His scientific interests lie mostly in Immunology, Immune system, T cell, Innate lymphoid cell and Innate immune system. His Immunology research is multidisciplinary, incorporating perspectives in Inflammatory bowel disease and Pathology. His Inflammatory bowel disease research is multidisciplinary, incorporating elements of Colitis and Ulcerative colitis.
His research investigates the connection between Immune system and topics such as Antigen that intersect with problems in Cell function. His research integrates issues of Homeostasis, Immunity and Effector in his study of Inflammation. His study in Interleukin 21 is interdisciplinary in nature, drawing from both IL-2 receptor and Interleukin 10.
Kevin J. Maloy mostly deals with Immunology, Immune system, Inflammatory bowel disease, Inflammation and T cell. His work is connected to Innate lymphoid cell, Immunity, Innate immune system, Interleukin 23 and IL-2 receptor, as a part of Immunology. The Immune system study combines topics in areas such as Cell biology, Disease, Pathology and Antigen.
His Inflammatory bowel disease research is multidisciplinary, relying on both Tumor necrosis factor alpha, Colitis and Ulcerative colitis. His Inflammation study combines topics in areas such as Interleukin, Intestinal mucosa and Effector. He has researched T cell in several fields, including Molecular biology and Cytokine.
His primary areas of study are Immune system, Disease, Inflammatory bowel disease, Computational biology and Microbiology. His Immune system research integrates issues from Inflammation, Virulence and Cell biology. He combines subjects such as T cell, Homeostasis and Metabolism with his study of Inflammation.
His work deals with themes such as Tumor necrosis factor alpha, Cancer research, Crohn's disease and Colitis, which intersect with Inflammatory bowel disease. His Microbiology research includes themes of Extracellular and Bacteria. He mostly deals with Antigen in his studies of Immunology.
Kevin J. Maloy mainly investigates Disease, Crohn's disease, Inflammatory bowel disease, Tumor necrosis factor alpha and Autophagy. The various areas that Kevin J. Maloy examines in his Disease study include Microbiome, Immune homeostasis, Gut flora and Computational biology. Kevin J. Maloy interconnects Apoptosis, Colitis, Immunology and Ulcerative colitis in the investigation of issues within Crohn's disease.
His study on ATG16L1 is often connected to Helicobacter hepaticus as part of broader study in Inflammatory bowel disease.
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Intestinal homeostasis and its breakdown in inflammatory bowel disease
Kevin J. Maloy;Fiona Powrie;Fiona Powrie.
Regulatory T cells in the control of immune pathology.
Kevin J. Maloy;Fiona Powrie.
Nature Immunology (2001)
Innate lymphoid cells drive interleukin-23-dependent innate intestinal pathology
Sofia Buonocore;Philip P. Ahern;Holm H. Uhlig;Ivaylo I. Ivanov.
Interleukin-23 drives innate and T cell–mediated intestinal inflammation
Sophie Hue;Philip P Ahern;Sofia Buonocore;Marika C. Kullberg.
Journal of Experimental Medicine (2006)
CD4+CD25+ T(R) cells suppress innate immune pathology through cytokine-dependent mechanisms.
Kevin J. Maloy;Laurence Salaun;Rachel Cahill;Gordon Dougan.
Journal of Experimental Medicine (2003)
IL-23 plays a key role in Helicobacter hepaticus-induced T cell-dependent colitis
Marika C. Kullberg;Dragana Jankovic;Carl G. Feng;Sophie Hue.
Journal of Experimental Medicine (2006)
IL-1β mediates chronic intestinal inflammation by promoting the accumulation of IL-17A secreting innate lymphoid cells and CD4+ Th17 cells
Margherita Coccia;Oliver J. Harrison;Chris Schiering;Chris Schiering;Mark J. Asquith.
Journal of Experimental Medicine (2012)
Interleukin-23 Drives Intestinal Inflammation through Direct Activity on T Cells
Philip P. Ahern;Chris Schiering;Chris Schiering;Sofia Buonocore;Mandy J. McGeachy.
Oncostatin M drives intestinal inflammation and predicts response to tumor necrosis factor-neutralizing therapy in patients with inflammatory bowel disease
N R West;A N Hegazy;Owens Bmj.;S J Bullers.
Nature Medicine (2017)
Interleukin-23 Restrains Regulatory T Cell Activity to Drive T Cell-Dependent Colitis
Ana Izcue;Sophie Hue;Sofia Buonocore;Carolina V. Arancibia-Cárcamo.
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