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Immunology

D-Index
89
Citations
56830
World Ranking
1094
National Ranking
587

Medicine

D-Index
89
Citations
56841
World Ranking
12414
National Ranking
6354

Overview

Frederic Geissmann is affiliated with the Memorial Sloan Kettering Cancer Center in the United States. Their research primarily spans the fields of Medicine, Immunology and Microbiology, and Neuroscience. In particular, their work significantly contributes to subfields such as Immunology, Molecular Biology, Physiology, Neurology, and Hematology.

Their research concentrates on several core topics including immune cells in cancer, neuroinflammation and neurodegeneration mechanisms, phagocytosis and immune regulation, erythrocyte function and pathophysiology, extracellular vesicles in disease, acute myeloid leukemia research, and nuclear receptors and signaling.

Frederic Geissmann has authored numerous scientific papers published across a variety of influential venues. Frequent publication outlets include bioRxiv (Cold Spring Harbor Laboratory), Nature, eLife, Science Immunology, and Nature Neuroscience.

Notable recent publications include:

  • "The nuclear factor ID3 endows macrophages with a potent anti-tumour activity," 2024, Nature
  • "Physiology and diseases of tissue-resident macrophages," 2023, Nature
  • "Inborn errors of OAS-RNase L in SARS-CoV-2-related multisystem inflammatory syndrome in children," 2022, Science
  • "Origins, Biology, and Diseases of Tissue Macrophages," 2021, Annual Review of Immunology
  • "Cxcr4 distinguishes HSC-derived monocytes from microglia and reveals monocyte immune responses to experimental stroke," 2020, Nature Neuroscience

Their research collaborations include frequent co-authorship with:

  • Tomi Lazarov
  • Bertrand Boisson
  • Ting Zhou
  • Rocío Vicario
  • Olivier Elemento

Frederic Geissmann's research has produced a body of work important to understanding immune system cell functions in cancer and neurological disease contexts, exploring mechanisms of macrophage biology, and investigating immune responses at the molecular and cellular levels.

Best Publications

  • Blood Monocytes Consist of Two Principal Subsets with Distinct Migratory Properties

    Frederic Geissmann;Steffen Jung;Dan R. Littman

  • Development of Monocytes, Macrophages, and Dendritic Cells

    Frederic Geissmann;Markus G. Manz;Steffen Jung;Michael H. Sieweke

  • A Lineage of Myeloid Cells Independent of Myb and Hematopoietic Stem Cells

    Christian Schulz;Elisa Gomez Perdiguero;Laurent Chorro;Heather Szabo-Rogers

  • Tissue-resident macrophages originate from yolk-sac-derived erythro-myeloid progenitors

    Elisa Gomez Perdiguero;Kay Klapproth;Christian Schulz;Katrin Busch

  • Monitoring of blood vessels and tissues by a population of monocytes with patrolling behavior.

    Cedric Auffray;Darin Fogg;Meriem Garfa;Gaelle Elain

  • Blood monocytes: development, heterogeneity, and relationship with dendritic cells.

    Cedric Auffray;Michael H Sieweke;Frederic Geissmann

  • Activation-induced cytidine deaminase (AID) deficiency causes the autosomal recessive form of the Hyper-IgM syndrome (HIGM2).

    Patrick Revy;Taro Muto;Yves Levy;Frédéric Geissmann

  • Microglia emerge from erythromyeloid precursors via Pu.1- and Irf8-dependent pathways

    Katrin Kierdorf;Daniel Erny;Tobias Goldmann;Victor Sander

  • Human CD14dim monocytes patrol and sense nucleic acids and viruses via TLR7 and TLR8 receptors.

    Jérôme Cros;Nicolas Cagnard;Kevin Woollard;Natacha Patey

  • Environment Drives Selection and Function of Enhancers Controlling Tissue-Specific Macrophage Identities

    David Gosselin;Verena M. Link;Casey E. Romanoski;Gregory J. Fonseca

  • A Clonogenic Bone Marrow Progenitor Specific for Macrophages and Dendritic Cells

    Darin K. Fogg;Claire Sibon;Chaouki Miled;Steffen Jung

  • TLR3 deficiency in patients with herpes simplex encephalitis.

    Shen Ying Zhang;Shen Ying Zhang;Emmanuelle Jouanguy;Emmanuelle Jouanguy;Sophie Ugolini;Asma Smahi

  • Constant replenishment from circulating monocytes maintains the macrophage pool in the intestine of adult mice

    Calum C Bain;Alberto Bravo-Blas;Charlotte L Scott;Elisa Gomez Perdiguero

  • Origin, fate and dynamics of macrophages at central nervous system interfaces.

    Tobias Goldmann;Peter Wieghofer;Marta Joana Costa Jordão;Fabiola Prutek

  • Monocytes in atherosclerosis: subsets and functions.

    Kevin J. Woollard;Frederic Geissmann

  • X-linked anhidrotic ectodermal dysplasia with immunodeficiency is caused by impaired NF-kappaB signaling.

    Rainer Döffinger;Asma Smahi;Christine Bessia;Frédéric Geissmann

  • Specification of tissue-resident macrophages during organogenesis

    Elvira Mass;Ivan Ballesteros;Matthias Farlik;Florian Halbritter

  • Herpes simplex virus encephalitis in human UNC-93B deficiency.

    Armanda Casrouge;Shen Ying Zhang;Shen Ying Zhang;Céline Eidenschenk;Emmanuelle Jouanguy;Emmanuelle Jouanguy

  • Nr4a1-dependent Ly6C(low) monocytes monitor endothelial cells and orchestrate their disposal.

    Leo M. Carlin;Efstathios G. Stamatiades;Cedric Auffray;Richard N. Hanna

  • Monocytes give rise to mucosal, but not splenic, conventional dendritic cells

    Chen Varol;Limor Landsman;Darin K. Fogg;Liat Greenshtein

Frequent Co-Authors

Laurent Abel
Laurent Abel Université Paris Cité
Jean-Laurent Casanova
Jean-Laurent Casanova The University of Texas Southwestern Medical Center
Stéphanie Boisson-Dupuis
Stéphanie Boisson-Dupuis Université Paris Cité
Emmanuelle Jouanguy
Emmanuelle Jouanguy Necker-Enfants Malades Hospital
Alain Fischer
Alain Fischer Collège de France
Capucine Picard
Capucine Picard Université Paris Cité
Stuart G. Tangye
Stuart G. Tangye Garvan Institute of Medical Research
Cindy S. Ma
Cindy S. Ma Garvan Institute of Medical Research
Lluis Quintana-Murci
Lluis Quintana-Murci Institut Pasteur

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Related Online Degrees & Career Pathways

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