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Toshiyuki Shimizu

Toshiyuki Shimizu

University of Tokyo
Japan

D-Index & Metrics

Biology and Biochemistry

D-Index
68
Citations
15042
World Ranking
7872
National Ranking
531

Toshiyuki Shimizu publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Toshiyuki Shimizu sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 280 publications — 74th percentile

74% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Toshiyuki Shimizu D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Toshiyuki Shimizu sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 68 D-Index — 61st percentile

61% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

Toshiyuki Shimizu is a researcher affiliated with the University of Tokyo in Japan. Their work spans multiple disciplines within the life sciences, primarily focusing on biochemistry, genetics, and molecular biology, with significant contributions also in medicine and immunology and microbiology.

The researcher has engaged extensively in areas such as molecular biology, immunology, epidemiology, oncology, and cancer research. Key topics in their research include immune response and inflammation, RNA and protein synthesis mechanisms, interferon and immune responses, antimicrobial peptides and activities, inflammasome and immune disorders, NF-κB signaling pathways, and ubiquitin and proteasome pathways.

Their recent scientific publications include:

  • Structural Diversity of Ubiquitin E3 Ligase, 2021, Molecules
  • Structure of SARS-CoV-2 membrane protein essential for virus assembly, 2022, Nature Communications
  • Structural basis for the oligomerization-mediated regulation of NLRP3 inflammasome activation, 2022, Proceedings of the National Academy of Sciences
  • Structure of the bile acid transporter and HBV receptor NTCP, 2022, Nature
  • Structural and functional understanding of the toll-like receptors, 2021, Protein Science

Frequent co-authors collaborating with Toshiyuki Shimizu include:

  • Umeharu Ohto
  • Zhikuan Zhang
  • Kensuke Miyake
  • Kentaro Sakaniwa
  • Sachiko Toma-Fukai

Their research appears in multiple publication venues frequently, including:

  • Nature Communications
  • Brain Stimulation
  • Nature
  • FEBS Letters
  • Nature Structural & Molecular Biology

Best Publications

  • Structural basis of the membrane-targeting and unmasking mechanisms of the radixin FERM domain.

    Keisuke Hamada;Toshiyuki Shimizu;Takeshi Matsui;Shoichiro Tsukita

  • Epigenetic Control of rDNA Loci in Response to Intracellular Energy Status

    Akiko Murayama;Kazuji Ohmori;Akiko Fujimura;Hiroshi Minami

  • Structural basis for Ca(2+)-induced activation of human PAD4

    Kyouhei Arita;Hiroshi Hashimoto;Toshiyuki Shimizu;Katsuhiko Nakashima

  • Structural basis of species-specific endotoxin sensing by innate immune receptor TLR4/MD-2

    Umeharu Ohto;Koichi Fukase;Kensuke Miyake;Toshiyuki Shimizu

  • Structural Analysis Reveals that Toll-like Receptor 7 Is a Dual Receptor for Guanosine and Single-Stranded RNA.

    Zhikuan Zhang;Umeharu Ohto;Takuma Shibata;Elena Krayukhina

  • Structural reorganization of the Toll-like receptor 8 dimer induced by agonistic ligands

    Hiromi Tanji;Umeharu Ohto;Takuma Shibata;Kensuke Miyake

  • Toll-like receptor 8 senses degradation products of single-stranded RNA.

    Hiromi Tanji;Umeharu Ohto;Takuma Shibata;Masato Taoka

  • Structural basis of CpG and inhibitory DNA recognition by Toll-like receptor 9

    Umeharu Ohto;Takuma Shibata;Hiromi Tanji;Hanako Ishida

  • Crystal structure of human RhoA in a dominantly active form complexed with a GTP analogue.

    Kentaro Ihara;Sachiko Muraguchi;Masato Kato;Toshiyuki Shimizu

  • Crystal structure of an IRF-DNA complex reveals novel DNA recognition and cooperative binding to a tandem repeat of core sequences.

    Yoshifumi Fujii;Toshiyuki Shimizu;Masahiro Kusumoto;Yoshimasa Kyogoku

  • Crystal structure of PHO4 bHLH domain-DNA complex: flanking base recognition.

    Toshiyuki Shimizu;Atsuki Toumoto;Kentaro Ihara;Masato Shimizu

  • Structural basis for the diversity of DNA recognition by bZIP transcription factors.

    Yoshifumi Fujii;Toshiyuki Shimizu;Takashi Toda;Mitsuhiro Yanagida

  • A Pentatricopeptide Repeat Protein Is a Site Recognition Factor in Chloroplast RNA Editing

    Kenji Okuda;Takahiro Nakamura;Mamoru Sugita;Toshiyuki Shimizu

  • Novel potent orally active selective VEGFR-2 tyrosine kinase inhibitors: synthesis, structure-activity relationships, and antitumor activities of N-phenyl-N'-{4-(4-quinolyloxy)phenyl}ureas.

    Kazuo Kubo;Toshiyuki Shimizu;Shin-ichi Ohyama;Hideko Murooka

  • Structural basis of adhesion-molecule recognition by ERM proteins revealed by the crystal structure of the radixin-ICAM-2 complex

    Keisuke Hamada;Toshiyuki Shimizu;Toshiyuki Shimizu;Shigenobu Yonemura;Shoichiro Tsukita

  • Quinoline derivatives and quinazoline derivatives inhibiting autophosphorylation of growth factor receptor originating in platelet and pharmaceutical compositions containing the same

    Shinichiro Iyaku Tansaku Kenkyusho Kato;Yoshiko Iyaku Tansaku Kenkyusho Kobayashi;Kazuo Iyaku Tansaku Kenkyusho Kubo;Hideko Iyaku Tansaku Kenkyusho Murooka

  • INSIGHTS INTO MULTISTEP PHOSPHORELAY FROM THE CRYSTAL STRUCTURE OF THE C-TERMINAL HPT DOMAIN OF ARCB

    Masato Kato;Takeshi Mizuno;Toshiyuki Shimizu;Toshio Hakoshima

  • The structural basis of Rho effector recognition revealed by the crystal structure of human RhoA complexed with the effector domain of PKN/PRK1.

    Ryoko Maesaki;Kentaro Ihara;Toshiyuki Shimizu;Shinya Kuroda;Shinya Kuroda

  • Structural Basis for Novel Interactions between Human Translesion Synthesis Polymerases and Proliferating Cell Nuclear Antigen

    Asami Hishiki;Hiroshi Hashimoto;Tomo Hanafusa;Keijiro Kamei

  • Architectures of class-defining and specific domains of glutamyl-tRNA synthetase

    Osamu Nureki;Dmitry G. Vassylyev;Katsuo Katayanagi;Toshiyuki Shimizu

Frequent Co-Authors

Toshio Hakoshima
Toshio Hakoshima Nara Institute of Science and Technology
Kensuke Miyake
Kensuke Miyake Tokyo University of Science
Hiroshi Iwasaki
Hiroshi Iwasaki Tokyo Institute of Technology
Takeshi Mizuno
Takeshi Mizuno Nagoya University
Shoichiro Tsukita
Shoichiro Tsukita Kyoto University
Hang Yin
Hang Yin Tsinghua University
Susumu Uchiyama
Susumu Uchiyama Osaka University
Shinya Kuroda
Shinya Kuroda University of Tokyo
Akiyoshi Fukamizu
Akiyoshi Fukamizu University of Tsukuba
Hisashi Hirano
Hisashi Hirano Yokohama City University

External Links

Personal website of Toshiyuki Shimizu

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Best Scientists Citing Toshiyuki Shimizu

Toshio Hakoshima

Toshio Hakoshima

Nara Institute of Science and Technology

Publications: 37

Ian Small

Ian Small

University of Western Australia

Publications: 24

Roman Jerala

Roman Jerala

National Institute of Chemistry

Publications: 22

Toshiharu Shikanai

Toshiharu Shikanai

Kyoto University

Publications: 20

Jijie Chai

Jijie Chai

Westlake University

Publications: 16

Eleftherios P. Diamandis

Eleftherios P. Diamandis

Mount Sinai Hospital

Publications: 16

Ralf Erdmann

Ralf Erdmann

Ruhr University Bochum

Publications: 15

Shigeyuki Yokoyama

Shigeyuki Yokoyama

RIKEN

Publications: 15

Jörg Kudla

Jörg Kudla

University of Münster

Publications: 15

Eicke Latz

Eicke Latz

German Rheumatism Research Centre

Publications: 15

Anne J. Ridley

Anne J. Ridley

University of Bristol

Publications: 15

Kensuke Miyake

Kensuke Miyake

Tokyo University of Science

Publications: 15

Osamu Nureki

Osamu Nureki

University of Tokyo

Publications: 15

Klaus Aktories

Klaus Aktories

University of Freiburg

Publications: 14

Takeshi Mizuno

Takeshi Mizuno

Nagoya University

Publications: 13

Alfred Wittinghofer

Alfred Wittinghofer

Max Planck Society

Publications: 13

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