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Medicine

D-Index
101
Citations
36930
World Ranking
7995
National Ranking
783

Overview

Janice L. Holton is affiliated with University College London in the United Kingdom. Their research primarily spans the fields of Medicine and Neuroscience, with a significant focus on Neurology, Physiology, Cellular and Molecular Neuroscience, Molecular Biology, and Radiology, Nuclear Medicine and Imaging.

The scientist's work covers a variety of topics related to neurological conditions and treatments, including:

  • Parkinson's Disease Mechanisms and Treatments
  • Alzheimer's disease research and treatments
  • Neurological disorders and treatments
  • Neurological diseases and metabolism
  • Genetic Neurodegenerative Diseases
  • Botulinum Toxin and Related Neurological Disorders
  • Medical Image Segmentation Techniques

Janice L. Holton has contributed to multiple publications over recent years. Some notable papers include:

  • "Genetic determinants of survival in progressive supranuclear palsy: a genome-wide association study" (2020), published in The Lancet Neurology
  • "Prominent astrocytic alpha-synuclein pathology with unique post-translational modification signatures unveiled across Lewy body disorders" (2022), published in Acta Neuropathologica Communications
  • "Demographic, clinical, biomarker, and neuropathological correlates of posterior cortical atrophy: an international cohort study and individual participant data meta-analysis" (2024), published in The Lancet Neurology
  • "Development and validation of an expanded antibody toolset that captures alpha-synuclein pathological diversity in Lewy body diseases" (2023), published in npj Parkinson s Disease
  • "Identification of multiple system atrophy mimicking Parkinson's disease or progressive supranuclear palsy" (2021), published in Brain

The venues where Janice L. Holton has frequently published include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Neuropathology and Applied Neurobiology
  • Acta Neuropathologica Communications
  • npj Parkinson s Disease
  • Brain

The scientist has collaborated extensively with several researchers, among whom frequent co-authors are:

  • Thomas T. Warner
  • Zane Jaunmuktane
  • Yasuo Miki
  • Tammaryn Lashley
  • Tamás Révész

Best Publications

  • Lewy bodies in grafted neurons in subjects with Parkinson's disease suggest host-to-graft disease propagation.

    Jia-Yi Li;Elisabet Englund;Janice L Holton;Denis Soulet

  • A common LRRK2 mutation in idiopathic Parkinson's disease

    William P. Gilks;Patrick M Abou-Sleiman;Sonia Gandhi;Shushant Jain

  • Characteristics of two distinct clinical phenotypes in pathologically proven progressive supranuclear palsy: Richardson's syndrome and PSP-parkinsonism.

    David R Williams;Rohan de Silva;Dominic C Paviour;Alan M Pittman

  • Glucocerebrosidase mutations in clinical and pathologically proven Parkinson's disease

    Juliane Neumann;Jose Bras;Jose Bras;Emma Deas;Sean S. O'Sullivan

  • Lewy- and Alzheimer-type pathologies in Parkinson's disease dementia: which is more important?

    Yaroslau Compta;Laura Parkkinen;Sean S O'Sullivan;Jana Vandrovcova

  • The heritability and genetics of frontotemporal lobar degeneration

    J.D. Rohrer;R. Guerreiro;J. Vandrovcova;J. Uphill

  • A clinico-pathological study of subtypes in Parkinson's disease

    Marianna Selikhova;David R Williams;David R Williams;Peter A Kempster;Peter A Kempster;Janice L Holton

  • The spectrum of pathological involvement of the striatonigral and olivopontocerebellar systems in multiple system atrophy : clinicopathological correlations

    Tetsutaro Ozawa;Dominic Paviour;Dominic Paviour;Niall P. Quinn;Keith A. Josephs

  • Neuropathology underlying clinical variability in patients with synucleinopathies

    Glenda M. Halliday;Janice L. Holton;Tamas Revesz;Dennis W. Dickson

  • α-Synucleinopathy associated with G51D SNCA mutation: a link between Parkinson's disease and multiple system atrophy?

    Aoife P. Kiely;Yasmine T. Asi;Eleanna Kara;Patricia Limousin;Patricia Limousin

  • Relationships between age and late progression of Parkinson’s disease: a clinico-pathological study

    Peter A Kempster;Sean S O'Sullivan;Janice L Holton;Tamas Revesz

  • Clinical outcomes of progressive supranuclear palsy and multiple system atrophy

    Sean S O'Sullivan;Luke A Massey;David R Williams;Laura Silveira-Moriyama

  • Excessive burden of lysosomal storage disorder gene variants in Parkinson's disease

    L.A. Robak;L.A. Robak;I.E. Jansen;I.E. Jansen;J van Rooij;A.G. Uitterlinden

  • Loss of VPS13C Function in Autosomal-Recessive Parkinsonism Causes Mitochondrial Dysfunction and Increases PINK1/Parkin-Dependent Mitophagy.

    Suzanne Lesage;Valérie Drouet;Elisa Majounie;Vincent Deramecourt

  • Does corticobasal degeneration exist? A clinicopathological re-evaluation

    Helen Ling;Sean S O'Sullivan;Janice L Holton;Tamas Revesz

  • Pathological tau burden and distribution distinguishes progressive supranuclear palsy-parkinsonism from Richardson's syndrome.

    David R Williams;Janice L Holton;Catherine Strand;Alan M Pittman

  • PINK1 protein in normal human brain and Parkinson's disease

    S Gandhi;M M K Muqit;L Stanyer;D G Healy

  • Unbiased screen for interactors of leucine-rich repeat kinase 2 supports a common pathway for sporadic and familial Parkinson disease

    A. Beilina;I. N. Rudenko;A. Kaganovich;L. Civiero

  • Research in motion: the enigma of Parkinson's disease pathology spread

    Patrik Brundin;Jia-Yi Li;Janice L. Holton;Olle Lindvall

  • The spectrum of pathological involvement of the striatonigral and olivopontocerebellar systems in multiple system atrophy: Clinicopathological correlations

    T Ozawa;T Revesz;JL Holton;N Quinn

Frequent Co-Authors

Tamas Revesz
Tamas Revesz University College London
Andrew J. Lees
Andrew J. Lees University College London
Henry Houlden
Henry Houlden University College London
Michael G. Hanna
Michael G. Hanna University College London
Nicholas W. Wood
Nicholas W. Wood University College London
John Hardy
John Hardy University College London
Sean S. O'Sullivan
Sean S. O'Sullivan Cork University Hospital
Glenda M. Halliday
Glenda M. Halliday University of Sydney
Kailash P. Bhatia
Kailash P. Bhatia University College London
Lucy R. Wedderburn
Lucy R. Wedderburn University College London

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