Patricia M. Kane

Overview

Best Publications

• Integration of chemical-genetic and genetic interaction data links bioactive compounds to cellular target pathways

  Ainslie B Parsons;Renée L Brost;Huiming Ding;Zhijian Li

  755
  Citations

• Protein splicing converts the yeast TFP1 gene product to the 69-kD subunit of the vacuolar H(+)-adenosine triphosphatase.

  Patricia M. Kane;Carl T. Yamashiro;David F Wolczyk;Norma Neff

  664
  Citations

• Disassembly and Reassembly of the Yeast Vacuolar H+-ATPase in Vivo

  Patricia M. Kane

  558
  Citations

• Acidification of the lysosome-like vacuole and the vacuolar H+-ATPase are deficient in two yeast mutants that fail to sort vacuolar proteins.

  Joel H. Rothman;Carl T. Yamashiro;Christopher K. Raymond;Patricia M. Kane

  555
  Citations

• The yeast lysosome-like vacuole: endpoint and crossroads.

  Sheena Claire Li;Patricia M. Kane

  493
  Citations

• The Where, When, and How of Organelle Acidification by the Yeast Vacuolar H+-ATPase

  Patricia M. Kane

  487
  Citations

• Vacuolar and Plasma Membrane Proton Pumps Collaborate to Achieve Cytosolic pH Homeostasis in Yeast

  Gloria A. Martínez-Muñoz;Patricia Kane

  295
  Citations

• Reversible Association between the V1 and V0 Domains of Yeast Vacuolar H+-ATPase Is an Unconventional Glucose-Induced Effect

  Karlett J. Parra;Patricia M. Kane

  254
  Citations

• Role of vacuolar acidification in protein sorting and zymogen activation: a genetic analysis of the yeast vacuolar proton-translocating ATPase.

  C T Yamashiro;P M Kane;D F Wolczyk;R A Preston

  231
  Citations

• The RAVE Complex Is Essential for Stable Assembly of the Yeast V-ATPase

  Anne M. Smardon;Maureen Tarsio;Patricia M. Kane

  228
  Citations

• Assembly and targeting of peripheral and integral membrane subunits of the yeast vacuolar H(+)-ATPase.

  P M Kane;M C Kuehn;I Howald-Stevenson;T H Stevens

  223
  Citations

• Biochemical characterization of the yeast vacuolar H(+)-ATPase.

  P. M. Kane;Carl Yamashiro;T. H. Stevens

  215
  Citations

• The H Subunit (Vma13p) of the Yeast V-ATPase Inhibits the ATPase Activity of Cytosolic V1 Complexes

  Karlett J. Parra;Kelly L. Keenan;Patricia M. Kane

  189
  Citations

• Assembly and regulation of the yeast vacuolar H(+)-ATPase.

  Patricia M. Kane;Karlett J. Parra

  178
  Citations

• Structure of the yeast vacuolar ATPase.

  Zhenyu Zhang;Yesha Zheng;Hortense Mazon;Elena Milgrom

  156
  Citations

• The signaling lipid PI(3,5)P2 stabilizes V1–Vo sector interactions and activates the V-ATPase

  Sheena Claire Li;Theodore T. Diakov;Tao Xu;Maureen Tarsio

  151
  Citations

• Partial assembly of the yeast vacuolar H(+)-ATPase in mutants lacking one subunit of the enzyme

  R D Doherty;P M Kane

  135
  Citations

• Loss of vacuolar proton-translocating ATPase activity in yeast results in chronic oxidative stress.

  Elena Milgrom;Heba Diab;Frank Middleton;Patricia M. Kane

  124
  Citations

• The long physiological reach of the yeast vacuolar H+-ATPase.

  Patricia M. Kane

  124
  Citations

• Targeting reversible disassembly as a mechanism of controlling V-ATPase activity.

  Patricia M. Kane

  122
  Citations