D-Index & Metrics Best Publications
Richard W. Kriwacki

Richard W. Kriwacki

St. Jude Children's Research Hospital
United States

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • DNA
  • Enzyme

His primary areas of investigation include Organelle, Cell biology, Cancer research, Genetics and Nucleolus. His Organelle study combines topics from a wide range of disciplines, such as Biophysics, RNA metabolism and Nucleic acid. His Cell biology study frequently draws connections between related disciplines such as RNA.

In the field of Cancer research, his study on Glioma and Myeloid overlaps with subjects such as DNM2 and Haematopoiesis. When carried out as part of a general Genetics research project, his work on Stress granule, Nuclear pore, Translation and Interactome is frequently linked to work in C9orf72, therefore connecting diverse disciplines of study. He has researched Nucleolus in several fields, including Ribonucleoprotein, Rna processing, Macromolecule and Phase.

His most cited work include:

  • The genetic basis of early T-cell precursor acute lymphoblastic leukaemia (1109 citations)
  • Classification of intrinsically disordered regions and proteins. (962 citations)
  • Coexisting Liquid Phases Underlie Nucleolar Subcompartments (730 citations)

What are the main themes of his work throughout his whole career to date?

His primary scientific interests are in Cell biology, Biochemistry, Protein structure, Cyclin-dependent kinase and Crystallography. His study in Molecular biology extends to Cell biology with its themes. The Plasma protein binding, Protein domain, Amino acid and Calcitriol receptor research Richard W. Kriwacki does as part of his general Biochemistry study is frequently linked to other disciplines of science, such as p14arf, therefore creating a link between diverse domains of science.

Richard W. Kriwacki has included themes like Kinase, Proto-oncogene tyrosine-protein kinase Src, Cyclin-dependent kinase 2 and Polo-like kinase in his Cyclin-dependent kinase study. The study incorporates disciplines such as Protein secondary structure, Ligand, Biophysics, Protein folding and Nuclear magnetic resonance spectroscopy in addition to Crystallography. His Nucleolus research includes elements of Stress granule, Translation, Nuclear pore and Interactome.

He most often published in these fields:

  • Cell biology (56.06%)
  • Biochemistry (34.85%)
  • Protein structure (28.79%)

What were the highlights of his more recent work (between 2014-2020)?

  • Cell biology (56.06%)
  • Organelle (13.64%)
  • Nucleolus (19.70%)

In recent papers he was focusing on the following fields of study:

His primary areas of study are Cell biology, Organelle, Nucleolus, Ribosome and Phosphorylation. His studies deal with areas such as RNA, Nucleophosmin and Nucleic acid as well as Cell biology. Richard W. Kriwacki combines subjects such as Proteins metabolism, RNA metabolism and Stress signaling with his study of Organelle.

His work deals with themes such as Ribosomal protein, Function, Nuclear pore, Structural biology and Stress granule, which intersect with Nucleolus. His Ribosome research incorporates themes from Chemical physics, Molecular biology and Intrinsically disordered proteins. His Phosphorylation research is multidisciplinary, relying on both Cyclin-dependent kinase, Cyclin A, Tyrosine kinase and Cyclin-dependent kinase 2.

Between 2014 and 2020, his most popular works were:

  • Coexisting Liquid Phases Underlie Nucleolar Subcompartments (730 citations)
  • The whole-genome landscape of medulloblastoma subtypes (376 citations)
  • C9orf72 Dipeptide Repeats Impair the Assembly, Dynamics, and Function of Membrane-Less Organelles. (351 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • DNA
  • Enzyme

Richard W. Kriwacki mostly deals with Nucleolus, Organelle, C9orf72, Translation and Cell biology. His work carried out in the field of Nucleolus brings together such families of science as Biophysics, Rna processing and Phase. His Organelle study integrates concerns from other disciplines, such as Ribonucleoprotein and Macromolecule.

C9orf72 combines with fields such as Function, Nuclear pore, Stress granule, Genetics and Interactome in his investigation.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

The genetic basis of early T-cell precursor acute lymphoblastic leukaemia

Jinghui Zhang;Li Ding;Linda Holmfeldt;Gang Wu.
Nature (2012)

1608 Citations

Classification of intrinsically disordered regions and proteins.

Robin van der Lee;Robin van der Lee;Marija Buljan;Benjamin Lang;Robert J. Weatheritt.
Chemical Reviews (2014)

1557 Citations

Coexisting Liquid Phases Underlie Nucleolar Subcompartments

Marina Feric;Nilesh Vaidya;Tyler S. Harmon;Diana M. Mitrea.
Cell (2016)

956 Citations

The genomic landscape of diffuse intrinsic pontine glioma and pediatric non-brainstem high-grade glioma

Gang Wu;Alexander K Diaz;Alexander K Diaz;Barbara S Paugh;Sherri L Rankin.
Nature Genetics (2014)

866 Citations

Novel mutations target distinct subgroups of medulloblastoma

Giles Robinson;Matthew Parker;Tanya A. Kranenburg;Charles Lu;Charles Lu.
Nature (2012)

794 Citations

Structural studies of p21Waf1/Cip1/Sdi1 in the free and Cdk2-bound state: conformational disorder mediates binding diversity

Richard W. Kriwacki;Ludger Hengst;Linda Tennant;Steven I. Reed.
Proceedings of the National Academy of Sciences of the United States of America (1996)

702 Citations

Whole-genome sequencing identifies genetic alterations in pediatric low-grade gliomas

Jinghui Zhang;Gang Wu;Claudia P. Miller;Ruth G. Tatevossian.
Nature Genetics (2013)

677 Citations

The whole-genome landscape of medulloblastoma subtypes

Paul A. Northcott;Paul A. Northcott;Ivo Buchhalter;Ivo Buchhalter;A. Sorana Morrissy;Volker Hovestadt.
Nature (2017)

672 Citations

Phase separation in biology; functional organization of a higher order

Diana M. Mitrea;Richard W. Kriwacki;Richard W. Kriwacki.
Cell Communication and Signaling (2016)

411 Citations

C9orf72 Dipeptide Repeats Impair the Assembly, Dynamics, and Function of Membrane-Less Organelles.

Kyung Ha Lee;Peipei Zhang;Hong Joo Kim;Diana M. Mitrea.
Cell (2016)

408 Citations

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