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Neuroscience

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103
Citations
41357
World Ranking
682
National Ranking
381

Medicine

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103
Citations
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World Ranking
7329
National Ranking
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Overview

Edward Rockenstein is affiliated with the University of California, San Diego, United States. Their research primarily spans the fields of Medicine and Neuroscience, with a focus on Neurology, Molecular Biology, Cellular and Molecular Neuroscience, Physiology, and Pediatrics, Perinatology, and Child Health. The scientist's work addresses a range of neurological disorders and mechanisms.

Their main research topics include:

  • Parkinson's Disease Mechanisms and Treatments
  • Alzheimer's disease research and treatments
  • Neuroinflammation and Neurodegeneration Mechanisms
  • RNA Interference and Gene Delivery
  • Nuclear Receptors and Signaling
  • Neurological disorders and treatments
  • Nicotinic Acetylcholine Receptors Study

Edward Rockenstein has published several recent papers, notably:

  • "The Leukotriene Receptor Antagonist Montelukast Reduces Alpha-Synuclein Load and Restores Memory in an Animal Model of Dementia with Lewy Bodies" (2020) in Neurotherapeutics
  • "Effects of innate immune receptor stimulation on extracellular α-synuclein uptake and degradation by brain resident cells" (2021) in Experimental & Molecular Medicine
  • "Role of Alterations in Protein Kinase p38γ in the Pathogenesis of the Synaptic Pathology in Dementia With Lewy Bodies and α-Synuclein Transgenic Models" (2020) in Frontiers in Neuroscience
  • "Nicotine-mediated effects in neuronal and mouse models of synucleinopathy" (2023) in Frontiers in Neuroscience
  • "RETRACTED ARTICLE: Efficacy and immunogenicity of MultiTEP-based DNA vaccines targeting human α-synuclein: prelude for IND enabling studies" (2022) in npj Vaccines

The scientist frequently publishes in several venues, including:

  • Frontiers in Neuroscience
  • npj Vaccines
  • Neurobiology of Disease
  • Neuron
  • Molecular Therapy

Edward Rockenstein has collaborated extensively with multiple researchers, including:

  • Eliezer Masliah
  • Anthony Adame
  • Changyoun Kim
  • Michael Mante
  • Brian Spencer

Best Publications

  • Dopaminergic Loss and Inclusion Body Formation in α-Synuclein Mice: Implications for Neurodegenerative Disorders

    Eliezer Masliah;Edward Rockenstein;Isaac Veinbergs;Margaret Mallory

  • High-level neuronal expression of abeta 1-42 in wild-type human amyloid protein precursor transgenic mice: synaptotoxicity without plaque formation.

    Lennart Mucke;Eliezer Masliah;Gui-Qiu Yu;Margaret Mallory

  • Inclusion formation and neuronal cell death through neuron-to-neuron transmission of alpha-synuclein.

    Paula Desplats;He Jin Lee;Eun Jin Bae;Christina Patrick

  • Axonopathy and transport deficits early in the pathogenesis of Alzheimer's disease.

    Gorazd B. Stokin;Concepción Lillo;Tomás L. Falzone;Richard G. Brusch

  • The autophagy-related protein beclin 1 shows reduced expression in early Alzheimer disease and regulates amyloid β accumulation in mice

    Fiona Pickford;Eliezer Masliah;Markus Britschgi;Kurt Lucin

  • Neuroprotective effects of brain-derived neurotrophic factor in rodent and primate models of Alzheimer's disease

    Alan H Nagahara;David A Merrill;Giovanni Coppola;Shingo Tsukada

  • α-Synuclein Promotes Mitochondrial Deficit and Oxidative Stress

    Leigh J. Hsu;Yutaka Sagara;Armando Arroyo;Edward Rockenstein

  • β-Amyloid peptides enhance α-synuclein accumulation and neuronal deficits in a transgenic mouse model linking Alzheimer's disease and Parkinson's disease

    Eliezer Masliah;Edward Rockenstein;Isaac Veinbergs;Yutaka Sagara

  • Central nervous system damage produced by expression of the HIV-1 coat protein gp120 in transgenic mice.

    Stephanie M. Toggas;Eliezer Masliah;Edward M. Rockenstein;Glenn F. Rail

  • Beclin 1 Gene Transfer Activates Autophagy and Ameliorates the Neurodegenerative Pathology in α-Synuclein Models of Parkinson's and Lewy Body Diseases

    Brian Spencer;Rewati Potkar;Margarita Trejo;Edward Rockenstein

  • Role of protein aggregation in mitochondrial dysfunction and neurodegeneration in Alzheimer's and Parkinson's diseases.

    Makoto Hashimoto;Edward Rockenstein;Leslie Crews;Eliezer Masliah

  • Effects of α-Synuclein Immunization in a Mouse Model of Parkinson’s Disease

    Eliezer Masliah;Edward Rockenstein;Anthony Adame;Michael Alford

  • Nitrosative stress linked to sporadic Parkinson's disease: S-nitrosylation of parkin regulates its E3 ubiquitin ligase activity

    Dongdong Yao;Zezong Gu;Tomohiro Nakamura;Zhong Qing Shi

  • beta-Synuclein inhibits alpha-synuclein aggregation: a possible role as an anti-parkinsonian factor.

    Makoto Hashimoto;Edward Rockenstein;Michael Mante;Margaret Mallory

  • Differential neuropathological alterations in transgenic mice expressing α-synuclein from the platelet-derived growth factor and Thy-1 promoters

    Edward Rockenstein;Margaret Mallory;Makoto Hashimoto;David Song;David Song

  • Early and Progressive Sensorimotor Anomalies in Mice Overexpressing Wild-Type Human α-Synuclein

    Sheila M. Fleming;Jonathan Salcedo;Pierre-Olivier Fernagut;Edward Rockenstein

  • Targeting BACE1 with siRNAs ameliorates Alzheimer disease neuropathology in a transgenic model

    Oded Singer;Robert A Marr;Edward Rockenstein;Leslie Crews

  • Pericytes of Multiple Organs Do Not Behave as Mesenchymal Stem Cells In Vivo

    Nuno Guimarães-Camboa;Nuno Guimarães-Camboa;Paola Cattaneo;Yunfu Sun;Thomas Moore-Morris

  • Passive Immunization Reduces Behavioral and Neuropathological Deficits in an Alpha-Synuclein Transgenic Model of Lewy Body Disease

    Eliezer Masliah;Edward Rockenstein;Michael Mante;Leslie Crews

  • Neprilysin Gene Transfer Reduces Human Amyloid Pathology in Transgenic Mice

    Robert A. Marr;Edward Rockenstein;Atish Mukherjee;Mark S. Kindy

Frequent Co-Authors

Eliezer Masliah
Eliezer Masliah National Institutes of Health
Michael Mante
Michael Mante University of California, San Diego
Leslie Crews
Leslie Crews University of California, San Diego
Robert A. Rissman
Robert A. Rissman University of California, San Diego
Margaret Mallory
Margaret Mallory University of California, San Diego
Beate Winner
Beate Winner University of Erlangen-Nuremberg
Mark H. Tuszynski
Mark H. Tuszynski University of California, San Diego
Fred H. Gage
Fred H. Gage Salk Institute for Biological Studies
Lennart Mucke
Lennart Mucke University of California, San Francisco
Douglas Galasko
Douglas Galasko University of California, San Diego

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