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Genetics

D-Index
47
Citations
28476
World Ranking
4076
National Ranking
6

Overview

Russell G. Snell is affiliated with the University of Auckland in New Zealand and has a research portfolio primarily focused on biochemistry, genetics, and molecular biology with contributions extending into medicine. Their research spans several subfields including molecular biology, genetics, infectious diseases, cellular and molecular neuroscience, and physiology.

Snell's work covers a variety of specific topics such as:

  • CRISPR and genetic engineering
  • Animal genetics and reproduction
  • Genetic neurodegenerative diseases
  • Genetic and phenotypic traits in livestock
  • Mitochondrial function and pathology
  • Genetic mapping and diversity in plants and animals
  • Single-cell and spatial transcriptomics

The scientist has contributed to recent papers including:

  • From Pathogenesis to Therapeutics: A Review of 150 Years of Huntington's Disease Research, 2023, International Journal of Molecular Sciences
  • DNA methylation study of Huntington's disease and motor progression in patients and in animal models, 2020, Nature Communications
  • Castration delays epigenetic aging and feminizes DNA methylation at androgen-regulated loci, 2021, eLife
  • A Review of the Current Mammalian Models of Alzheimer's Disease and Challenges That Need to Be Overcome, 2021, International Journal of Molecular Sciences
  • Genome-wide association studies of lactation yields of milk, fat, protein and somatic cell score in New Zealand dairy goats, 2020, Journal of Animal Science and Biotechnology

Frequent publication venues for Snell's work include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Genetics Selection Evolution
  • Expert Review of Clinical Immunology
  • International Journal of Molecular Sciences
  • eLife

Collaborations have been established with multiple coauthors, among them:

  • Klaus Lehnert
  • Jessie C. Jacobsen
  • Andrew Jiang
  • Renée R. Handley
  • Mathew D. Littlejohn

The scientist's research contributes to better understanding complex genetic mechanisms and molecular pathways, particularly in the context of neurodegenerative diseases like Huntington's and Alzheimer's, as well as in livestock genetics and reproductive biology.

Best Publications

  • A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes

    Marcy E. MacDonald;Christine M. Ambrose;Mabel P. Duyao;Richard H. Myers

  • A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes. The Huntington's Disease Collaborative Research Group.

    M Shah;N Datson;L Srinidhi;VP Stanton

  • Molecular basis of myotonic dystrophy: Expansion of a trinucleotide (CTG) repeat at the 3′ end of a transcript encoding a protein kinase family member

    J. David Brook;Mila E. McCurrach;Helen G. Harley;Alan J. Buckler

  • Identification of the tuberous sclerosis gene TSC1 on chromosome 9q34

    Marjon van Slegtenhorst;Ronald de Hoogt;Caroline Hermans;Mark Nellist

  • Positional candidate cloning of a QTL in dairy cattle: identification of a missense mutation in the bovine DGAT1 gene with major effect on milk yield and composition.

    Bernard Grisart;Wouter Coppieters;Frédéric Farnir;Latifa Karim

  • Relationship between trinucleotide repeat expansion and phenotypic variation in Huntington's disease

    Russell G. Snell;John C. MacMillan;Jeremy Peter Cheadle;Iain Fenton

  • Interaction Between Hamartin and Tuberin, the TSC1 and TSC2 Gene Products

    Marjon van Slegtenhorst;Mark Nellist;Bas Nagelkerken;Jeremy Cheadle

  • Molecular dissection of a quantitative trait locus: a phenylalanine-to-tyrosine substitution in the transmembrane domain of the bovine growth hormone receptor is associated with a major effect on milk yield and composition.

    Sarah Blott;Jong-Joo Kim;Sirja Moisio;Anne Schmidt-Küntzel

  • Molecular Genetic and Phenotypic Analysis Reveals Differences between TSC1 and TSC2 Associated Familial and Sporadic Tuberous Sclerosis

    Alistair C. Jones;Claire E. Daniells;Russell G. Snell;Maria Tachataki

  • Characterization of the DGAT1 gene in the New Zealand dairy population

    R.J. Spelman;C.A. Ford;P. McElhinney;G.C. Gregory

  • Complex reorganization and predominant non-homologous repair following chromosomal breakage in karyotypically balanced germline rearrangements and transgenic integration

    Colby Chiang;Jessie C Jacobsen;Carl Ernst;Carrie Hanscom

  • An ovine transgenic Huntington's disease model

    Jessie C. Jacobsen;C. Simon Bawden;Skye R. Rudiger;Clive J. McLaughlan

  • Sequence-based Association Analysis Reveals an MGST1 eQTL with Pleiotropic Effects on Bovine Milk Composition.

    Mathew D. Littlejohn;Mathew D. Littlejohn;Kathryn Tiplady;Tania A. Fink;Klaus Lehnert

  • Hyperekplexia associated with compound heterozygote mutations in the β-subunit of the human inhibitory glycine receptor (GLRB)

    Mark I. Rees;Trevor M. Lewis;John B. J. Kwok;Geert R. Mortier

  • Functionally reciprocal mutations of the prolactin signalling pathway define hairy and slick cattle.

    Mathew D. Littlejohn;Kristen M. Henty;Kathryn Tiplady;Thomas Johnson

  • Isoform heterogeneity of the human gephyrin gene (GPHN), binding domains to the glycine receptor, and mutation analysis in hyperekplexia

    Mark I. Rees;Kirsten Harvey;Hamish Ward;Julia H. White

  • Molecular analysis and clinical correlations of the Huntington's disease mutation

    J. C. MacMillan;R. G. Snell;A. Tyler;G. D. Houlihan

  • Mutation in Bovine β-Carotene Oxygenase 2 Affects Milk Color

    S. D. Berry;S. R. Davis;E. M. Beattie;N. L. Thomas

  • TATA-binding protein in neurodegenerative disease.

    W.M.C. van Roon-Mom;S.J. Reid;R.L.M. Faull;R.G. Snell

  • Molecular dissection of a quantitative trait locus: a phenylalanine-to-tyrosine substitution in the transmembrane domain of the bovine growth hormone receptor is associated with a major effect on milk yield and composition.

    Wouter Coppieters;Sarah C. Blott;Michel Georges;Richard J. Spelman

Frequent Co-Authors

Richard Spelman
Richard Spelman Livestock Improvement Corporation
Richard L.M. Faull
Richard L.M. Faull University of Auckland
Marcy E. MacDonald
Marcy E. MacDonald Harvard University
Henry J. Waldvogel
Henry J. Waldvogel University of Auckland
Mark I. Rees
Mark I. Rees Swansea University
Peter S. Harper
Peter S. Harper Cardiff University
James F. Gusella
James F. Gusella Harvard University
Joel H. Rothman
Joel H. Rothman University of California, Santa Barbara
Michael John Owen
Michael John Owen Cardiff University
Dorian J. Garrick
Dorian J. Garrick Massey University

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