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John L. Rubinstein

John L. Rubinstein

D-Index & Metrics

Biology and Biochemistry

D-Index
54
Citations
19430
World Ranking
15359
National Ranking
539

Research.com Recognitions

  • 2013 - Burton Medal, Mineralogical Society of America

Overview

John L. Rubinstein is affiliated with the University of Toronto in Canada. Their research contributions span several fields with a primary focus on biochemistry, genetics, and molecular biology. Within these broader domains, Rubinstein's work delves deeply into molecular biology, infectious diseases, structural biology, cell biology, and epidemiology.

The scientist's research encompasses numerous key topics including ATP synthase and ATPases, photosynthetic processes and mechanisms, advanced electron microscopy techniques and applications, RNA and protein synthesis mechanisms, mitochondrial function and pathology, biochemical and molecular research, and tuberculosis research and epidemiology.

Rubinstein has published extensively, with a notable presence in venues such as bioRxiv (Cold Spring Harbor Laboratory), the Proceedings of the National Academy of Sciences, Nature Communications, eLife, and Structure. These outlets highlight a strong engagement with cutting-edge research and collaborations within the life sciences.

Frequent coauthors working alongside Rubinstein include Stephanie A. Bueler, Jean-Philippe Julien, Peter Brzezinski, Justin M. Di Trani, and Samir Benlekbir. The collaboration with these researchers indicates ongoing partnerships likely contributing across multiple projects and publications.

Recent publications by Rubinstein include the following works:

  • Structure of V-ATPase from the mammalian brain (2020), published in Science
  • Structure and Roles of V-type ATPases (2020), published in Trends in Biochemical Sciences
  • Structure of mycobacterial ATP synthase bound to the tuberculosis drug bedaquiline (2020), published in Nature
  • Electron-event representation data enable efficient cryoEM file storage with full preservation of spatial and temporal resolution (2020), published in IUCrJ
  • A processive rotary mechanism couples substrate unfolding and proteolysis in the ClpXP degradation machinery (2020), published in eLife

Rubinstein received the Burton Medal from the Mineralogical Society of America in 2013.

Best Publications

  • Structure and conformational states of the bovine mitochondrial ATP synthase by cryo-EM

    Anna Zhou;Alexis Rohou;Daniel G Schep;John V Bason

  • Structure of the mitochondrial ATP synthase by electron cryomicroscopy

    John L. Rubinstein;John L. Rubinstein;John E. Walker;Richard Henderson

  • The structural basis of modified nucleosome recognition by 53BP1

    Marcus D Wilson;Samir Benlekbir;Amélie Fradet-Turcotte;Amélie Fradet-Turcotte;Alana Sherker;Alana Sherker

  • Structure of the Alternative Complex III in a Supercomplex with Cytochrome Oxidase

    Chang Sun;Samir Benlekbir;Padmaja Venkatakrishnan;Yuhang Wang

  • The human coronavirus HCoV‐229E S‐protein structure and receptor binding

    Zhijie Li;Aidan C.A. Tomlinson;Alan H.M. Wong;Dongxia Zhou

  • Atomic model for the dimeric FO region of mitochondrial ATP synthase.

    Hui Guo;Stephanie A. Bueler;John L. Rubinstein

  • Eukaryotic V-ATPase: Novel structural findings and functional insights

    Vladimir Marshansky;John L. Rubinstein;Gerhard Grüber;Gerhard Grüber

  • Structure and Roles of V-type ATPases

    Thamiya Vasanthakumar;John L. Rubinstein

  • Structure of V-ATPase from the mammalian brain.

    Yazan M. Abbas;Di Wu;Stephanie A. Bueler;Carol V. Robinson

  • Structure of a bacterial ATP synthase.

    Hui Guo;Toshiharu Suzuki;John L Rubinstein

  • Tilt-Pair Analysis of Images from a Range of Different Specimens in Single-Particle Electron Cryomicroscopy

    Richard Henderson;Shaoxia Chen;James Z. Chen;Nikolaus Grigorieff

  • Adaptor protein self-assembly drives the control of a cullin-RING ubiquitin ligase.

    Wesley J. Errington;M. Qasim Khan;Stephanie A. Bueler;John L. Rubinstein

  • Assembly and structural analysis of a covalently closed nano-scale DNA cage

    Felicie F. Andersen;Bjarne Knudsen;Cristiano Luis Pinto Oliveira;Rikke F. Frøhlich

  • Inhibition of mitochondrial translation overcomes venetoclax resistance in AML through activation of the integrated stress response

    David Sharon;Severine Cathelin;Sara Mirali;Justin M. Di Trani

  • Structure of mycobacterial ATP synthase bound to the tuberculosis drug bedaquiline.

    Hui Guo;Gautier M. Courbon;Stephanie A. Bueler;Juntao Mai

  • Arrangement of subunits in intact mammalian mitochondrial ATP synthase determined by cryo-EM

    Lindsay A. Baker;Ian N. Watt;Michael J. Runswick;John E. Walker

  • Bacterial polysaccharide co-polymerases share a common framework for control of polymer length.

    Ante Tocilj;Christine Munger;Ariane Proteau;Renato Morona

  • An autoinhibited structure of α-catenin and its implications for vinculin recruitment to adherens junctions.

    Noboru Ishiyama;Nobutoshi Tanaka;Kentaro Abe;Yoo Jeong Yang

  • Subnanometre-resolution structure of the intact Thermus thermophilus H + -driven ATP synthase

    Wilson C. Y. Lau;John L. Rubinstein

  • Structure of the Alternative Complex III in a supercomplex with cytochrome oxidase

    Robert B. Gennis;Chang Sun;Samir Benlekbir;Padmaja Venkatakrishnan

Frequent Co-Authors

Lewis E. Kay
Lewis E. Kay University of Toronto
Jean-Philippe Julien
Jean-Philippe Julien University of Toronto
John E. Walker
John E. Walker University of Cambridge
Peter Brzezinski
Peter Brzezinski Stockholm University
Lori L. Burrows
Lori L. Burrows McMaster University
Daniel Durocher
Daniel Durocher Lunenfeld-Tanenbaum Research Institute
Toshiharu Suzuki
Toshiharu Suzuki Hokkaido University
P. Lynne Howell
P. Lynne Howell University of Toronto
Nikolaus Grigorieff
Nikolaus Grigorieff Howard Hughes Medical Institute
Régis Pomès
Régis Pomès University of Toronto

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