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Molecular Biology

D-Index
46
Citations
9233
World Ranking
2803
National Ranking
1346

Overview

Joel H. Rothman is affiliated with the University of California, Santa Barbara in the United States. Their work spans several areas within biochemistry, genetics, molecular biology, and medicine, with a focus on the biological mechanisms of aging and development.

The main fields of study represented in Rothman's research include:

  • Biochemistry, Genetics and Molecular Biology
  • Medicine

Within these broader fields, Rothman has contributed notably to the following subfields:

  • Aging
  • Molecular Biology
  • Physiology
  • Ecology, Evolution, Behavior and Systematics
  • Cellular and Molecular Neuroscience

Their research covers several key scientific topics, including:

  • Genetics, Aging, and Longevity in Model Organisms
  • CRISPR and Genetic Engineering
  • Spaceflight effects on biology
  • Birth, Development, and Health
  • Circadian rhythm and melatonin
  • Biocrusts and Microbial Ecology
  • Pluripotent Stem Cells Research

Joel H. Rothman's publication record features contributions to various journals and platforms. Frequent publication venues include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Visualized Experiments
  • Transplantation and Cellular Therapy
  • Advanced Biology
  • Frontiers in Cell and Developmental Biology

Rothman has collaborated with several researchers repeatedly, including:

  • Pradeep M. Joshi
  • Chee Kiang Ewe
  • Sagen E. Flowers
  • Yamila N. Torres Cleuren
  • Geneva Alok

Notable recent papers authored or co-authored by Rothman include:

  • "Evolution and Developmental System Drift in the Endoderm Gene Regulatory Network of Caenorhabditis and Other Nematodes" (2020), published in Frontiers in Cell and Developmental Biology
  • "Natural cryptic variation in epigenetic modulation of an embryonic gene regulatory network" (2020), published in Proceedings of the National Academy of Sciences
  • "Stressful development: integrating endoderm development, stress, and longevity" (2020), published in Developmental Biology
  • "Feedforward regulatory logic controls the specification-to-differentiation transition and terminal cell fate during Caenorhabditis elegans endoderm development" (2022), published in Development
  • "An Autonomous Molecular Bioluminescent Reporter (AMBER) for Voltage Imaging in Freely Moving Animals" (2021), published in Advanced Biology

Best Publications

  • Caenorhabditis elegans p53: Role in Apoptosis, Meiosis, and Stress Resistance

    W. Brent Derry;Aaron P. Putzke;Joel H. Rothman

  • Acidification of the lysosome-like vacuole and the vacuolar H+-ATPase are deficient in two yeast mutants that fail to sort vacuolar proteins.

    Joel H. Rothman;Carl T. Yamashiro;Christopher K. Raymond;Patricia M. Kane

  • Protein sorting in yeast: Mutants defective in vacuole biogenesis mislocalize vacuolar proteins into the late secretory pathway

    Joel H. Rothman;Tom H. Stevens

  • PEP4 gene of Saccharomyces cerevisiae encodes proteinase A, a vacuolar enzyme required for processing of vacuolar precursors.

    G Ammerer;C P Hunter;J H Rothman;G C Saari

  • Protein sorting in yeast: the localization determinant of yeast vacuolar carboxypeptidase Y resides in the propeptide.

    Luis A. Valls;Craig P. Hunter;Joel H. Rothman;Tom H. Stevens

  • Cytokinesis and Midzone Microtubule Organization in Caenorhabditis elegans Require the Kinesin-like Protein ZEN-4

    William B. Raich;Adrienne N. Moran;Joel H. Rothman;Jeff Hardin

  • A putative GTP binding protein homologous to interferon-inducible Mx proteins performs an essential function in yeast protein sorting

    Joel H. Rothman;Christopher K. Raymond;Teresa Gilbert;Patrick J. O'Hara

  • Characterization of genes required for protein sorting and vacuolar function in the yeast Saccharomyces cerevisiae.

    J. H. Rothman;I. Howald;T. H. Stevens

  • end-1 encodes an apparent GATA factor that specifies the endoderm precursor in Caenorhabditis elegans embryos

    Jiangwen Zhu;Russell J. Hill;Paul J. Heid;Masamitsu Fukuyama;Masamitsu Fukuyama

  • Baculovirus p35 prevents developmentally programmed cell death and rescues a ced-9 mutant in the nematode Caenorhabditis elegans.

    Asako Sugimoto;Paul D. Friesen;Joel H. Rothman

  • Restriction of Mesendoderm to a Single Blastomere by the Combined Action of SKN-1 and a GSK-3β Homolog Is Mediated by MED-1 and -2 in C. elegans

    Morris F Maduro;Marc D Meneghini;Bruce Bowerman;Gina Broitman-Maduro

  • Making worm guts: the gene regulatory network of the Caenorhabditis elegans endoderm.

    Morris F. Maduro;Joel H. Rothman

  • Gene dosage-dependent secretion of yeast vacuolar carboxypeptidase Y

    T H Stevens;J H Rothman;G S Payne;R Schekman

  • ELT-5 and ELT-6 are required continuously to regulate epidermal seam cell differentiation and cell fusion in C. elegans.

    Kyunghee Koh;Joel H. Rothman

  • C. elegans DAF-18/PTEN mediates nutrient-dependent arrest of cell cycle and growth in the germline

    Masamitsu Fukuyama;Masamitsu Fukuyama;Ann E. Rougvie;Joel H. Rothman

  • Reprogramming of early embryonic blastomeres into endodermal progenitors by a Caenorhabditis elegans GATA factor

    Jiangwen Zhu;Tetsunari Fukushige;James D. McGhee;Joel H. Rothman

  • Structure, biosynthesis, and localization of dipeptidyl aminopeptidase B, an integral membrane glycoprotein of the yeast vacuole.

    C J Roberts;G Pohlig;J H Rothman;T H Stevens

  • Overproduction-induced mislocalization of a yeast vacuolar protein allows isolation of its structural gene

    Joel H. Rothman;Craig P. Hunter;Luis A. Valls;Tom H. Stevens

  • dad-1, an endogenous programmed cell death suppressor in Caenorhabditis elegans and vertebrates.

    Asako Sugimoto;Rebecca R. Hozak;Torahiko Nakashima;Takeharu Nishimoto

  • Suppression of CED-3-independent apoptosis by mitochondrial βNAC in Caenorhabditis elegans

    Tim A. Bloss;Eric S. Witze;Joel H. Rothman

Frequent Co-Authors

Tom H. Stevens
Tom H. Stevens University of Oregon
Russell G. Snell
Russell G. Snell University of Auckland
James R. Priess
James R. Priess University of Washington
Thomas Stevens
Thomas Stevens Uppsala University
Craig P. Hunter
Craig P. Hunter Harvard University
Patricia M. Kane
Patricia M. Kane SUNY Upstate Medical University
James D. McGhee
James D. McGhee Alberta Children's Hospital
David H. Hall
David H. Hall Albert Einstein College of Medicine
Jeff Hardin
Jeff Hardin University of Wisconsin–Madison
Thanos D. Halazonetis
Thanos D. Halazonetis University of Geneva

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