World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
73
Citations
18558
World Ranking
5951
National Ranking
2814

Overview

Michael G. Brattain was affiliated with the University of Nebraska Medical Center in the United States. Their research contributions were primarily situated within the fields of Biochemistry, Genetics and Molecular Biology, as well as Medicine.

Their work focused on a number of specific subfields including Cell Biology, Molecular Biology, Pulmonary and Respiratory Medicine, and Oncology. Key research topics covered by Michael G. Brattain included Microtubule and mitosis dynamics, Cellular Mechanics and Interactions, Caveolin-1 and cellular processes, Protein Tyrosine Phosphatases, PI3K/AKT/mTOR signaling in cancer, ATP Synthase and ATPases Research, and Advanced Breast Cancer Therapies.

Michael G. Brattain had several frequent co-authors who appeared consistently in their research publications. These included Premila D. Leiphrakpam, Audrey J. Lazenby, Lynette M. Smith, Chandrakanth Are, and Jennifer D. Black.

Their scholarly work was published mainly in the Journal of Surgical Oncology and Oncotarget. Among their recent papers were:

  • Stathmin expression in metastatic colorectal cancer, 2021, Journal of Surgical Oncology
  • Correlation of PRL3 expression with colorectal cancer progression, 2020, Journal of Surgical Oncology
  • Correction: Characterization of CDK(5) inhibitor, 20-223 (aka CP668863) for colorectal cancer therapy, 2020, Oncotarget

Best Publications

  • Inactivation of the Type II TGF-β Receptor in Colon Cancer Cells with Microsatellite Instability

    Sanford D Markowitz;Jing Wang;Lois Myeroff;Ramon Parsons

  • Heterogeneity of Malignant Cells from a Human Colonic Carcinoma

    Michael G. Brattain;W. David Fine;F. Mahnaz Khaled;Jerry Thompson

  • Mutational Inactivation of Transforming Growth Factor β Receptor Type II in Microsatellite Stable Colon Cancers

    William M. Grady;Lois L. Myeroff;Sandra E. Swinler;Ashwani Rajput

  • Immunohistochemical Demonstration of Phospho-Akt in High Gleason Grade Prostate Cancer

    Shazli N. Malik;Michael Brattain;Paramita M. Ghosh;Dean A. Troyer

  • Expression of transforming growth factor beta type II receptor leads to reduced malignancy in human breast cancer MCF-7 cells.

    Lu Zhe Sun;Gengfei Wu;James K.V. Willson;Elizabeth Zborowska

  • Demonstration That Mutation of the Type II Transforming Growth Factor β Receptor Inactivates Its Tumor Suppressor Activity in Replication Error-positive Colon Carcinoma Cells

    Jing Wang;LuZhe Sun;Lois Myeroff;Xiaofan Wang

  • Establishment of Mouse Colonic Carcinoma Cell Lines with Different Metastatic Properties

    Michael G. Brattain;Janna Strobel-Stevens;David Fine;Maryla Webb

  • The maximal size of protein to diffuse through the nuclear pore is larger than 60 kDa

    Ruiwen Wang;Michael G. Brattain

  • Heterogeneity of human colon carcinoma

    M. G. Brattain;A. E. Levine;S. Chakrabarty;L. C. Yeoman

  • Comparison of cytotoxicity and DNA breakage activity of congeners of podophyllotoxin including VP16-213 and VM26: a quantitative structure-activity relationship.

    Byron H. Long;Steven T. Musial;Michael G. Brattain

  • Single- and double-strand DNA breakage and repair in human lung adenocarcinoma cells exposed to etoposide and teniposide.

    Byron H. Long;Steven T. Musial;Michael G. Brattain

  • Induction of Survivin Expression by Taxol (Paclitaxel) Is an Early Event, Which Is Independent of Taxol-mediated G2/M Arrest

    Xiang Ling;Ralph J. Bernacki;Michael G. Brattain;Fengzhi Li

  • TGF-beta 1 is an autocrine-negative growth regulator of human colon carcinoma FET cells in vivo as revealed by transfection of an antisense expression vector.

    Shaoping Wu;Dan Theodorescu;Robert S. Kerbel;James K V Willson

  • Antiproliferative Effects of Gastrin Receptor Antagonists and Antibodies to Gastrin on Human Colon Carcinoma Cell Lines

    Naseema M. Hoosein;Peter A. Kiener;Robert C. Curry;Lucio C. Rovati

  • Differential sensitivity of subclasses of human colon carcinoma cell lines to the growth inhibitory effects of transforming growth factor-β1

    Naseema M. Hoosein;Mary K. McKnight;Alan E. Levine;Kathleen M. Mulder

  • Pharmacodynamic Evaluation of the Epidermal Growth Factor Receptor Inhibitor OSI-774 in Human Epidermis of Cancer Patients

    Shazli N. Malik;Lillian L. Siu;Eric K. Rowinsky;Linda DeGraffenried

  • Acetylated Sp3 is a transcriptional activator

    Sudhakar Ammanamanchi;James W. Freeman;Michael G. Brattain

  • Reduced Expression of Transforming Growth Factor β Type I Receptor Contributes to the Malignancy of Human Colon Carcinoma Cells

    Jing Wang;Wei Han;Elizabeth Zborowska;Jiurong Liang

  • Evidence for autocrine growth stimulation of cultured colon tumor cells by a gastrin/cholecystokinin-like peptide

    Naseema M. Hoosein;Peter A. Kiener;Robert C. Curry;Michael G. Brattain

  • Characterization of HCT116 human colon cancer cells in an orthotopic model.

    Ashwani Rajput;Ashwani Rajput;Ivan Dominguez San Martin;Rebecca Rose;Alexander Beko

Frequent Co-Authors

James K V Willson
James K V Willson The University of Texas at Dallas
Sanford D. Markowitz
Sanford D. Markowitz Case Western Reserve University
Robert M. Hoffman
Robert M. Hoffman AntiCancer (United States)
Manuel Hidalgo
Manuel Hidalgo Cornell University
Xiao-Fan Wang
Xiao-Fan Wang Duke University
Harris Busch
Harris Busch Baylor College of Medicine
Bert Vogelstein
Bert Vogelstein Johns Hopkins University
James Varani
James Varani University of Michigan–Ann Arbor
Peter A. Kiener
Peter A. Kiener AstraZeneca (United Kingdom)
Douglas D. Boyd
Douglas D. Boyd The University of Texas MD Anderson Cancer Center

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Best Scientists Citing Michael G. Brattain