George S. Bloom

Research.com Recognitions

• 2016 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Best Publications

• Amyloid-β and Tau: The Trigger and Bullet in Alzheimer Disease Pathogenesis

  George S. Bloom

  2082
  Citations

• Submolecular domains of bovine brain kinesin identified by electron microscopy and monoclonal antibody decoration

  Nobutaka Hirokawa;K.Kevin Pfister;Hiroshi Yorifuji;Mark C. Wagner

  614
  Citations

• Regulation of the phosphorylation state and microtubule-binding activity of Tau by protein phosphatase 2A.

  Estelle Sontag;Viyada Nunbhakdi-Craig;Gloria Lee;George S. Bloom

  565
  Citations

• Dissociation of a 110-kD peripheral membrane protein from the Golgi apparatus is an early event in brefeldin A action.

  J G Donaldson;J Lippincott-Schwartz;G S Bloom;T E Kreis

  523
  Citations

• Prion-like behaviour and tau-dependent cytotoxicity of pyroglutamylated amyloid-β

  Justin M. Nussbaum;Stephan Schilling;Holger Cynis;Antonia Silva

  514
  Citations

• A novel pool of protein phosphatase 2A is associated with microtubules and is regulated during the cell cycle.

  E Sontag;Nunbhakdi-Craig;G S Bloom;M C Mumby

  438
  Citations

• Molecular Interactions among Protein Phosphatase 2A, Tau, and Microtubules IMPLICATIONS FOR THE REGULATION OF TAU PHOSPHORYLATION AND THE DEVELOPMENT OF TAUOPATHIES

  Estelle Sontag;Viyada Nunbhakdi-Craig;Gloria Lee;Roland Brandt

  389
  Citations

• Dual control of caveolar membrane traffic by microtubules and the actin cytoskeleton

  Dorothy I. Mundy;Thomas Machleidt;Yun Shu Ying;Richard G W Anderson

  388
  Citations

• Native structure and physical properties of bovine brain kinesin and identification of the ATP-binding subunit polypeptide.

  George S. Bloom;Mark C. Wagner;K. Kevin Pfister;Scott T. Brady

  372
  Citations

• Kinesin is the motor for microtubule-mediated Golgi-to-ER membrane traffic.

  Jennifer Lippincott-Schwartz;Nelson B. Cole;Alex Marotta;Patricia A. Conrad

  359
  Citations

• Caveolin cycles between plasma membrane caveolae and the Golgi complex by microtubule-dependent and microtubule-independent steps.

  Patricia A. Conrad;Eric J. Smart;Yun Shu Ying;Richard G W Anderson

  352
  Citations

• Monoclonal antibodies to kinesin heavy and light chains stain vesicle-like structures, but not microtubules, in cultured cells.

  K. K. Pfister;M. C. Wagner;D. L. Stenoien;Scott T. Brady

  350
  Citations

• Kinesin associates with anterogradely transported membranous organelles in vivo

  Nobutaka Hirokawa;Reiko Sato-Yoshitake;Naoto Kobayashi;K. Kevin Pfister

  347
  Citations

• IQGAP1, a Rac- and Cdc42-binding protein, directly binds and cross- links microfilaments

  Anne Marie Bashour;Aaron T. Fullerton;Matthew J. Hart;George S. Bloom

  332
  Citations

• A monoclonal antibody against kinesin inhibits both anterograde and retrograde fast axonal transport in squid axoplasm.

  Scott T. Brady;K. Kevin Pfister;George S. Bloom

  326
  Citations

• Mechanisms of Fast and Slow Axonal Transport

  R B Vallee;G S Bloom

  319
  Citations

• Widespread distribution of the major polypeptide component of MAP 1 (microtubule-associated protein 1) in the nervous system.

  G S Bloom;T A Schoenfeld;R B Vallee

  305
  Citations

• A novel 58-kDa protein associates with the Golgi apparatus and microtubules.

  G S Bloom;T A Brashear

  304
  Citations

• IQGAP1, a Novel Vascular Endothelial Growth Factor Receptor Binding Protein, Is Involved in Reactive Oxygen Species—Dependent Endothelial Migration and Proliferation

  Minako Yamaoka-Tojo;Masuko Ushio-Fukai;Lula Hilenski;Sergey I. Dikalov

  287
  Citations

• Association of microtubule-associated protein 2 (MAP 2) with microtubules and intermediate filaments in cultured brain cells.

  George S. Bloom;Richard B. Vallee

  271
  Citations