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Chemistry

D-Index
45
Citations
7631
World Ranking
16420
National Ranking
4091

Biology and Biochemistry

D-Index
51
Citations
9335
World Ranking
17172
National Ranking
7071

Overview

Brian Bothner is affiliated with Montana State University in the United States. Their research contributions span multiple areas within biochemistry, genetics, and molecular biology, with significant focus on molecular biology and related subfields.

Their main fields of study include:

  • Biochemistry, Genetics and Molecular Biology
  • Medicine

Within these broad areas, subfields of interest include:

  • Molecular Biology
  • Renewable Energy, Sustainability and the Environment
  • Ecology
  • Health, Toxicology and Mutagenesis
  • Genetics

Bothner's research covers key topics such as:

  • Metabolomics and Mass Spectrometry Studies
  • DNA Repair Mechanisms
  • Metalloenzymes and iron-sulfur proteins
  • Microbial Community Ecology and Physiology
  • Arsenic contamination and mitigation
  • Osteoarthritis Treatment and Mechanisms
  • Photosynthetic Processes and Mechanisms

Frequent publication venues for Bothner's work include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Biological Chemistry
  • Nature Communications
  • International Journal of Molecular Sciences
  • Nucleic Acids Research

Some of the recent papers authored or co-authored by Bothner are:

  • "Aerobic bacterial methane synthesis," 2021, Proceedings of the National Academy of Sciences
  • "Adeno-Associated Virus (AAV) Capsid Stability and Liposome Remodeling During Endo/Lysosomal pH Trafficking," 2020, Viruses
  • "Biochemical and structural characterization of an aromatic ring-hydroxylating dioxygenase for terephthalic acid catabolism," 2022, Proceedings of the National Academy of Sciences
  • "Introducing the ArsR-Regulated Arsenic Stimulon," 2021, Frontiers in Microbiology
  • "Hydrogen-deuterium exchange reveals a dynamic DNA-binding map of replication protein A," 2020, Nucleic Acids Research

Bothner has collaborated frequently with a set of co-authors, including:

  • Monika Tokmina-Lukaszewska
  • Edwin Antony
  • Angela Patterson
  • Jenna R. Mattice
  • Jaigeeth Deveryshetty

Best Publications

  • Carbohydrate structure of erythropoietin expressed in Chinese hamster ovary cells by a human erythropoietin cDNA.

    H Sasaki;B Bothner;A Dell;M Fukuda

  • Cooperative signals governing ARF-mdm2 interaction and nucleolar localization of the complex.

    Jason D. Weber;Mei-Ling Kuo;Brian Bothner;Brian Bothner;Enrico L. DiGiammarino

  • A novel mechanism of tumorigenesis involving pH-dependent destabilization of a mutant p53 tetramer

    Enrico L DiGiammarino;Amanda S Lee;Craig Cadwell;Weixing Zhang

  • Antiviral agent blocks breathing of the common cold virus.

    J. Kathleen Lewis;Brian Bothner;Thomas J. Smith;Gary Siuzdak

  • Mass spectrometry and viral analysis

    Gary Siuzdak;Brian Bothner;Mark Yeager;Christophe Brugidou

  • Structure and Dynamics of Adeno-Associated Virus Serotype 1 VP1-Unique N-Terminal Domain and Its Role in Capsid Trafficking

    Balasubramanian Venkatakrishnan;Joseph Yarbrough;John Domsic;Antonette Bennett

  • Evidence of viral capsid dynamics using limited proteolysis and mass spectrometry.

    Brian Bothner;X. Fan Dong;Lisa Bibbs;John E. Johnson

  • New Technologies for Studying Biofilms.

    Michael J. Franklin;Connie B. Chang;Tatsuya Akiyama;Brian Bothner

  • Mass Spectrometry of an Intact Virus

    Stephen D. Fuerstenau;W. Henry Benner;John J. Thomas;Christophe Brugidou

  • Comparative Analysis of Adeno-Associated Virus Capsid Stability and Dynamics

    Vamseedhar Rayaprolu;Shannon Kruse;Ravi Kant;Balasubramanian Venkatakrishnan

  • Thermal Stability as a Determinant of AAV Serotype Identity.

    Antonette Bennett;Saajan Patel;Mario Mietzsch;Ariana Jose

  • Demonstration of Protein-Based Human Identification Using the Hair Shaft Proteome

    Glendon J. Parker;Tami Leppert;Deon S. Anex;Jonathan K. Hilmer

  • Defining the molecular basis of Arf and Hdm2 interactions.

    Brian Bothner;William S Lewis;Enrico L DiGiammarino;Jason D Weber

  • [FeFe]-Hydrogenase Oxygen Inactivation Is Initiated at the H Cluster 2Fe Subcluster

    Kevin D. Swanson;Michael W. Ratzloff;David W. Mulder;Jacob H. Artz

  • Structural and Functional Studies of Archaeal Viruses

    C. Martin Lawrence;Smita Menon;Brian J. Eilers;Brian Bothner

  • Monitoring enzyme catalysis with mass spectrometry.

    Brian Bothner;Rodrigo Chavez;Jing Wei;Christian Strupp

  • Mechanistic insights into energy conservation by flavin-based electron bifurcation

    Carolyn E. Lubner;David P. Jennings;David W. Mulder;Gerrit J. Schut

  • Trehalose 6‐phosphate phosphatase is required for cell wall integrity and fungal virulence but not trehalose biosynthesis in the human fungal pathogen Aspergillus fumigatus

    Srisombat Puttikamonkul;Sven D. Willger;Nora Grahl;John R. Perfect

  • Application of global metabolomic profiling of synovial fluid for osteoarthritis biomarkers

    Alyssa K. Carlson;Rachel A. Rawle;Erik Adams;Mark C. Greenwood

  • The Electron Bifurcating FixABCX Protein Complex from Azotobacter vinelandii: Generation of Low-Potential Reducing Equivalents for Nitrogenase Catalysis.

    Rhesa N. Ledbetter;Amaya M. Garcia Costas;Carolyn E. Lubner;David W. Mulder

  • Structures of sialylated fucosyl polylactosaminoglycans isolated from chronic myelogenous leukemia cells.

    M Fukuda;B Bothner;P Ramsamooj;A Dell

  • Characterization of the Archaeal Thermophile Sulfolobus Turreted Icosahedral Virus Validates an Evolutionary Link among Double-Stranded DNA Viruses from All Domains of Life

    Walid S. A. Maaty;Alice C. Ortmann;Mensur Dlakic;Katie Schulstad

  • Electrospray ionization of a whole virus: analyzing mass, structure, and viability.

    Brian Bothner;Gary Siuzdak

Frequent Co-Authors

John W. Peters
John W. Peters Washington State University
Gary Siuzdak
Gary Siuzdak Scripps Research Institute
John E. Johnson
John E. Johnson Scripps Research Institute
Mark J. Young
Mark J. Young Montana State University
Timothy R. McDermott
Timothy R. McDermott Montana State University
Paul W. King
Paul W. King National Renewable Energy Laboratory
Trevor Douglas
Trevor Douglas Indiana University
Lance C. Seefeldt
Lance C. Seefeldt Utah State University
Richard W. Kriwacki
Richard W. Kriwacki St. Jude Children's Research Hospital
Michael W. W. Adams
Michael W. W. Adams University of Georgia

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