Toshio Hakoshima

Overview

Best Publications

• Gibberellin-induced DELLA recognition by the gibberellin receptor GID1

  Kohji Murase;Yoshinori Hirano;Tai-ping Sun;Toshio Hakoshima

  781
  Citations

• Structural basis of the membrane-targeting and unmasking mechanisms of the radixin FERM domain.

  Keisuke Hamada;Toshiyuki Shimizu;Takeshi Matsui;Shoichiro Tsukita

  478
  Citations

• Structure of the human Cereblon–DDB1–lenalidomide complex reveals basis for responsiveness to thalidomide analogs

  Philip P Chamberlain;Antonia Lopez-Girona;Karen Miller;Gilles Carmel

  469
  Citations

• Structural basis for recruitment of human flap endonuclease 1 to PCNA.

  Shigeru Sakurai;Ken Kitano;Hiroto Yamaguchi;Keisuke Hamada

  336
  Citations

• Crystal structure of a multifunctional 2-Cys peroxiredoxin heme-binding protein 23 kDa/proliferation-associated gene product

  Shoko Hirotsu;Yasuko Abe;Kengo Okada;Noriyuki Nagahara

  334
  Citations

• Structures of D14 and D14L in the strigolactone and karrikin signaling pathways

  Megumi Kagiyama;Yoshinori Hirano;Tomoyuki Mori;Sun Yong Kim

  332
  Citations

• The Molecular Structure of a DNA-Triostin A Complex

  A. H.-J. Wang;G. Ughetto;G. J. Quigley;T. Hakoshima

  331
  Citations

• Crystal structure of human RhoA in a dominantly active form complexed with a GTP analogue.

  Kentaro Ihara;Sachiko Muraguchi;Masato Kato;Toshiyuki Shimizu

  319
  Citations

• Crystal structure of an IRF-DNA complex reveals novel DNA recognition and cooperative binding to a tandem repeat of core sequences.

  Yoshifumi Fujii;Toshiyuki Shimizu;Masahiro Kusumoto;Yoshimasa Kyogoku

  307
  Citations

• Structural basis for the specific inhibition of heterotrimeric Gq protein by a small molecule.

  Akiyuki Nishimura;Ken Kitano;Jun Takasaki;Masatoshi Taniguchi

  304
  Citations

• Crystal structure of PHO4 bHLH domain-DNA complex: flanking base recognition.

  Toshiyuki Shimizu;Atsuki Toumoto;Kentaro Ihara;Masato Shimizu

  291
  Citations

• AT base pairs are less stable than GC base pairs in Z-DNA: The crystal structure of d(m5CGTAm5CG)

  A.H.-J Wang;T Hakoshima;G.A Van Der Marel;J.H Van Boom

  251
  Citations

• Structural basis for the diversity of DNA recognition by bZIP transcription factors.

  Yoshifumi Fujii;Toshiyuki Shimizu;Takashi Toda;Mitsuhiro Yanagida

  247
  Citations

• Structural basis of adhesion-molecule recognition by ERM proteins revealed by the crystal structure of the radixin-ICAM-2 complex

  Keisuke Hamada;Toshiyuki Shimizu;Toshiyuki Shimizu;Shigenobu Yonemura;Shoichiro Tsukita

  232
  Citations

• Strigolactone perception and deactivation by a hydrolase receptor DWARF14

  Yoshiya Seto;Rei Yasui;Hiromu Kameoka;Muluneh Tamiru

  228
  Citations

• INSIGHTS INTO MULTISTEP PHOSPHORELAY FROM THE CRYSTAL STRUCTURE OF THE C-TERMINAL HPT DOMAIN OF ARCB

  Masato Kato;Takeshi Mizuno;Toshiyuki Shimizu;Toshio Hakoshima

  219
  Citations

• The structural basis of Rho effector recognition revealed by the crystal structure of human RhoA complexed with the effector domain of PKN/PRK1.

  Ryoko Maesaki;Kentaro Ihara;Toshiyuki Shimizu;Shinya Kuroda;Shinya Kuroda

  204
  Citations

• Molecular mechanism for the regulation of rho-kinase by dimerization and its inhibition by fasudil.

  Hiroto Yamaguchi;Miyuki Kasa;Miyuki Kasa;Mutsuki Amano;Kozo Kaibuchi

  200
  Citations

• Structural basis for tubulin recognition by cytoplasmic linker protein 170 and its autoinhibition

  Masaki Mishima;Ryoko Maesaki;Miyuki Kasa;Takashi Watanabe

  151
  Citations

• Structural basis for DNA strand separation by the unconventional winged-helix domain of RecQ helicase WRN

  Ken Kitano;Sun-Yong Kim;Toshio Hakoshima

  148
  Citations