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Biology and Biochemistry

D-Index
53
Citations
11258
World Ranking
16082
National Ranking
6667

Overview

Jeff Hardin is affiliated with the University of Wisconsin-Madison in the United States. Their research focuses primarily on Biochemistry, Genetics, and Molecular Biology, with significant contributions spanning topics such as Genetics, Aging, and Longevity in Model Organisms, Cellular Mechanics and Interactions, and Muscle Physiology and Disorders.

The scientist has published extensively, with 28 publications categorized under Biochemistry, Genetics, and Molecular Biology. Their work extends into subfields including Aging, Molecular Biology, Cell Biology, Plant Science, and Physiology. Central topics addressed in their research include Genetics, Aging, and Longevity in Model Organisms; Cellular Mechanics and Interactions; Spaceflight effects on biology; Muscle Physiology and Disorders; Biochemical and Structural Characterization; Rabbits: Nutrition, Reproduction, Health; and Plant Stress Responses and Tolerance.

Jeff Hardin's recent papers reflect a focus on cellular structures and mechanisms related to epidermal morphogenesis and adhesion in the model organism Caenorhabditis elegans. Key publications include:

  • "Polarized Rac-dependent protrusions drive epithelial intercalation in the embryonic epidermis of C. elegans," 2021, UNC Libraries
  • "TES-1/Tes and ZYX-1/Zyxin protect junctional actin networks under tension during epidermal morphogenesis in the C. elegans embryo," 2022, Current Biology
  • "Single-molecule force spectroscopy reveals intra- and intermolecular interactions of Caenorhabditis elegans HMP-1 during mechanotransduction," 2024, Proceedings of the National Academy of Sciences
  • "C. elegans srGAP is an α-catenin M domain-binding protein that strengthens cadherin-dependent adhesion during morphogenesis," 2022, Development
  • "Imaging Epidermal Cell Rearrangement in the C. elegans Embryo," 2022, Methods in molecular biology

Their publication venues frequently include bioRxiv (Cold Spring Harbor Laboratory), UNC Libraries, Proceedings of the National Academy of Sciences, Current Biology, and Methods in molecular biology. Six publications appear in bioRxiv, while two are found in UNC Libraries.

Jeff Hardin has collaborated multiple times with several coauthors, among them Sterling C.T. Martin, Joel M. Serre, Bob Goldstein, Yuyun Zhu, and Bethany Lucas. Sterling C.T. Martin has coauthored seven papers, Joel M. Serre five, Bob Goldstein four, Yuyun Zhu three, and Bethany Lucas three.

Best Publications

  • Targeted disruption of the flk2/flt3 gene leads to deficiencies in primitive hematopoietic progenitors

    Katrin Mackarehtschian;Jeff D. Hardin;Katrd A. Moore;Sharon Boast

  • A Putative Catenin–Cadherin System Mediates Morphogenesis of the Caenorhabditis elegans Embryo

    Michael Costa;William Raich;Cristina Agbunag;Ben Leung

  • Mice homozygous for the ablm1 mutation show poor viability and depletion of selected B and T cell populations

    Pamela L. Schwartzberg;Alan M. Stall;Jeff D. Hardin;Katherine S. Bowdish

  • Semaphorin and Eph receptor signaling guide a series of cell movements for ventral enclosure in C. elegans

    Richard Ikegami;Richard Ikegami;Kristin Simokat;Hong Zheng;Louise Brown

  • Dynamics and ultrastructure of developmental cell fusions in the Caenorhabditis elegans hypodermis

    William A. Mohler;Jeffrey S. Simske;Ellen M. Williams-Masson;Jeffrey D. Hardin

  • Cooperative regulation of AJM-1 controls junctional integrity in Caenorhabditis elegans epithelia

    Mathias Köppen;Jeffrey S. Simske;Paul A. Sims;Bonnie L. Firestein

  • MEX-3 Is a KH Domain Protein That Regulates Blastomere Identity in Early C. elegans Embryos

    Bruce W Draper;Craig C Mello;Bruce Bowerman;Jeff Hardin

  • The World of the Cell

    Wayne M. Becker;Lewis J. Kleinsmith;Jeff Hardin

  • Cytokinesis and Midzone Microtubule Organization in Caenorhabditis elegans Require the Kinesin-like Protein ZEN-4

    William B. Raich;Adrienne N. Moran;Joel H. Rothman;Jeff Hardin

  • The VAB-1 Eph Receptor Tyrosine Kinase Functions in Neural and Epithelial Morphogenesis in C. elegans

    Sean E George;Kristin Simokat;Jeff Hardin;Andrew D Chisholm

  • An actin-mediated two-step mechanism is required for ventral enclosure of the C. elegans hypodermis

    Ellen M. Williams-Masson;Amy N. Malik;Jeff Hardin

  • Rapid epithelial-sheet sealing in the Caenorhabditis elegans embryo requires cadherin-dependent filopodial priming

    William B. Raich;Cristina Agbunag;Jeff Hardin

  • Making and breaking contacts: the cellular biology of cadherin regulation

    Alpha S Yap;Matthew S Crampton;Jeff Hardin

  • The behaviour and function of bottle cells during gastrulation of Xenopus laevis.

    J. Hardin;R. Keller

  • Establishment of a tissue-specific RNAi system in C. elegans.

    Hiroshi Qadota;Makiko Inoue;Takao Hikita;Mathias Köppen

  • Cell intercalation from top to bottom.

    Elise Walck-Shannon;Jeff Hardin

  • The mechanisms and mechanics of archenteron elongation during sea urchin gastrulation

    Jeffrey D. Hardin;Louis Y. Cheng

  • Commitment along the dorsoventral axis of the sea urchin embryo is altered in response to NiCl2

    J. Hardin;J.A. Coffman;S.D. Black;D.R. McClay

  • The cellular mechanism of epithelial rearrangement during morphogenesis of the Caenorhabditis elegans dorsal hypodermis.

    E.M. Williams-Masson;P.J. Heid;C.A. Lavin;J. Hardin

  • Multiple Wnt Signaling Pathways Converge to Orient the Mitotic Spindle in Early C. elegans Embryos

    Timothy Walston;Christina Tuskey;Lois Edgar;Nancy Hawkins

Frequent Co-Authors

Andrew D. Chisholm
Andrew D. Chisholm University of California, San Diego
Judith Kimble
Judith Kimble University of Wisconsin–Madison
David R. McClay
David R. McClay Duke University
William I. Weis
William I. Weis Stanford University
Ray Keller
Ray Keller University of Virginia
James R. Priess
James R. Priess University of Washington
John G. White
John G. White University of Wisconsin–Madison
Anjon Audhya
Anjon Audhya University of Wisconsin–Madison
W. James Nelson
W. James Nelson Stanford University
John F. Fallon
John F. Fallon University of Wisconsin–Madison

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