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Medicine

D-Index
81
Citations
23981
World Ranking
16659
National Ranking
8361

Overview

H. Lester Kirchner is affiliated with the Geisinger Health System in the United States. Their research primarily falls within the field of Medicine, with a focus on several subfields including Cardiology and Cardiovascular Medicine, Surgery, Epidemiology, Nephrology, and Genetics.

The scientist's recent publications include the following works:

  • The risk of tuberculosis in children after close exposure: a systematic review and individual-participant meta-analysis, 2020, The Lancet
  • Prediction of mortality from 12-lead electrocardiogram voltage data using a deep neural network, 2020, Nature Medicine
  • Deep Neural Networks Can Predict New-Onset Atrial Fibrillation From the 12-Lead ECG and Help Identify Those at Risk of Atrial Fibrillation-Related Stroke, 2021, Circulation
  • Estimated Glomerular Filtration Rate, Albuminuria, and Adverse Outcomes, 2023, JAMA
  • Clinical outcomes of a genomic screening program for actionable genetic conditions, 2020, Genetics in Medicine

Kirchner frequently publishes in venues such as Circulation, bioRxiv (Cold Spring Harbor Laboratory), JAMA, Genetics in Medicine, and the Journal of the American Society of Nephrology. These journals reflect the scientist's interdisciplinary approach connecting cardiovascular health, genetics, kidney diseases, and epidemiology.

Frequent coauthors associated with Kirchner's work include:

  • Amy C. Sturm
  • Yirui Hu
  • Melissa Kelly
  • Laney K. Jones
  • Marc S. Williams

The main topics covered in Kirchner's research are diverse and include:

  • Lipoproteins and Cardiovascular Health
  • Tuberculosis Research and Epidemiology
  • Chronic Kidney Disease and Diabetes
  • Health Systems, Economic Evaluations, Quality of Life
  • Mycobacterium Research and Diagnosis
  • Posttraumatic Stress Disorder Research
  • Dialysis and Renal Disease Management

Kirchner's body of work reflects an integration of clinical and epidemiological methods applied across complex diseases, with particular interest in cardiovascular conditions, renal health, infectious diseases, and genomic medicine. The collaboration with experts in cardiology, genetics, and epidemiology supports a multidisciplinary investigative approach to addressing diverse health challenges.

Best Publications

  • Association of nocturnal arrhythmias with sleep-disordered breathing: The sleep heart health study

    Reena Mehra;Emelia J. Benjamin;Eyal Shahar;Daniel J. Gottlieb

  • Genetic and Pharmacologic Inactivation of ANGPTL3 and Cardiovascular Disease

    Frederick E Dewey;Viktoria Gusarova;Richard L Dunbar;Colm T O'Dushlaine

  • Prevalence and risk factors for sleep-disordered breathing in 8- to 11-year-old children: association with race and prematurity.

    Carol Lynn Rosen;Emma K. Larkin;H. Lester Kirchner;Judith L. Emancipator

  • The Effects of Age, Sex, Ethnicity, and Sleep-Disordered Breathing on Sleep Architecture

    Susan Redline;H. Lester Kirchner;Stuart F. Quan;Daniel J. Gottlieb

  • Inactivating Variants in ANGPTL4 and Risk of Coronary Artery Disease.

    Frederick E. Dewey;Viktoria Gusarova;Colm O'Dushlaine;Omri Gottesman

  • Increased risk of death and de novo chronic kidney disease following reversible acute kidney injury

    Ion D. Bucaloiu;H Lester Kirchner;Evan R. Norfolk;James E. Hartle

  • Distribution and clinical impact of functional variants in 50,726 whole-exome sequences from the DiscovEHR study

    Frederick E. Dewey;Michael F. Murray;John D. Overton;Lukas Habegger

  • Frequency of voice problems among teachers and other occupations

    Elaine Smith;Jon Lemke;Margaretta Taylor;H. Lester Kirchner

  • Genetic identification of familial hypercholesterolemia within a single U.S. health care system

    Noura S. Abul-Husn;Kandamurugu Manickam;Laney K. Jones;Eric A. Wright

  • Voice problems among teachers: Differences by gender and teaching characteristics

    Elaine Smith;H. Lester Kirchner;Margaretta Taylor;Henry Hoffman

  • The Geisinger MyCode community health initiative: an electronic health record-linked biobank for precision medicine research.

    David J. Carey;Samantha N. Fetterolf;F. Daniel Davis;William A. Faucett

  • PCSK9 genetic variants and risk of type 2 diabetes: a mendelian randomisation study

    Amand F Schmidt;Daniel I Swerdlow;Daniel I Swerdlow;Michael V Holmes;Michael V Holmes;Riyaz S Patel;Riyaz S Patel

  • Association between Metabolic Syndrome and Sleep-disordered Breathing in Adolescents

    Susan Redline;Amy Storfer-Isser;Carol Lynn Rosen;Nathan L. Johnson

  • Variation of C-reactive protein levels in adolescents: association with sleep-disordered breathing and sleep duration.

    Emma K. Larkin;Carol L. Rosen;H. Lester Kirchner;Amy Storfer-Isser

  • Cognitive outcomes of preschool children with prenatal cocaine exposure

    Lynn T. Singer;Sonia Minnes;Elizabeth Short;Robert Arendt

  • Cognitive and Motor Outcomes of Cocaine-Exposed Infants

    Lynn T. Singer;Robert Arendt;Sonia Minnes;Kathleen Farkas

  • Neighborhood disadvantage as a risk factor for pediatric obstructive sleep apnea

    James C Spilsbury;Amy Storfer-Isser;H. Lester Kirchner;Lisa Nelson

  • Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets

    Louise V. Wain;Louise V. Wain;Nick Shrine;María Soler Artigas;A. Mesut Erzurumluoglu

  • Perinatal correlates and neonatal outcomes of small for gestational age infants born at term gestation.

    Benedict A. Doctor;Mary Ann O’Riordan;H.Lester Kirchner;Dinesh Shah

  • Increased behavioral morbidity in school-aged children with sleep-disordered breathing.

    Carol L. Rosen;Amy Storfer-Isser;H. Gerry Taylor;H. Lester Kirchner

Frequent Co-Authors

Susan Redline
Susan Redline Brigham and Women's Hospital
David J. Carey
David J. Carey Geisinger Health System
Lynn T. Singer
Lynn T. Singer Case Western Reserve University
David H. Ledbetter
David H. Ledbetter University of Florida
Richard E. Adams
Richard E. Adams Kent State University
Charles R. Figley
Charles R. Figley Tulane University
Marylyn D. Ritchie
Marylyn D. Ritchie University of Pennsylvania
Elizabeth J. Short
Elizabeth J. Short Case Western Reserve University
Colm O'Dushlaine
Colm O'Dushlaine insitro Inc.
Alan R. Shuldiner
Alan R. Shuldiner University of Maryland, Baltimore

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