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Biology and Biochemistry

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147
Citations
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World Ranking
199
National Ranking
136

Medicine

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147
Citations
108205
World Ranking
1257
National Ranking
729

Overview

Arnold I. Caplan was affiliated with Case Western Reserve University in the United States. Their research extensively covered the fields of medicine, biochemistry, genetics, and molecular biology, with 81 and 26 publications respectively. Key subfields included genetics, molecular biology, pulmonary and respiratory medicine, surgery, and rheumatology.

The main topics of their work included mesenchymal stem cell research, osteoarthritis treatment and mechanisms, tissue engineering and regenerative medicine, neonatal respiratory health research, congenital diaphragmatic hernia studies, respiratory support and mechanisms, as well as RNA and protein synthesis mechanisms.

Notable recent papers authored or coauthored by Caplan included:

  • Umbilical cord mesenchymal stem cells for COVID-19 acute respiratory distress syndrome: A double-blind, phase 1/2a, randomized controlled trial (2021), published in Stem Cells Translational Medicine
  • Mesenchymal Stem Cells Current Clinical Applications: A Systematic Review (2020), published in Archives of Medical Research
  • Cell-based therapy to reduce mortality from COVID-19: Systematic review and meta-analysis of human studies on acute respiratory distress syndrome (2020), published in Stem Cells Translational Medicine
  • An Integrated Multi-Function Heterogeneous Biochemical Circuit for High-Resolution Electrochemistry-Based Genetic Analysis (2020), published in Angewandte Chemie International Edition
  • Engineered nasal cartilage for the repair of osteoarthritic knee cartilage defects (2021), published in Science Translational Medicine

Caplan collaborated frequently with several researchers over the course of their career. Prominent coauthors included Rodrigo A. Somoza, Tracey L. Bonfield, Jean F. Welter, Camillo Ricordi, and David Fletcher.

Their work appeared in medical and scientific journals repeatedly, with frequent publications in the following venues:

  • Tissue Engineering Part A
  • Stem Cells Translational Medicine
  • Journal of Cystic Fibrosis
  • Angewandte Chemie International Edition
  • Frontiers in Bioengineering and Biotechnology

Best Publications

  • Mesenchymal stem cells

    Arnold I. Caplan

  • In vitro chondrogenesis of bone marrow-derived mesenchymal progenitor cells

    Brian Johnstone;Thomas M. Hering;Arnold I. Caplan;Victor M. Goldberg

  • Mesenchymal stem cells as trophic mediators.

    Arnold I. Caplan;James E. Dennis

  • Osteogenic differentiation of purified, culture‐expanded human mesenchymal stem cells in vitro

    Neelam Jaiswal;Stephen E. Haynesworth;Arnold I. Caplan;Scott P. Bruder;Scott P. Bruder

  • Adult mesenchymal stem cells for tissue engineering versus regenerative medicine.

    Arnold I. Caplan

  • Mesenchymal Cell-Based Repair of Large Full Thickness Defects of Articular Cartilage

    Shigeyuki Wakitani;Tatsuhiko Goto;Stephen Pineda;Randell Young

  • Characterization of cells with osteogenic potential from human marrow.

    S.E. Haynesworth;J. Goshima;V.M. Goldberg;A.I. Caplan

  • Myogenic cells derived from rat bone marrow mesenchymal stem cells exposed to 5‐azacytidine

    Shigeyuki Wakitani;Tomoyuki Saito;Arnold I. Caplan

  • The MSC: An Injury Drugstore

    Arnold I. Caplan;Diego Correa

  • Rapid Hematopoietic Recovery After Coinfusion of Autologous-Blood Stem Cells and Culture-Expanded Marrow Mesenchymal Stem Cells in Advanced Breast Cancer Patients Receiving High-Dose Chemotherapy

    Omer N. Koç;Stanton L. Gerson;Brenda W. Cooper;Stephanie M. Dyhouse

  • Mesenchymal stem cells: building blocks for molecular medicine in the 21st century

    Arnold I Caplan;Scott P Bruder

  • Mechanisms involved in the therapeutic properties of mesenchymal stem cells

    Lindolfo da Silva Meirelles;Aparecida Maria Fontes;Dimas Tadeu Covas;Dimas Tadeu Covas;Arnold I. Caplan

  • Why are MSCs therapeutic? New data: new insight

    Arnold I Caplan

  • Mesenchymal stem cell perspective: cell biology to clinical progress

    Mark F. Pittenger;Dennis E. Discher;Bruno M. Péault;Donald G. Phinney

  • A New Human Somatic Stem Cell from Placental Cord Blood with Intrinsic Pluripotent Differentiation Potential

    Gesine Kögler;Sandra Sensken;Judith A. Airey;Thorsten Trapp

  • In search of the in vivo identity of mesenchymal stem cells

    Lindolfo da Silva Meirelles;Arnold I. Caplan;Nance Beyer Nardi

  • Mesenchymal stem cells: environmentally responsive therapeutics for regenerative medicine

    Matthew B Murphy;Kathryn Moncivais;Arnold I Caplan

  • Mesenchymal stem cells in bone development, bone repair, and skeletal regeneration therapy.

    Scott P. Bruder;David J. Fink;David J. Fink;Arnold I. Caplan

  • The Chondrogenic Potential of Human Bone-Marrow-Derived Mesenchymal Progenitor Cells*

    Jung U. Yoo;Traci S. Barthel;Keita Nishimura;Luis Solchaga

  • Mesenchymal Stem Cells The Past, the Present, the Future

    Arnold I. Caplan

Frequent Co-Authors

James E. Dennis
James E. Dennis Baylor College of Medicine
Victor M. Goldberg
Victor M. Goldberg Case Western Reserve University
Brian Johnstone
Brian Johnstone Oregon Health & Science University
Hillard M. Lazarus
Hillard M. Lazarus Case Western Reserve University
Stanton L. Gerson
Stanton L. Gerson Case Western Reserve University
Antonios G. Mikos
Antonios G. Mikos Rice University
Farshid Guilak
Farshid Guilak Washington University in St. Louis
Arthur H. Heuer
Arthur H. Heuer Case Western Reserve University
John Blackwell
John Blackwell Case Western Reserve University
Chung-Chiun Liu
Chung-Chiun Liu Case Western Reserve University

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