D-Index & Metrics Best Publications
Neuroscience
Finland
2023

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Neuroscience D-index 80 Citations 23,578 205 World Ranking 924 National Ranking 9

Research.com Recognitions

Awards & Achievements

2023 - Research.com Neuroscience in Finland Leader Award

2022 - Research.com Neuroscience in Finland Leader Award

Overview

What is he best known for?

The fields of study he is best known for:

  • Internal medicine
  • Neuron
  • Neuroscience

His main research concerns Neuroscience, Cotransporter, GABAergic, Inhibitory postsynaptic potential and Cell biology. His research integrates issues of gamma-Aminobutyric acid, Glutamatergic and Ion channel in his study of Neuroscience. His GABAergic research integrates issues from Epileptogenesis, Epilepsy and Depolarization.

Kai Kaila has researched Depolarization in several fields, including Hippocampal formation, Reversal potential and GABAA receptor. His studies in Inhibitory postsynaptic potential integrate themes in fields like Signal transduction and Postsynaptic potential. The concepts of his Cell biology study are interwoven with issues in Dendritic spine, Endocrinology, Glycine receptor and Internal medicine.

His most cited work include:

  • The K+/Cl- co-transporter KCC2 renders GABA hyperpolarizing during neuronal maturation. (1734 citations)
  • Cation–chloride co-transporters in neuronal communication, development and trauma (694 citations)
  • Cation-chloride cotransporters and neuronal function. (597 citations)

What are the main themes of his work throughout his whole career to date?

The scientist’s investigation covers issues in Neuroscience, Biophysics, GABAA receptor, Biochemistry and Hippocampal formation. His research ties Postsynaptic potential and Neuroscience together. His research in Biophysics intersects with topics in Extracellular, Intracellular pH and Intracellular.

His GABAA receptor research includes elements of Agonist, Pharmacology, Neurotransmission and Cell biology. In his research, Bursting is intimately related to Giant depolarizing potentials, which falls under the overarching field of Hippocampal formation. His biological study spans a wide range of topics, including Cotransporter and Glutamatergic.

He most often published in these fields:

  • Neuroscience (42.42%)
  • Biophysics (25.11%)
  • GABAA receptor (19.48%)

What were the highlights of his more recent work (between 2016-2021)?

  • Asphyxia (6.93%)
  • Internal medicine (14.72%)
  • Endocrinology (13.85%)

In recent papers he was focusing on the following fields of study:

Kai Kaila mainly investigates Asphyxia, Internal medicine, Endocrinology, Anesthesia and Bumetanide. His work on Hippocampal formation as part of general Internal medicine research is frequently linked to Neurodegeneration, bridging the gap between disciplines. When carried out as part of a general Endocrinology research project, his work on Vasopressin, GABAergic and Copeptin is frequently linked to work in Fetus, therefore connecting diverse disciplines of study.

His studies deal with areas such as Phenobarbital, Pharmacology, Giant depolarizing potentials and Epilepsy as well as Bumetanide. His Cotransporter research integrates issues from Depolarization and Embryo. His Neuroscience course of study focuses on Ionotropic effect and GABAA receptor.

Between 2016 and 2021, his most popular works were:

  • Simultaneous two-photon imaging of intracellular chloride concentration and pH in mouse pyramidal neurons in vivo (56 citations)
  • Vasopressin excites interneurons to suppress hippocampal network activity across a broad span of brain maturity at birth. (30 citations)
  • Bumepamine, a brain-permeant benzylamine derivative of bumetanide, does not inhibit NKCC1 but is more potent to enhance phenobarbital's anti-seizure efficacy. (18 citations)

In his most recent research, the most cited papers focused on:

  • Internal medicine
  • Neuron
  • Enzyme

Kai Kaila focuses on Internal medicine, Endocrinology, Asphyxia, Hippocampal formation and Giant depolarizing potentials. His work on Cotransporter expands to the thematically related Internal medicine. The various areas that Kai Kaila examines in his Asphyxia study include Copeptin and Hypoxia, Hypercapnia.

His Hippocampal formation research also works with subjects such as

  • Bumetanide which is related to area like Pharmacology, Embryo, Depolarization and GABAergic,
  • Oxytocin and related GABAA receptor. His GABAA receptor research includes themes of Gephyrin, Collybistin and Neurogenesis, Cell biology, Neuron maturation. His Giant depolarizing potentials research is multidisciplinary, incorporating perspectives in Neuroscience, Epilepsy, Postsynaptic potential and Precocial.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

The K+/Cl- co-transporter KCC2 renders GABA hyperpolarizing during neuronal maturation.

Claudio Rivera;Juha Voipio;John A. Payne;Eva Ruusuvuori.
Nature (1999)

2240 Citations

Cation–chloride co-transporters in neuronal communication, development and trauma

John A Payne;Claudio Rivera;Juha Voipio;Kai Kaila.
Trends in Neurosciences (2003)

896 Citations

Cation-chloride cotransporters and neuronal function.

Peter Blaesse;Matti S. Airaksinen;Claudio Rivera;Kai Kaila.
Neuron (2009)

769 Citations

Ionic basis of GABAA receptor channel function in the nervous system

Kai Kaila.
Progress in Neurobiology (1994)

751 Citations

Phase Synchrony among Neuronal Oscillations in the Human Cortex

J. Matias Palva;Satu Palva;Kai Kaila.
The Journal of Neuroscience (2005)

712 Citations

Modulation of pH by neuronal activity

M. Chesler;K. Kaila.
Trends in Neurosciences (1992)

645 Citations

Perturbed Chloride Homeostasis and GABAergic Signaling in Human Temporal Lobe Epilepsy

Gilles Huberfeld;Lucia Wittner;Stéphane Clemenceau;Michel Baulac.
The Journal of Neuroscience (2007)

602 Citations

BDNF-induced TrkB activation down-regulates the K+–Cl− cotransporter KCC2 and impairs neuronal Cl− extrusion

Claudio Rivera;Hong Li;Judith Thomas-Crusells;Hannele Lahtinen.
Journal of Cell Biology (2002)

571 Citations

Cation-chloride cotransporters in neuronal development, plasticity and disease

Kai Kaila;Theodore J. Price;John A. Payne;Martin Puskarjov.
Nature Reviews Neuroscience (2014)

553 Citations

Mechanism of Activity-Dependent Downregulation of the Neuron-Specific K-Cl Cotransporter KCC2

Claudio Rivera;Juha Voipio;Judith Thomas-Crusells;Hong Li.
The Journal of Neuroscience (2004)

542 Citations

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