World's Best Scientists 2026 revealed!

D-Index & Metrics

Medicine

D-Index
83
Citations
27585
World Ranking
15526
National Ranking
7827

Research.com Recognitions

  • 2013 - Fellow of the American Association for the Advancement of Science (AAAS)
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians

Overview

MacRae F. Linton is affiliated with Vanderbilt University in the United States and has contributed extensively to the fields of medicine and biochemistry, genetics, and molecular biology. Their research primarily focuses on molecular biology, surgery, immunology, cancer research, and cardiology and cardiovascular medicine.

Linton has published numerous papers addressing key aspects of lipoproteins, atherosclerosis, cardiovascular diseases, and lipid metabolism. Prominent topics in their work include lipoproteins and cardiovascular health, RNA modifications and cancer, atherosclerosis and cardiovascular diseases, RNA research and splicing, cholesterol and lipid metabolism, diabetes, cardiovascular risks and lipoproteins, as well as immune cells in cancer.

Their recent notable publications include:

  • "HDL Function and Atherosclerosis: Reactive Dicarbonyls as Promising Targets of Therapy," 2023, published in Circulation Research
  • "Macrophage SR-BI modulates autophagy via VPS34 complex and PPARα transcription of Tfeb in atherosclerosis," 2021, published in Journal of Clinical Investigation
  • "Scavenging of reactive dicarbonyls with 2-hydroxybenzylamine reduces atherosclerosis in hypercholesterolemic Ldlr−/− mice," 2020, published in Nature Communications
  • "Epsin Nanotherapy Regulates Cholesterol Transport to Fortify Atheroma Regression," 2022, published in Circulation Research
  • "Targeting Epsins to Inhibit Fibroblast Growth Factor Signaling While Potentiating Transforming Growth Factor-β Signaling Constrains Endothelial-to-Mesenchymal Transition in Atherosclerosis," 2023, published in Circulation

Linton frequently collaborates with colleagues including Kasey C. Vickers, Danielle L. Michell, Quanhu Sheng, Patricia G. Yancey, and Sean S. Davies, contributing to a wide network of research partnerships.

Publication venues where Linton's work regularly appears include:

  • Arteriosclerosis Thrombosis and Vascular Biology (12 publications)
  • Circulation (8 publications)
  • bioRxiv (Cold Spring Harbor Laboratory) (7 publications)
  • Journal of Clinical Lipidology (4 publications)
  • Journal of Lipid Research (3 publications)

Among distinctions, Linton was named a Fellow of the American Association for the Advancement of Science (AAAS) in 2013 and is a member of the Association of American Physicians.

Best Publications

  • Current Perspectives on Statins

    David J. Maron;Sergio Fazio;MacRae F. Linton

  • Premature coronary-artery atherosclerosis in systemic lupus erythematosus.

    Yu Asanuma;Annette Oeser;Ayumi K. Shintani;Elizabeth Turner

  • Treatment of diabetes and atherosclerosis by inhibiting fatty-acid-binding protein aP2

    Masato Furuhashi;Gürol Tuncman;Cem Z. Görgün;Liza Makowski;Liza Makowski

  • Lack of macrophage fatty-acid-binding protein aP2 protects mice deficient in apolipoprotein E against atherosclerosis.

    Liza Makowski;Jeffrey B. Boord;Kazuhisa Maeda;Vladimir R. Babaev

  • Prevention of atherosclerosis in apolipoprotein E-deficient mice by bone marrow transplantation

    MacRae F. Linton;James B. Atkinson;Sergio Fazio

  • Disruption of the 12/15-lipoxygenase gene diminishes atherosclerosis in apo E-deficient mice.

    Tillmann Cyrus;Joseph L. Witztum;Daniel J. Rader;Rajendra Tangirala

  • Reducing endoplasmic reticulum stress through a macrophage lipid chaperone alleviates atherosclerosis

    Ebru Erbay;Vladimir R. Babaev;Jared R. Mayers;Liza Makowski

  • Clinical Genetic Testing for Familial Hypercholesterolemia: JACC Scientific Expert Panel.

    Amy C. Sturm;Joshua W. Knowles;Samuel S. Gidding;Zahid S. Ahmad

  • B-Lymphocyte Deficiency Increases Atherosclerosis in LDL Receptor–Null Mice

    Amy S. Major;Sergio Fazio;MacRae F. Linton

  • Residual Cardiovascular Risk Despite Optimal LDL-Cholesterol Reduction with Statins: The Evidence, Etiology, and Therapeutic Challenges

    Uchechukwu K. Sampson;Sergio Fazio;MacRae F. Linton

  • Cyclooxygenase-2 Promotes Early Atherosclerotic Lesion Formation in LDL Receptor–Deficient Mice

    Michael E. Burleigh;Vladimir R. Babaev;John A. Oates;Raymond C. Harris

  • Phenotypes of apolipoprotein B and apolipoprotein E after liver transplantation.

    M F Linton;R Gish;S T Hubl;E Bütler

  • Macrophages, inflammation, and atherosclerosis

    MacRae F Linton;Sergio Fazio

  • Increased atherosclerosis in mice reconstituted with apolipoprotein E null macrophages

    Sergio Fazio;Vladimir R. Babaev;Alisa B. Murray;Alyssa H. Hasty

  • The relationship between dose of vitamin E and suppression of oxidative stress in humans

    L. Jackson Roberts;John A. Oates;MacRae F. Linton;Sergio Fazio

  • The Role of Lipids and Lipoproteins in Atherosclerosis

    MacRae F Linton;Patricia G Yancey;Sean S Davies;W. Gray Jerome

  • Transgenic mice expressing high plasma concentrations of human apolipoprotein B100 and lipoprotein(a).

    MacRae F. Linton;Robert V. Farese;Giulia Chiesa;David S. Grass

  • Reduced macrophage apoptosis is associated with accelerated atherosclerosis in low-density lipoprotein receptor-null mice

    June Liu;Douglas P. Thewke;Yan Ru Su;MacRae F. Linton

  • Increased atherosclerosis in LDL receptor–null mice lacking ACAT1 in macrophages

    Sergio Fazio;Amy S. Major;Larry L. Swift;Linda A. Gleaves

  • Massive xanthomatosis and altered composition of atherosclerotic lesions in hyperlipidemic mice lacking acyl CoA:cholesterol acyltransferase 1.

    Michel Accad;Steven J. Smith;Steven J. Smith;Dale L. Newland;David A. Sanan

Frequent Co-Authors

Sergio Fazio
Sergio Fazio Oregon Health & Science University
Alyssa H. Hasty
Alyssa H. Hasty Vanderbilt University
Stephen G. Young
Stephen G. Young University of California, Los Angeles
Agnes B. Fogo
Agnes B. Fogo Vanderbilt University Medical Center
John A. Oates
John A. Oates Vanderbilt University
C. Michael Stein
C. Michael Stein Vanderbilt University Medical Center
Daniel J. Rader
Daniel J. Rader University of Pennsylvania
James M. May
James M. May Vanderbilt University Medical Center
Christie M. Ballantyne
Christie M. Ballantyne Baylor College of Medicine
Xiao-Ou Shu
Xiao-Ou Shu Vanderbilt University Medical Center

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Pursuing a medical degree in the USA opens up numerous healthcare career opportunities, both clinical and administrative. For those who wish to enter the workforce quickly, exploring 6 month lpn program options can be a great stepping stone into nursing, offering a fast-track route to licensed practical nursing positions.

If you already hold a nursing degree and want to specialize, consider the msn to pmhnp online pathway. This allows registered nurses to become Psychiatric Mental Health Nurse Practitioners, a field in high demand across the U.S.

For those interested in healthcare management rather than direct patient care, there are affordable and flexible educational pathways as well. An online healthcare administration degree equips students for a range of leadership roles in hospitals, clinics, and public health organizations.

Advancing further, an affordable mha online programs can help current professionals gain the skills needed for executive positions in health systems. Wherever your interests lie, online programs provide the flexibility to pursue a healthcare career that matches your goals.

Best Scientists Citing MacRae F. Linton

Trending Scientists