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Immunology

D-Index
85
Citations
47230
World Ranking
1293
National Ranking
673

Overview

Huan Yang is affiliated with the Feinstein Institute for Medical Research in the United States, focusing on fields related to medicine and biochemistry, genetics, and molecular biology. Their research covers a range of subfields including molecular biology, immunology, infectious diseases, neurology, and clinical biochemistry.

Their scientific contributions include work on topics such as advanced glycation end products research, vagus nerve stimulation research, COVID-19 clinical research studies, SARS-CoV-2 and COVID-19 research, reproductive system and pregnancy, immune response and inflammation, and neutrophil, myeloperoxidase, and oxidative mechanisms.

The frequent venues for Huan Yang's publications include:

  • Molecular Medicine
  • Frontiers in Immunology
  • Research Square (Research Square)
  • The FASEB Journal
  • Proceedings of the National Academy of Sciences

Notable recent papers by Huan Yang include:

  • Targeting Inflammation Driven by HMGB1, 2020, Frontiers in Immunology
  • HMGB1 released from nociceptors mediates inflammation, 2021, Proceedings of the National Academy of Sciences

Frequent co-authors collaborating with Huan Yang are:

  • Kevin J. Tracey
  • Jan Andersson
  • Sangeeta S. Chavan
  • Sam J. George
  • Eric H. Chang

The research produced by Huan Yang displays an interdisciplinary approach, intersecting immunological mechanisms and molecular biology with clinical biochemistry and neurology. The focus on inflammation-related pathways and infection, especially in the context of COVID-19 and related immune responses, is evident across their publications.

Best Publications

  • Vagus nerve stimulation attenuates the systemic inflammatory response to endotoxin

    Lyudmila V. Borovikova;Svetlana Ivanova;Minghuang Zhang;Huan Yang

  • HMG-1 as a Late Mediator of Endotoxin Lethality in Mice

    Haichao Wang;Ona Bloom;Minghuang Zhang;Jaideep M. Vishnubhakat

  • Nicotinic acetylcholine receptor alpha7 subunit is an essential regulator of inflammation.

    Hong Wang;Man Yu;Mahendar Ochani;Carol Ann Amella

  • High mobility group 1 protein (HMG-1) stimulates proinflammatory cytokine synthesis in human monocytes.

    Ulf Andersson;Haichao Wang;Karin Palmblad;Ann-Charlotte Aveberger

  • Reversing established sepsis with antagonists of endogenous high-mobility group box 1

    Huan Yang;Mahendar Ochani;Jianhua Li;Xiaoling Qiang

  • The nuclear factor HMGB1 mediates hepatic injury after murine liver ischemia-reperfusion

    Allan Tsung;Rohit Sahai;Hiroyuki Tanaka;Atsunori Nakao

  • HMGB1 signals through toll-like receptor (TLR) 4 and TLR2.

    Man Yu;Haichao Wang;Aihao Ding;Douglas T Golenbock

  • A critical cysteine is required for HMGB1 binding to Toll-like receptor 4 and activation of macrophage cytokine release

    Huan Yang;Hulda S. Hreggvidsdottir;Karin Palmblad;Haichao Wang

  • Novel role of PKR in inflammasome activation and HMGB1 release

    Ben Lu;Takahisa Nakamura;Karen Inouye;Jianhua Li

  • Mutually exclusive redox forms of HMGB1 promote cell recruitment or proinflammatory cytokine release

    Emilie Venereau;Maura Casalgrandi;Milena Schiraldi;Daniel J. Antoine

  • Ethyl pyruvate prevents lethality in mice with established lethal sepsis and systemic inflammation

    Luis Ulloa;Mahendar Ochani;Huan Yang;Mahira Tanovic

  • The cytokine activity of HMGB1.

    Huan Yang;Haichao Wang;Christopher J. Czura;Kevin J. Tracey

  • Pharmacological Stimulation of the Cholinergic Antiinflammatory Pathway

    Thomas R. Bernik;Steven G. Friedman;Mahendar Ochani;Robert DiRaimo

  • Targeting Inflammation Driven by HMGB1.

    Huan Yang;Haichao Wang;Ulf Andersson

  • Extracellular role of HMGB1 in inflammation and sepsis

    H. Wang;H. Yang;K. J. Tracey

  • HMGB1 as a late mediator of lethal systemic inflammation.

    Haichao Wang;Huan Yang;Christopher J. Czura;Andrew E. Sama

  • High Mobility Group Box Protein 1: An Endogenous Signal for Dendritic Cell Maturation and Th1 Polarization

    Davorka Messmer;Huan Yang;Huan Yang;Gloria Telusma;Faye Knoll

  • Activation of gene expression in human neutrophils by high mobility group box 1 protein

    Jong Sung Park;John Arcaroli;Ho Kee Yum;Huan Yang

  • The Endotoxin Delivery Protein HMGB1 Mediates Caspase-11-Dependent Lethality in Sepsis

    Meihong Deng;Yiting Tang;Wenbo Li;Xiangyu Wang

  • Structural basis for the proinflammatory cytokine activity of high mobility group box 1.

    Jianhua Li;Riikka Kokkola;Siamak Tabibzadeh;Runkuan Yang

  • Successful treatment of collagen-induced arthritis in mice and rats by targeting extracellular high mobility group box chromosomal protein 1 activity

    R. Kokkola;J. Li;E. Sundberg;A.-C. Aveberger

  • The many faces of HMGB1: molecular structure-functional activity in inflammation, apoptosis, and chemotaxis

    Huan Yang;Daniel J. Antoine;Ulf Andersson;Kevin J. Tracey

Frequent Co-Authors

Kevin J. Tracey
Kevin J. Tracey Feinstein Institute for Medical Research
Haichao Wang
Haichao Wang Feinstein Institute for Medical Research
Jianhua Li
Jianhua Li Feinstein Institute for Medical Research
Ulf Andersson
Ulf Andersson Karolinska University Hospital
Sangeeta S. Chavan
Sangeeta S. Chavan Feinstein Institute for Medical Research
Ping Wang
Ping Wang Feinstein Institute for Medical Research
Luis Ulloa
Luis Ulloa Duke University
Timothy R. Billiar
Timothy R. Billiar University of Pittsburgh
Helena Erlandsson Harris
Helena Erlandsson Harris Karolinska Institute
Mitchell P. Fink
Mitchell P. Fink University of California, Los Angeles

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