Toshiyuki Shimizu

Overview

Best Publications

• Structural basis of the membrane-targeting and unmasking mechanisms of the radixin FERM domain.

  Keisuke Hamada;Toshiyuki Shimizu;Takeshi Matsui;Shoichiro Tsukita

  478
  Citations

• Epigenetic Control of rDNA Loci in Response to Intracellular Energy Status

  Akiko Murayama;Kazuji Ohmori;Akiko Fujimura;Hiroshi Minami

  444
  Citations

• Structural basis for Ca(2+)-induced activation of human PAD4

  Kyouhei Arita;Hiroshi Hashimoto;Toshiyuki Shimizu;Katsuhiko Nakashima

  431
  Citations

• Structural basis of species-specific endotoxin sensing by innate immune receptor TLR4/MD-2

  Umeharu Ohto;Koichi Fukase;Kensuke Miyake;Toshiyuki Shimizu

  412
  Citations

• Structural Analysis Reveals that Toll-like Receptor 7 Is a Dual Receptor for Guanosine and Single-Stranded RNA.

  Zhikuan Zhang;Umeharu Ohto;Takuma Shibata;Elena Krayukhina

  403
  Citations

• Structural reorganization of the Toll-like receptor 8 dimer induced by agonistic ligands

  Hiromi Tanji;Umeharu Ohto;Takuma Shibata;Kensuke Miyake

  398
  Citations

• Toll-like receptor 8 senses degradation products of single-stranded RNA.

  Hiromi Tanji;Umeharu Ohto;Takuma Shibata;Masato Taoka

  378
  Citations

• Structural basis of CpG and inhibitory DNA recognition by Toll-like receptor 9

  Umeharu Ohto;Takuma Shibata;Hiromi Tanji;Hanako Ishida

  370
  Citations

• Crystal structure of human RhoA in a dominantly active form complexed with a GTP analogue.

  Kentaro Ihara;Sachiko Muraguchi;Masato Kato;Toshiyuki Shimizu

  319
  Citations

• Crystal structure of an IRF-DNA complex reveals novel DNA recognition and cooperative binding to a tandem repeat of core sequences.

  Yoshifumi Fujii;Toshiyuki Shimizu;Masahiro Kusumoto;Yoshimasa Kyogoku

  307
  Citations

• Crystal structure of PHO4 bHLH domain-DNA complex: flanking base recognition.

  Toshiyuki Shimizu;Atsuki Toumoto;Kentaro Ihara;Masato Shimizu

  291
  Citations

• Structural basis for the diversity of DNA recognition by bZIP transcription factors.

  Yoshifumi Fujii;Toshiyuki Shimizu;Takashi Toda;Mitsuhiro Yanagida

  247
  Citations

• A Pentatricopeptide Repeat Protein Is a Site Recognition Factor in Chloroplast RNA Editing

  Kenji Okuda;Takahiro Nakamura;Mamoru Sugita;Toshiyuki Shimizu

  234
  Citations

• Novel potent orally active selective VEGFR-2 tyrosine kinase inhibitors: synthesis, structure-activity relationships, and antitumor activities of N-phenyl-N'-{4-(4-quinolyloxy)phenyl}ureas.

  Kazuo Kubo;Toshiyuki Shimizu;Shin-ichi Ohyama;Hideko Murooka

  233
  Citations

• Structural basis of adhesion-molecule recognition by ERM proteins revealed by the crystal structure of the radixin-ICAM-2 complex

  Keisuke Hamada;Toshiyuki Shimizu;Toshiyuki Shimizu;Shigenobu Yonemura;Shoichiro Tsukita

  232
  Citations

• Quinoline derivatives and quinazoline derivatives inhibiting autophosphorylation of growth factor receptor originating in platelet and pharmaceutical compositions containing the same

  Shinichiro Iyaku Tansaku Kenkyusho Kato;Yoshiko Iyaku Tansaku Kenkyusho Kobayashi;Kazuo Iyaku Tansaku Kenkyusho Kubo;Hideko Iyaku Tansaku Kenkyusho Murooka

  222
  Citations

• INSIGHTS INTO MULTISTEP PHOSPHORELAY FROM THE CRYSTAL STRUCTURE OF THE C-TERMINAL HPT DOMAIN OF ARCB

  Masato Kato;Takeshi Mizuno;Toshiyuki Shimizu;Toshio Hakoshima

  219
  Citations

• The structural basis of Rho effector recognition revealed by the crystal structure of human RhoA complexed with the effector domain of PKN/PRK1.

  Ryoko Maesaki;Kentaro Ihara;Toshiyuki Shimizu;Shinya Kuroda;Shinya Kuroda

  204
  Citations

• Structural Basis for Novel Interactions between Human Translesion Synthesis Polymerases and Proliferating Cell Nuclear Antigen

  Asami Hishiki;Hiroshi Hashimoto;Tomo Hanafusa;Keijiro Kamei

  203
  Citations

• Architectures of class-defining and specific domains of glutamyl-tRNA synthetase

  Osamu Nureki;Dmitry G. Vassylyev;Katsuo Katayanagi;Toshiyuki Shimizu

  192
  Citations