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Jonathan W. Stewart

Jonathan W. Stewart

D-Index & Metrics

Medicine

D-Index
80
Citations
29971
World Ranking
16945
National Ranking
8498

Overview

Jonathan W. Stewart is affiliated with Columbia University in the United States. Their research spans multiple disciplines, primarily focused on neuroscience, medicine, and psychology. Within these areas, Stewart has contributed substantially to subfields including experimental and cognitive psychology, pharmacology, cognitive neuroscience, endocrine and autonomic systems, and radiology, nuclear medicine, and imaging.

Their recent published work addresses diverse aspects of mental health and treatment of major depression. Notable papers include:

  • A randomized, controlled trial assessing the acute efficacy of triple chronotherapy in unipolar depression (2020, Journal of Affective Disorders)
  • Gray matter reorganization underpinnings of antidepressant treatment of persistent depressive disorder (2021, European Neuropsychopharmacology)
  • Serotonin-norepinephrine reuptake inhibitor antidepressant effects on regional connectivity of the thalamus in persistent depressive disorder: evidence from two randomized, double-blind, placebo-controlled clinical trials (2022, Brain Communications)
  • Personalized symptom clusters that predict depression treatment outcomes: A replication of machine learning methods (2023, Journal of Affective Disorders Reports)
  • Effect of age on the response to serotonergic and noradrenergic antidepressants: A systematic review, meta-regression and individual participant data pooled analysis (2025, Journal of Psychiatric Research)

Stewart's frequent co-authors include David J. Hellerstein, Jie Yang, Ying Chen, Patrick J. McGrath, and Bradley S. Peterson. Collaboration with these researchers indicates an interdisciplinary approach to mental health and neuropharmacology.

Their publications appear repeatedly in journals such as the Journal of Psychiatric Research, Journal of Affective Disorders, European Neuropsychopharmacology, Brain Communications, and the Journal of Affective Disorders Reports. This consistency in publication venues reflects a focus on psychiatric research and neuropsychopharmacology.

Stewart's main research topics cover:

  • Mental Health Research Topics
  • Treatment of Major Depression
  • Functional Brain Connectivity Studies
  • Circadian Rhythm and Melatonin
  • Advanced Neuroimaging Techniques and Applications
  • Tryptophan and Brain Disorders
  • Stress Responses and Cortisol

Their work often integrates neuroimaging and pharmacological approaches to investigate brain connectivity and treatment effects in depressive disorders. This includes detailed examination of serotonergic and noradrenergic antidepressants and their influence on brain function and structure, as well as machine learning methods applied to symptom pattern predictions for depression treatment outcomes.

Overall, Jonathan W. Stewart's research contributes to understanding the neurobiological and psychological facets of depression, using multidisciplinary tools from cognitive neuroscience, pharmacology, and advanced imaging techniques.

Best Publications

  • Acute and Longer- Term Outcomes in Depressed Outpatients Requiring One or Several Treatment Steps: A STAR*D Report

    A. John Rush;Madhukar H. Trivedi;Stephen R. Wisniewski;Andrew A. Nierenberg

  • Bupropion-SR, sertraline, or venlafaxine-XR after failure of SSRIs for depression.

    A. John Rush;Madhukar H. Trivedi;Stephen R. Wisniewski;Jonathan W. Stewart

  • Sequenced treatment alternatives to relieve depression (STAR * D): rationale and design

    A.John Rush;Maurizio Fava;Stephen R Wisniewski;Philip W Lavori

  • Effect of Age at Onset on the Course of Major Depressive Disorder

    Sidney Zisook;Ira Lesser;Jonathan W. Stewart;Stephen R. Wisniewski

  • Light therapy for seasonal affective disorder. A review of efficacy.

    M Terman;J S Terman;F M Quitkin;P J McGrath

  • Anti-interleukin-31 receptor a antibody for atopic dermatitis

    Thomas Ruzicka;Jon M. Hanifin;Masutaka Furue;Grazyna Pulka

  • Combining Medications to Enhance Depression Outcomes (CO-MED): Acute and Long-Term Outcomes of a Single-Blind Randomized Study

    A. John Rush;Madhukar H. Trivedi;Jonathan W. Stewart;Andrew A. Nierenberg

  • Antidepressant Specificity in Atypical Depression

    Michael R. Liebowitz;Frederic M. Quitkin;Jonathan W. Stewart;Patrick J. McGrath

  • Tranylcypromine Versus Venlafaxine Plus Mirtazapine Following Three Failed Antidepressant Medication Trials for Depression: A STAR*D Report

    Patrick J. McGrath;Jonathan W. Stewart;Maurizio Fava;Madhukar H Trivedi

  • Divalproex treatment for youth with explosive temper and mood lability: a double-blind, placebo-controlled crossover design.

    Stephen J. Donovan;Jonathan W. Stewart;Edward V. Nunes;Frederic M. Quitkin

  • Phenelzine v Imipramine in Atypical Depression: A Preliminary Report

    Michael R. Liebowitz;Frederic M. Quitkin;Jonathan W. Stewart;Patrick J. McGrath

  • Electroencephalographic Alpha Measures Predict Therapeutic Response to a Selective Serotonin Reuptake Inhibitor Antidepressant: Pre- and Post-Treatment Findings

    Gerard E. Bruder;James P. Sedoruk;Jonathan W. Stewart;Patrick J. McGrath

  • Depression With Atypical Features in the National Comorbidity Survey Classification, Description, and Consequences

    Louis S. Matza;Dennis A. Revicki;Jonathan R. Davidson;Jonathan W. Stewart

  • Identification of True Drug Response to Antidepressants: Use of Pattern Analysis

    Frederic M. Quitkin;Judith G. Rabkin;Donald Ross;Jonathan W. Stewart

  • Imipramine treatment of alcoholics with primary depression: A placebo-controlled clinical trial.

    Patrick J. McGrath;Edward V. Nunes;Jonathan W. Stewart;Deberah Goldman

  • Antidepressants Normalize the Default Mode Network in Patients With Dysthymia

    Jonathan Posner;David J. Hellerstein;Inbal Gat;Anna Mechling

  • Residual Symptoms in Depressed Outpatients Who Respond by 50% But Do Not Remit to Antidepressant Medication

    Shawn M. McClintock;Mustafa M. Husain;Stephen R. Wisniewski;Andrew A. Nierenberg

  • Use of Pattern Analysis to Identify True Drug Response: A Replication

    Frederic M. Quitkin;Judith D. Rabkin;Jefferey M. Markowitz;Jonathan W. Stewart

  • Effects of antidepressant medication on sexual function: a controlled study.

    Wilma M. Harrison;Judith G. Rabkin;Anke A. Ehrhardt;Jonathan W. Stewart

  • Phenelzine versus imipramine in the treatment of probable atypical depression: defining syndrome boundaries of selective MAOI responders

    Frederic M. Quitkin;Jonathan W. Stewart;Patrick J. McGrath;Michael R. Liebowitz

Frequent Co-Authors

Patrick J. McGrath
Patrick J. McGrath Columbia University
Frederic M. Quitkin
Frederic M. Quitkin Columbia University
Donald F. Klein
Donald F. Klein New York University
Gerard E. Bruder
Gerard E. Bruder Columbia University
Judith G. Rabkin
Judith G. Rabkin Columbia University
Maurizio Fava
Maurizio Fava Harvard University
Edward V. Nunes
Edward V. Nunes Columbia University
Michael R. Liebowitz
Michael R. Liebowitz Columbia University
Stephen R. Wisniewski
Stephen R. Wisniewski University of Pittsburgh
Madhukar H. Trivedi
Madhukar H. Trivedi The University of Texas Southwestern Medical Center

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