐up of the Medical Research Council CLASICC trial of laparoscopically assisted versus open surgery for colorectal cancer

    D G Jayne;H C Thorpe;J Copeland;P Quirke

  • Role of circumferential margin involvement in the local recurrence of rectal cancer

    I J Adam;M O Mohamdee;I G Martin;N Scott

  • Effect of the plane of surgery achieved on local recurrence in patients with operable rectal cancer: a prospective study using data from the MRC CR07 and NCIC-CTG CO16 randomised clinical trial

    Phil Quirke;Phil Quirke;Robert Steele;John Monson;Robert Grieve

  • What Is the Role for the Circumferential Margin in the Modern Treatment of Rectal Cancer

    Iris D. Nagtegaal;Phil Quirke

  • Kirsten ras mutations in patients with colorectal cancer: the ‘RASCAL II’ study

    H. J. N. Andreyev;A. R. Norman;D. Cunningham;J. Oates

  • Mutational signature in colorectal cancer caused by genotoxic pks+ E. coli.

    Cayetano Pleguezuelos-Manzano;Jens Puschhof;Axel Rosendahl Huber;Arne van Hoeck

  • Macroscopic Evaluation of Rectal Cancer Resection Specimen: Clinical Significance of the Pathologist in Quality Control

    Iris D. Nagtegaal;Cornelis J.H. van de Velde;Erik van der Worp;Ellen Kapiteijn

  • Complete Mesocolic Excision With Central Vascular Ligation Produces an Oncologically Superior Specimen Compared With Standard Surgery for Carcinoma of the Colon

    Nicholas P. West;Werner Hohenberger;Klaus Weber;Aristoteles Perrakis

  • Recommendations for reporting tumor budding in colorectal cancer based on the International Tumor Budding Consensus Conference (ITBCC) 2016.

    Alessandro Lugli;Richard Kirsch;Yoichi Ajioka;Fred Bosman

  • Rates of Circumferential Resection Margin Involvement Vary Between Surgeons and Predict Outcomes in Rectal Cancer Surgery

    Kevin F. Birbeck;Christopher P. Macklin;Nicholas J. Tiffin;Wendy Parsons

  • Long-term follow-up of the Medical Research Council CLASICC trial of conventional versus laparoscopically assisted resection in colorectal cancer

    B L Green;H C Marshall;F Collinson;P Quirke

  • KRAS and BRAF Mutations in Advanced Colorectal Cancer Are Associated With Poor Prognosis but Do Not Preclude Benefit From Oxaliplatin or Irinotecan: Results From the MRC FOCUS Trial

    Susan D. Richman;Matthew T. Seymour;Philip Chambers;Faye Elliott

  • Value of Mismatch Repair, KRAS, and BRAF Mutations in Predicting Recurrence and Benefits From Chemotherapy in Colorectal Cancer

    Gordon Hutchins;Katie Southward;Kelly Handley;Laura Magill

  • Low Rectal Cancer: A Call for a Change of Approach in Abdominoperineal Resection

    Iris D. Nagtegaal;Cornelius J.H. van de Velde;Corrie A.M. Marijnen;Jan H.J.M. van Krieken

  • Mismatch Repair Status and BRAF Mutation Status in Metastatic Colorectal Cancer Patients: A Pooled Analysis of the CAIRO, CAIRO2, COIN, and FOCUS Studies

    Sabine Venderbosch;Iris D Nagtegaal;Timothy S Maughan;Christopher G Smith

  • Magnetic Resonance Imaging–Detected Tumor Response for Locally Advanced Rectal Cancer Predicts Survival Outcomes: MERCURY Experience

    Uday B. Patel;Fiona Taylor;Lennart Blomqvist;Christopher George

Frequent Co-Authors

Michael F. Dixon
Michael F. Dixon University of Leeds
Gina Brown
Gina Brown Imperial College London
Richard Gray
Richard Gray University of Oxford
Iris D. Nagtegaal
Iris D. Nagtegaal Radboud University
Graham R. Taylor
Graham R. Taylor Imperial College London
Julia Brown
Julia Brown University of Leeds
Brendan J. Moran
Brendan J. Moran University of New South Wales
David J. Kerr
David J. Kerr University of Oxford
Jennifer H. Barrett
Jennifer H. Barrett University of Leeds
Werner Hohenberger
Werner Hohenberger University of Erlangen-Nuremberg

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