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Chemistry

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74
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18998
World Ranking
4717
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1487

Biology and Biochemistry

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83
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22322
World Ranking
3547
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Research.com Recognitions

  • 2000 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Daniel E. Goldberg is affiliated with Washington University in St. Louis in the United States. Their primary field of study is Medicine, with a particular focus on subfields including Public Health, Environmental and Occupational Health, Molecular Biology, Immunology, Epidemiology, and Oncology.

Their research topics cover a range of subjects prominently related to infectious diseases and immunology. Notable areas include Malaria Research and Control, Mosquito-borne Diseases and Control, Complement System in Diseases, Invertebrate Immune Response Mechanisms, Computational Drug Discovery Methods, RNA and Protein Synthesis Mechanisms, and Drug Transport and Resistance Mechanisms.

Recent publications by Daniel E. Goldberg highlight their work in malaria research and drug discovery. Selected papers include:

  • MalDA, Accelerating Malaria Drug Discovery (2021, Trends in Parasitology)
  • Malaria parasite plasmepsins: More than just plain old degradative pepsins (2020, Journal of Biological Chemistry)
  • Multistage and transmission-blocking targeted antimalarials discovered from the open-source MMV Pandemic Response Box (2021, Nature Communications)
  • Prioritization of Molecular Targets for Antimalarial Drug Discovery (2021, ACS Infectious Diseases)
  • EXP1 is required for organisation of EXP2 in the intraerythrocytic malaria parasite vacuole (2020, Cellular Microbiology)

Frequent co-authors in their research include:

  • Eva S. Istvan
  • Elizabeth A. Winzeler
  • Alexander J. Polino
  • David A. Fidock
  • Jacquin C. Niles

Their publications are often found in these journals and platforms:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • ACS Infectious Diseases
  • Journal of Biological Chemistry
  • Journal of Education and Development

In recognition of contributions to the scientific community, Daniel E. Goldberg was awarded the status of Fellow of the American Association for the Advancement of Science (AAAS) in 2000.

Best Publications

  • Hemoglobin metabolism in the malaria parasite Plasmodium falciparum.

    Susan E. Francis;David J. Sullivan;Daniel E. Goldberg

  • An iron-carboxylate bond links the heme units of malaria pigment

    Andrew F. G. Slater;William J. Swiggard;Brian R. Orton;William D. Flitter

  • On the molecular mechanism of chloroquine's antimalarial action.

    David J. Sullivan;Ilya Y. Gluzman;David G. Russell;Daniel E. Goldberg

  • Hemoglobin degradation in the malaria parasite Plasmodium falciparum: an ordered process in a unique organelle.

    Daniel E. Goldberg;Andrew F. G. Slater;Anthony Cerami;Graeme B. Henderson

  • Four plasmepsins are active in the Plasmodium falciparum food vacuole, including a protease with an active-site histidine

    Ritu Banerjee;Jun Liu;Wandy Beatty;Lorraine Pelosof

  • Plasmodium Hemozoin Formation Mediated by Histidine-Rich Proteins

    David J. Sullivan;Ilya Y. Gluzman;Daniel E. Goldberg

  • Plasmodium falciparum ensures its amino acid supply with multiple acquisition pathways and redundant proteolytic enzyme systems

    Jun Liu;Eva S. Istvan;Ilya Y. Gluzman;Julia Gross

  • Aspartic proteases of Plasmodium falciparum and other parasitic protozoa as drug targets

    Graham H. Coombs;Daniel E. Goldberg;Michael Klemba;Colin Berry

  • Order and specificity of the Plasmodium falciparum hemoglobin degradation pathway.

    I Y Gluzman;S E Francis;A Oksman;C E Smith

  • Structure and inhibition of plasmepsin II, a hemoglobin-degrading enzyme from Plasmodium falciparum.

    A M Silva;A Y Lee;S V Gulnik;P Maier

  • Plasmepsin V licenses Plasmodium proteins for export into the host erythrocyte

    Ilaria Russo;Ilaria Russo;Shalon Babbitt;Vasant Muralidharan;Tamira Butler

  • HEMOGLOBIN DEGRADATION IN THE HUMAN MALARIA PATHOGEN PLASMODIUM FALCIPARUM: A CATABOLIC PATHWAY INITIATED BY A SPECIFIC ASPARTIC PROTEASE

    D. E. Goldberg;A. F. G. Slater;R. Beavis;B. Chait

  • Identification and characterization of falcilysin, a metallopeptidase involved in hemoglobin catabolism within the malaria parasite Plasmodium falciparum.

    Kathleen Kolakovich Eggleson;Kevin L. Duffin;Daniel E. Goldberg

  • Molecular characterization and inhibition of a Plasmodium falciparum aspartic hemoglobinase.

    S.E. Francis;I.Y. Gluzman;A. Oksman;A. Knickerbocker

  • Evidence for extensive subcellular organization of asparagine-linked oligosaccharide processing and lysosomal enzyme phosphorylation.

    D E Goldberg;S Kornfeld

  • An FKBP destabilization domain modulates protein levels in Plasmodium falciparum

    Christopher M Armstrong;Daniel E Goldberg

  • Malaria parasite exit from the host erythrocyte: A two-step process requiring extraerythrocytic proteolysis

    Brandy L. Salmon;Anna Oksman;Daniel E. Goldberg

  • Biological roles of proteases in parasitic protozoa.

    Michael Klemba;Daniel E Goldberg

  • PTEX component HSP101 mediates export of diverse malaria effectors into host erythrocytes

    Josh R Beck;Vasant Muralidharan;Anna Oksman;Daniel E Goldberg

  • A common mechanism for blockade of heme polymerization by antimalarial quinolines

    David J. Sullivan;Hugues Matile;Robert G. Ridley;Daniel E. Goldberg

Frequent Co-Authors

Elizabeth A. Winzeler
Elizabeth A. Winzeler University of California, San Diego
Joshua Zimmerberg
Joshua Zimmerberg National Institutes of Health
Choukri Ben Mamoun
Choukri Ben Mamoun Yale University
David J. Sullivan
David J. Sullivan Johns Hopkins University
Stuart Kornfeld
Stuart Kornfeld Washington University in St. Louis
Manuel Llinás
Manuel Llinás Pennsylvania State University
Dyann F. Wirth
Dyann F. Wirth Harvard University
John E. Heuser
John E. Heuser Washington University in St. Louis
David R. Sherman
David R. Sherman University of Washington
Christian Doerig
Christian Doerig RMIT University

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